A random sampling approach for robust estimation of tissue-to-plasma ration from extremely sparse data

AAPS Journal

Volumn 7, Issue 1, 2005, Pages

  Chu, Hui May ^a   Ette, Ene I ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

Convergence; Paired extremely sparsely sample data; Pseudo profile based approach; Random sampling approach; Robustness; Tissue to plasma ratio

Indexed keywords

ALGORITHM; AREA UNDER THE CURVE; ARTICLE; CALCULATION; DATA BASE; NONHUMAN; NONPARAMETRIC TEST; RANDOMIZATION; SAMPLING; STATISTICAL ANALYSIS;

ALGORITHMS; ANIMALS; AREA UNDER CURVE; PHARMACOKINETICS; PLASMA; RANDOM ALLOCATION; RATS; SAMPLING STUDIES; STATISTICS, NONPARAMETRIC; TOXICOLOGY;

EID: 27644561297     PISSN: 15221059     EISSN: 15221059     Source Type: Journal    
DOI: 10.1208/aapsj070124     Document Type: Article

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