Rare Congolese Plasmodium falciparum DHFR alleles

Molecular and Biochemical Parasitology

Volumn 144, Issue 2, 2005, Pages 227-229

  Wilson, Paul E ^a   Kazadi, Walter ^b   Alker, Alisa P ^c   Meshnick, Steven R ^c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b Programme National de Lutte Contre le Paludisme (PNLP)   (Congo)

^c IL   (United States)

Author keywords

Democratic Republic of the Congo; DNA; Drug resistance; Genotype; Microbial; Plasmodium falciparum; Polymerase chain reaction; Sequence analysis; Single nucleotide polymorphism; Sulfadoxine pyrimethamine

Indexed keywords

DIHYDROFOLATE REDUCTASE;

ALLELE; ARTICLE; CASE REPORT; CHILD; CONGO; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; HUMAN; INFANT; MALARIA FALCIPARUM; NUCLEOTIDE SEQUENCE; PARASITEMIA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANIMALS; ANTIMALARIALS; CHILD, PRESCHOOL; CONGO; DRUG COMBINATIONS; DRUG RESISTANCE; GENES, PROTOZOAN; HUMANS; INFANT; MALARIA, FALCIPARUM; MUTATION; PLASMODIUM FALCIPARUM; PYRIMETHAMINE; SULFADOXINE; TETRAHYDROFOLATE DEHYDROGENASE;

PLASMODIUM FALCIPARUM;

EID: 27644582620     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2005.08.008     Document Type: Article

References (14)

1. K.N. Suh, K.C. Kain, and J.S. Keystone Malaria CMAJ 170 11 2004 1693 1702
2. F. Mendez, A. Munoz, and G. Carrasquilla Determinants of treatment response to sulfadoxine-pyrimethamine and subsequent transmission potential in falciparum malaria Am J Epidemiol 156 3 2002 230 238
3. J.G. Kublin, R.S. Witzig, and A.H. Shankar Molecular assays for surveillance of antifolate-resistant malaria Lancet 351 9116 1998 1629 1630
4. T. Smith, I. Felger, M. Tanner, and H.P. Beck Premunition in Plasmodium falciparum infection: insights from the epidemiology of multiple infections Trans R Soc Trop Med Hyg 93 Suppl. 1 1999 59 64
5. C.V. Plowe, J.F. Cortese, and A. Djimde Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance J Infect Dis 176 6 1997 1590 1596
6. A.P. Alker, V. Mwapasa, and S.R. Meshnick Rapid real-time PCR genotyping of mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum Antimicrob Agents Chemother 48 8 2004 2924 2929
7. S. Rozen, and H. Skaletsky Primer3 on the WWW for general users and for biologist programmers S. Misener Bioinformatics methods and protocols: methods in molecular biology 2000 Humana Press Totowa, NJ 365 386
8. J.D. Thompson, T.J. Gibson, F. Plewniak, F. Jeanmougin, and D.G. Higgins The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools Nucleic Acids Res 25 24 1997 4876 4882
9. K.Y. Chung, N.G. Kim, L.S. Li, H. Kim, C.M. Nam, and D.H. Shin Clinicopathologic characteristics related to the high variability of coding mononucleotide repeat sequences in tumors with high-microsatellite instability Oncol Rep 10 2 2003 439 444
10. H. Orimo, E. Nakajima, M. Ikejima, M. Emi, and T. Shimada Frameshift mutations and a length polymorphism in the hMSH3 gene and the spectrum of microsatellite instability in sporadic colon cancer Jpn J Cancer Res 90 12 1999 1310 1315
11. Z. Piao, W. Fang, and S. Malkhosyan Frequent frameshift mutations of RIZ in sporadic gastrointestinal and endometrial carcinomas with microsatellite instability Cancer Res 60 17 2000 4701 4704
12. A. Paoloni-Giacobino, C. Rey-Berthod, A. Couturier, S.E. Antonarakis, and P. Hutter Differential rates of frameshift alterations in four repeat sequences of hereditary nonpolyposis colorectal cancer tumors Hum Genet 111 3 2002 284 289
13. J.F. Cortese, and C.V. Plowe Antifolate resistance due to new and known Plasmodium falciparum dihydrofolate reductase mutations expressed in yeast Mol Biochem Parasitol 94 2 1998 205 214
14. P. Wang, R.K. Brobey, T. Horii, P.F. Sims, and J.E. Hyde Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy Mol Microbiol 32 6 1999 1254 1262