Bursting electrical activity generated in the presence of KATP channel blockers: Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism

Advances in Experimental Medicine and Biology

Volumn 426, Issue , 1997, Pages 33-41

  Santos, Rosa M ^a,b   Barbosa, Rui M ^a,c   Antunes, Célia M ^a   Silva, Amelia M ^a   Salgado, António P ^a   Abrunhosa, Antero J ^a   Pereira, Frederico C ^a   Seiça, Raquel M ^a,d   Rosário, Luis M ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 27644571070     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-1819-2_5     Document Type: Article

References (20)

1. Ashcroft, F.M., and Rorsman, P. , 1989, Electrophysiology of the pancreatic β-cell, Prog. Biophys. mol. biol. 54: 87-143
2. Atwater, I., Carroll, P., and Li, M.X., 1989, Electrophysiology of the pancreatic β-cell, in: "Insulin secretion". Alan R. Liss, Inc., pp. 49-68
3. 2+ levels trigger membrane potential oscillations in mouse pancreatic β-cells during blockade of K(ATP) channels, Biochem. Biophys. Res. Commun. 187: 872-879
4. 2+ channels, Pflugers Arch. 424: 439-447
5. Barbosa, R.M., Salgado, A.P., Santos, R.M., and Rosário, L.M., 1993, Differential modulation of pancreatic β-cell bursting by intracellular pH in the presence and absence of a K-ATP channel blocker, FEBS Lett. 332: 9-13
6. 2+]-sensitive conductance in the regulation of pancreatic B-cell bursting, in: "Insulin secretion and pancreatic B-cell research", P.R. Flatt and S. Lenzen, eds., Smith-Gordon, USA, pp. 181-186
7. 2+, diphenylamine-2-carboxylate, and glucose metabolism, J. Biol. Chem. 269: 17095-17103
8. Harkness, J.E., and Wagner, J.E., 1989, "The Biology and Medicine of Rabbits and Rodents", Lea & Febiger, Philadelphia and London
9. Atwater, I., Frankel, B.J., Rojas, E., and Grodsky, G.M., 1983, β-cell membrane potential and insulin release: role of calcium and calcium:magnesium ratio, Quart. J. Exp. Physiol. 68: 233-245
10. 2+ concentration resembling bursting electrical activity in single mouse islets of Langerhans, FEBS Lett. 259: 19-23
11. 2+], oscillations due to bursting electrical activity in single pancreatic islets, Pflugers Arch. 418: 417-422
12. Rosario, L.M., Atwater, I., and Scott, A.M., 1986, Pulsatile insulin release and electrical activity from single ob/ob mouse islets of Langcrhans, in: "Biophysics of the pancreatic B-cell", 1. Atwater, E. Rojas and B. Soria, eds., Plenum Publishing Corporation, pp. 203-215
13. + channel by intracellular pH in B cells of the pancreatic islet, J. Membrane Biol. 109: 135-143
14. + conductance by intracellular pH in pancreatic β-cells, FEBS Lett. 200: 203-209
15. Partridge, L.D., and Swandulla, D., 1988, Calcium-activated non-specific cation channels, TINS 11: 69-720
16. Sturgess, N.C., Hales, C.N., and Ashford, M.L.J., 1987, Calcium and ATP regulate the activity of a non-selective cation channel in a rat insulinoma cell line. Pflugers Arch. 409: 607-615
17. Sturgess, N.C., Carrington, C.A., Hales, C.N., and Ashford, M.L.J., 1987, Nucleotide-sensitive ion channels in human insulin producing tumour cells. Pflugers Arch. 410: 169-172
18. Gogelein, H., and Pfannmuller, B., 1989, The nonselective cation channel in the basolateral membrane of rat exocrine pancreas, Pflugers Arch. 413: 287-298
19. Cook, D.I., Poronnik, P., and Young, J.A., 1990, Characterization of a 25-pS nonselective cation channel in a cultured secretory epithelial cell line, J. Membrane Biol. 114: 37-52
20. --transporting epithelia, Pflugers Arch. 405 (Suppl.1):S95-S100