메뉴 건너뛰기




Volumn 65, Issue 2, 2005, Pages 50-54

Growth hormone secretagogue receptor antagonists as potential therapeutic agents for obesity

Author keywords

Antagonist; Ghrelin; Growth hormone secretagogue receptor

Indexed keywords

AMIDE; ANTISENSE OLIGONUCLEOTIDE; APPETITE STIMULANT; GHRELIN; GROWTH HORMONE SECRETAGOGUE RECEPTOR; GROWTH HORMONE SECRETAGOGUE RECEPTOR ANTAGONIST; ISOXAZOLE DERIVATIVE; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

EID: 27644576034     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.20011     Document Type: Review
Times cited : (8)

References (26)
  • 1
  • 2
    • 0036157858 scopus 로고    scopus 로고
    • Ghrelin and leptin pulse discharge in fed and fasted rats
    • Bagnasco M, Kalra PS, Kalra SP. 2002. Ghrelin and leptin pulse discharge in fed and fasted rats. Endocrinology 143:726-729.
    • (2002) Endocrinology , vol.143 , pp. 726-729
    • Bagnasco, M.1    Kalra, P.S.2    Kalra, S.P.3
  • 3
    • 0037471384 scopus 로고    scopus 로고
    • Endogenous ghrelin is an orexigenic peptide acting in the arcuate nucleus in response to fasting
    • Bagnasco M, Tulipano G, Melis MR, Argiolas A, Cocchi D, Muller EE. 2003. Endogenous ghrelin is an orexigenic peptide acting in the arcuate nucleus in response to fasting. Regul Pept 111: 161-167.
    • (2003) Regul Pept , vol.111 , pp. 161-167
    • Bagnasco, M.1    Tulipano, G.2    Melis, M.R.3    Argiolas, A.4    Cocchi, D.5    Muller, E.E.6
  • 5
    • 0036848562 scopus 로고    scopus 로고
    • Recent developments in ghrelin receptor (GHS-R1a) agonists and antagonists
    • Carpino PA. 2002. Recent developments in ghrelin receptor (GHS-R1a) agonists and antagonists. Expert Opin Ther Patents 12: 1599-1618.
    • (2002) Expert Opin Ther Patents , vol.12 , pp. 1599-1618
    • Carpino, P.A.1
  • 9
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. 1999. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 10
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombarde F, Dominy BW, Feeney PJ. 1997. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Delivery Rev 23:3-25.
    • (1997) Adv Drug Delivery Rev , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombarde, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 16
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun Y, Ahmed S, Smith RG. 2003. Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 23:7973-7981.
    • (2003) Mol Cell Biol , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 17
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun Y, Wang P, Zheng H, Smith RG. 2004. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci USA 101:4679-4684.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 19
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M, Smiley DL, Heiman ML. 2000. Ghrelin induces adiposity in rodents. Nature 407:908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 25
    • 11144244631 scopus 로고    scopus 로고
    • Discovery of tetralin carboxamide growth hormone secretagogue receptor antagonists via scaffold manipulation
    • Zhao H, Xin Z, Liu G, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL. 2004. Discovery of tetralin carboxamide growth hormone secretagogue receptor antagonists via scaffold manipulation. J Med Chem 47:6655-6657.
    • (2004) J Med Chem , vol.47 , pp. 6655-6657
    • Zhao, H.1    Xin, Z.2    Liu, G.3    Schaefer, V.G.4    Falls, H.D.5    Kaszubska, W.6    Collins, C.A.7    Sham, H.L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.