The SDF-1/CXCR4 pathway and the development of the cerebellar system

European Journal of Neuroscience

Volumn 22, Issue 8, 2005, Pages 1831-1839

  Vilz, Tim O ^a   Moepps, Barbara ^b   Engele, Jürgen ^c   Molly, Sabine ^a   Littman, Dan R ^d   Schilling, Karl ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebellum; Inhibitory interneurons; Mouse; Neuronal migration; Pontine nuclei; Precerebellar system

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CEREBELLUM CORTEX; CONTROLLED STUDY; GRANULE CELL; INTERNEURON; MITOSIS; MOUSE; MOUSE STRAIN; NERVE CELL DIFFERENTIATION; NONHUMAN; PONS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRAIN DIFFERENCE; SYNAPSE; WILD TYPE;

ANIMALS; BRAIN STEM; BROMODEOXYURIDINE; CELL MOVEMENT; CELLS, CULTURED; CEREBELLUM; CHEMOKINES, CXC; EMBRYO; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, KNOCKOUT; NEURONS; PAX2 TRANSCRIPTION FACTOR; PHOSPHOPYRUVATE HYDRATASE; PREGNANCY; RECEPTORS, CXCR4;

EID: 27644582810     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04378.x     Document Type: Article

References (39)

1. Altman, J. & Bayer, S.A. (1997) Development of the Cerebellar System in Relation to its Evolution, Structure, and Functions. CRC Press, Boca Raton.
2. Arakawa, Y., Bito, H., Furuyashiki, T., Tsuji, T., Takemoto-Kimura, S., Kimura, K., Nozaki, K., Hashimoto, N. & Narumiya, S. (2003) Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons. J. Cell Biol., 161, 381-391.
3. Bagri, A., Gurney, T., He, X., Zou, Y.R., Littman, D.R., Tessier-Lavigne, M. & Pleasure, S.J. (2002) The chemokine SDF1 regulates migration of dentate granule cells. Development, 129, 4249-4260.
4. Cardones, A.R., Murakami, T. & Hwang, S.T. (2003) CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta (1) integrin. Cancer Res., 63, 6751-6757.
5. Causeret, F., Hidalgo-Sanchez, M., Fort, P., Backer, S., Popoff, M.R., Gauthier-Rouviere, C. & Bloch-Gallego, E. (2004) Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1. Development, 131, 2841-2852.
6. Chalasani, S.H., Sabelko, K.A., Sunshine, M.J., Littman, D.R. & Raper, J.A. (2003) A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is required for normal axon pathfinding. J. Neurosci., 23, 1360-1371.
7. Diaz, E., Ge, Y., Yang, Y.H., Loh, K.C., Serafini, T.A., Okazaki, Y., Hayashizaki, Y., Speed, T.P., Ngai, J. & Scheiffele, P. (2002) Molecular analysis of gene expression in the developing pontocerebellar projection system. Neuron, 36, 417-434.
8. Engelkamp, D., Rashbass, P., Seawright, A. & van Heyningen, V. (1999) Role of Pax6 in development of the cerebellar system. Development, 126, 3585-3596.
9. Gesemann, M., Litwack, E.D., Yee, K.T., Christen, U. & O'Leary, D.D. (2001) Identification of candidate genes for controlling development of the basilar pons by differential display PCR. Mol. Cell Neurosci., 18, 1-12.
10. Gitler, A.D., Lu, M.M. & Epstein, J.A. (2004) PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Dev. Cell. 1, 107-116.
11. Hartmann, W., Koch, A., Brune, H., Waha, A., Schuller, U., Dani, I., Denkhaus, D., Langmann, W., Bode, U., Wiestler, O.D., Schilling, K. & Pietsch, T. (2005) Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. Am. J. Pathol., 166, 1153-1162.
12. Hatten, M.E. (1999) Central nervous system neuronal migration. Annu. Rev. Neurosci., 22, 511-539.
13. Hausmann, B. & Sievers, J. (1985) Cerebellar external granule cells are attached to the basal lamina from the onset of migration up to the end of their proliferative activity. J. Comp. Neurol., 241, 50-62.
14. Horie, M., Sango, K., Takeuchi, K., Honma, S., Osumi, N., Kawamura, K. & Kawano, H. (2003) Subpial neuronal migration in the medulla oblongata of Pax-6-deficient rats. Eur. J. Neurosci., 17, 49-57.
15. Kyriakopoulou, K., de Diego, I., Wassef M. & Karagogeos, D. (2002) A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla. Development, 129, 287-296.
16. Lu, Q., Sun, E.E., Klein, R.S. & Flanagan, J.G. (2001) Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell, 105, 69-79.
