Laminin-5γ2 chain expression in cervical intraepithelial neoplasia and invasive cervical carcinoma

Acta Obstetricia et Gynecologica Scandinavica

Volumn 84, Issue 11, 2005, Pages 1119-1123

  Noel, Jean Christophe ^a   Fernandez Aguilar, S ^a   Fayt, I ^a   Buxant, F ^a   Ansion, M H ^a   Simon, P ^a   Anaf, V ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

Carcinoma; Cervical intraepithelial neoplasia; Dysplasia; Human papillomavirus; Laminin; Laminin 5 2 chain, cervix; p16 protein

Indexed keywords

KALININ; LAMININ 5GAMMA2; PROTEIN P16; UNCLASSIFIED DRUG;

ARTICLE; CANCER GROWTH; CANCER INVASION; CARCINOGENESIS; CELL MIGRATION; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KERATINOCYTE; LYMPH NODE METASTASIS; PRIORITY JOURNAL; TUMOR GROWTH; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU;

CARCINOMA, SQUAMOUS CELL; CELL ADHESION MOLECULES; CERVICAL INTRAEPITHELIAL NEOPLASIA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P16; GENES, TUMOR SUPPRESSOR; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM INVASIVENESS; PAPILLOMAVIRIDAE; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 27644595336     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0001-6349.2005.00879.x     Document Type: Article

References (26)

1. Gad C. The management and natural history of severe dysplasia and carcinoma in situ of the uterine cervix. Br J Obstet Gynaecol 1976; 83: 554-59.
2. Kottmeier H. Evolution et traitement des epitheliomas. Rev Fr Gynecol Obstet 1961; 56: 821-26.
3. McIndoe W, McLean M, Jones R. The invasive potential of in situ carcinoma of the cervix. Obstet Gynecol 1984; 64: 451-58.
4. Spriggs A. Follow-up of untreated carcinoma in situ of the cervix uteri. Lancet 1971; 2: 599-600.
5. Beck K, Hunter I, Engel J. Structure and function of laminin: anatomy of a multidomain glycoprotein. FASEB J 1990; 4: 148-60.
6. Yurchenco P, Schittny J. Molecular architecture of basement membranes. FASEB J 1990; 4: 1577-90.
7. Colognato H, Yurchenco P. Form and function. The laminin family of heterotrimers. Dev Dyn 2000; 218: 213-34.
8. Engvall E, Wewer U. Domains of laminin. J Cell Biochem 1996; 61: 493-501.
9. Burgeson R, Chiquet M, Deutzmann R, Ekblom P, Engel J, Kleinman H et al. A new nomenclature for the laminins. Matrix Biol 1994; 14: 209-11.
10. Carter W, Ryan M, Gahr P. Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes. Cell 1991; 65: 599-610.
11. Rousselle P, Lunstrum G, Keene D, Burgeson R. Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J Cell Biol 1991; 114: 567-76.
12. INK4A and laminin 5γ2 by microinvasive and superficial squamous cell carcinomas in vivo and migrating wound and senescent keratinocytes in culture. Am J Pathol 2003; 163: 477-91.
13. Masaki T, Sugiyama M, Matsuoka H, Abe N, Izumisato Y, Sakamoto I et al. Coexpression of matrilysin and laminin-5 gamma 2 chain may contribute to tumor cell migration in colorectal carcinomas. Dig Dis Sci 2003; 48: 1262-67.
14. Lohi J. Laminin-5 in the progression of carcinomas. Int J Cancer 2001; 94: 763-67.
15. Pyke C, Romer J, Kallunki P, Lund L, Ralfkiaer E, Dano K et al. The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers. Am J Pathol 1994; 145: 782-91.
16. Lundgren C, Frankendal B, Silfversward C, Nilsson B, Tryggvason K, Auer G et al. Laminin-5 gamma 2 chain expression and DNA ploidy as predictors of prognosis in endometrial carcinoma. Med Oncol 2003; 20: 147-56.
17. Nordström B, Einhorn N, Silfverswärd C, Sjövall K, Tryggvason K, Auer G. Laminin-572 chain as an invasivity marker for uni and multifocal lesions in the lower anogenital tract. Int J Gynecol Cancer 2002; 12: 105-9.
18. Pyke C, Salo S, Ralfkiaer E, Romer J, Dano K, Tryggvason K. Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 1995; 55: 4132-9.
19. Lenander C, Habermann J, Ost A, Nilsson B, Schimmelpenning H, Tryggvason K et al. Laminin-5 gamma 2 chain expression correlates with unfavourable prognosis in colon carcinomas. Anal Cell Pathol 2001; 22: 201-9.
20. Stoltzfus P, Salo S, Eriksson E, Aspenblad U, Tryggvason K, Auer G et al. Laminin-5γ2 chain expression facilitates detection of invasive squamous cell carcinoma of the uterine cervix. Int J Gynecol Pathol 2004; 23: 215-22.
21. INKA as a specific marker fordysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer 2001; 92: 276-84.
22. Salomon D, Schiffman M, Tarone R. Comparison of three management strategies for patient with atypical squamous cells of undetermined significance: baseline results from a randomized trial. J Natl Cancer Inst 2001; 93: 293-99.
23. Skyldberg B, Salo S, Eriksson E, Aspenblad U, Moberger B, Tryggvason K et al. Laminin-5 as a marker of invasiveness in cervical lesions. J Natl Cancer Inst 1999; 91: 1882-87.
24. Kohlberger P, Beneder C, Horvat R, Leodolter S, Breitenecker G. Immunohistochemical expression of laminin-5 in cervical intraepithelial neoplasia. Gynecol Oncol 2003; 89: 391-94.
25. Morgan P, Anderson M, Buckley C, Murdoch J, Lopes A, Duncan I et al. The royal college of obstetricians and gynaecologist microinvasive carcinoma of the cervix study: preliminary results. Br J Obstet Gynaecol 1993; 100: 664-68.
26. Sedlis A, Sall S, Tsukada Y, Park R, Mangan C, Shingleton H et al. Microinvasive carcinoma of the uterine cervix: a clinical-pathologic study. Am J Obstet Gynecol 1979; 1: 64-74.