17. Ma, Q., Jones, D., Borghesani, P.R., Segal, R.A., Nagasawa, T., Kishimoto, T., Bronson, R.T. & Springer, T.A. (1998) Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl Acad. Sci. USA, 95, 9448-9453.
18. Ma, X., Kawamoto, S., Hara, Y. & Adelstein, R.S. (2004) A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol. Biol. Cell, 15, 2568-2579.
19. Maricich, S.M. & Herrup, K. (1999) Pax-2 expression defines a subset of GABAergic interneurons and their precursors in the developing murine cerebellum. J. Neurobiol., 41, 281-294.
20. i2 are differentially expressed in vivo. Eur. J. Immunol., 27, 2102-2112.
21. Napieralski, J.A. & Eisenman, L.M. (1993) Developmental analysis of the external granule cell layer in the meander tail mutant mouse: do cerebellar microneurons have independent progenitors? Dev. Dyn., 197, 244-254.
22. Oberdick, J., Baader, S.L. & Schilling, K. (1998) From zebra stripes to postal zones: deciphering patterns of gene expression in the cerebellum. Trends Neurosci., 21, 383-391.
23. Orkand, P.M., Lindner, J. & Schachner, M. (1984) Specificity of histiotypic organization and synaptogenesis in reaggregating cell cultures of mouse cerebellum. Brain Res., 318, 119-134.
24. Peled, A., Grabovsky, V., Habler, L., Sandbank, J., Arenzana-Seisdedos, F., Petit, I., Ben Hur, H., Lapidot, T. & Alon, R. (1999) The chemokine SDF-1 stimulates integrin-mediated arrest of CD34 (+) cells on vascular endothelium under shear flow. J. Clin. Invest., 104, 1199-1211.
25. Rey, M., Vicente-Manzanares, M., Viedma, F., Yanez-Mo, M., Urzainqui, A., Barreiro, O., Vazquez, J. & Sanchez-Madrid, F. (2002) Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes. J. Immunol., 169, 5410-5414.
26. Rodriguez, C.I. & Dymecki, S.M. (2000) Origin of the precerebellar system. Neuron, 27, 475-486.
27. Schwarz, C. & Thier, P. (1995) Modular organization of the pontine nuclei: dendritic fields of identified pontine projection neurons in the rat respect the borders of cortical afferent fields. J. Neurosci., 15, 3475-3489.
28. Solowska, J.M., Mazurek, A., Weinberger, L. & Baird, D.H. (2002) Pontocerebellar axon guidance: neuropilin-1- and semaphorin 3A-sensitivity gradients across basilar pontine nuclei and semaphorin 3A variation across cerebellum. Mol. Cell Neurosci., 21, 266-284.
29. Sotelo, C. (2004) Cellular and genetic regulation of the development of the cerebellar system. Prog. Neurobiol., 72, 295-339.
30. Stumm, R.K., Zhou, C., Ara, T., Lazarini, F., Dubois-Dalcq, M., Nagasawa, T., Hollt, V. & Schulz, S. (2003) CXCR4 regulates interneuron migration in the developing neocortex. J. Neurosci., 23, 5123-5130.
31. Taber Pierce, E. (1966) Histogenesis of the nuclei griseum pontis, corporis pontobulbaris and reticularis tegmenti pontis (Bechterew) in the mouse. J. Comp. Neurol., 126, 219-240.
32. Tissir, F., Wang, C.E. & Goffinet, A.M. (2004) Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development. Brain Res. Dev. Brain Res., 149, 63-71.
33. Ventura, L., Bologna, M., Ventura, T., Colimberti, P. & Leocata, P. (2001) Agar specimen orientation technique revisited: a simple and effective method in histopathology. Ann. Diagn. Pathol., 5, 107-109.
34. Vicente-Manzanares, M., Cabrero, J.R., Rey, M., Perez-Martinez, M., Ursa, A., Itoh, K. & Sanchez-Madrid, F. (2002) A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1 alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis. J. Immunol., 168, 400-410.
35. Weisheit, G., Mertz, D., Schilling, K. & Viebahn, C. (2002) An efficient in situ hybridization protocol for multiple tissue sections and probes on miniaturized slides. Dev. Genes Evol., 212, 403-406.
36. Weyer, A. & Schilling, K. (2003) Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum. J. Neurosci. Res., 73, 400-409.
37. Wylie, S.R. & Chantler, P.D. (2003) Myosin IIA drives neurite retraction. Mol. Biol. Cell, 14, 4654-4666.
38. Zhang, L. & Goldman, J.E. (1996) Generation of cerebellar interneurons from dividing progenitors in white matter. Neuron, 16, 47-54.
39. Zuo, Y.-R., Kottmann, A.H., Kuroda, M., Taniuchi, I. & Littman, D.R. (1998) Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature, 393, 595-599.