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Volumn 3, Issue , 2005, Pages

Heparin-induced thrombocytopenia: An update

Author keywords

Heparin; Platelets; Thrombosis

Indexed keywords

ARGATROBAN; DANAPAROID; DEXTRAN 70; HEPARIN; IMMUNOGLOBULIN G ANTIBODY; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; THROMBOCYTE FACTOR 4;

EID: 27644553521     PISSN: 14779560     EISSN: 14779560     Source Type: Journal    
DOI: 10.1186/1477-9560-3-14     Document Type: Review
Times cited : (114)

References (53)
  • 1
    • 0141609865 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia
    • Chong BH: Heparin-induced thrombocytopenia. J Thromb Haemost 2003, 1:1471-1478.
    • (2003) J. Thromb. Haemost. , vol.1 , pp. 1471-1478
    • Chong, B.H.1
  • 2
    • 19644398319 scopus 로고    scopus 로고
    • When heparins promote thrombosis. Review of heparin-induced thrombocytopenia
    • Jang I-K, Hursting HJ: When heparins promote thrombosis. Review of heparin-induced thrombocytopenia. Circulation 2005, 111:2671-2683.
    • (2005) Circulation , vol.111 , pp. 2671-2683
    • Jang, I.-K.1    Hursting, H.J.2
  • 3
    • 0038392539 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Pathogenesis and management
    • Warkentin TE: Heparin-induced thrombocytopenia: pathogenesis and management. Br J Haematol 2003, 121:535-555.
    • (2003) Br. J. Haematol. , vol.121 , pp. 535-555
    • Warkentin, T.E.1
  • 4
    • 21344446637 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia. Diagnosis and management
    • Warkentin TE: Heparin-induced thrombocytopenia. Diagnosis and management. Circulation 2004, 110:e454-458.
    • (2004) Circulation , vol.110
    • Warkentin, T.E.1
  • 6
    • 4644242157 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Recognition, treatment, and prevention: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Warkentin TE, Greinacher A: Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004, 126(3 Suppl):311S-337S.
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Warkentin, T.E.1    Greinacher, A.2
  • 7
    • 0036348390 scopus 로고    scopus 로고
    • Thrombocytopenia in patients in the medical intensive care unit: Bleeding prevalence, transfusion requirements, and outcome
    • Strauss R, Wehler M, Mehler K, Kreutzer D, Koebnick C, Hahn EG: Thrombocytopenia in patients in the medical intensive care unit: bleeding prevalence, transfusion requirements, and outcome. Crit Care Med 2002, 30:1765-1771.
    • (2002) Crit. Care Med. , vol.30 , pp. 1765-1771
    • Strauss, R.1    Wehler, M.2    Mehler, K.3    Kreutzer, D.4    Koebnick, C.5    Hahn, E.G.6
  • 8
    • 3843135119 scopus 로고    scopus 로고
    • An overview of the heparin-induced thrombocytopenia syndrome
    • Warkentin TE: An overview of the heparin-induced thrombocytopenia syndrome. Semin Thromb Hemost 2004, 30:273-283.
    • (2004) Semin. Thromb. Hemost. , vol.30 , pp. 273-283
    • Warkentin, T.E.1
  • 9
    • 6344281156 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Myths and misconceptions (that will cause trouble for you and your patient)
    • Rice L: Heparin-induced thrombocytopenia: myths and misconceptions (that will cause trouble for you and your patient). Arch Intern Med 2004, 164:1961-1964.
    • (2004) Arch. Intern. Med. , vol.164 , pp. 1961-1964
    • Rice, L.1
  • 10
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, et al: Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995, 332:1330-1335.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3
  • 11
    • 0036213008 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: An overview
    • Kelton JG: Heparin-induced thrombocytopenia: an overview. Blood Rev 2002, 16:77-80.
    • (2002) Blood Rev. , vol.16 , pp. 77-80
    • Kelton, J.G.1
  • 12
    • 0030934251 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia/thrombosis syndrome (HIT): Diagnosis and treatment
    • Baglin TP: Heparin-induced thrombocytopenia/thrombosis syndrome (HIT): diagnosis and treatment. Platelets 1997, 8:72-82.
    • (1997) Platelets , vol.8 , pp. 72-82
    • Baglin, T.P.1
  • 14
    • 0030983928 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia with thrombosis: Incidence, analysis of risk factors, and clinical outcomes in 108 consecutive patients treated at a single institution
    • Nand S, Wong W, Yuen B, Yetter A, Schmulbach E, Gross Fisher S: Heparin-induced thrombocytopenia with thrombosis: incidence, analysis of risk factors, and clinical outcomes in 108 consecutive patients treated at a single institution. Am J Hematol 1997, 56:12-16.
    • (1997) Am. J. Hematol. , vol.56 , pp. 12-16
    • Nand, S.1    Wong, W.2    Yuen, B.3    Yetter, A.4    Schmulbach, E.5    Gross Fisher, S.6
  • 15
    • 0038243178 scopus 로고    scopus 로고
    • The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin: A prospective cohort study
    • Girolami B, Prandoni P, Stefani PM, et al: The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin: a prospective cohort study. Blood 2003, 101:2955-2959.
    • (2003) Blood , vol.101 , pp. 2955-2959
    • Girolami, B.1    Prandoni, P.2    Stefani, P.M.3
  • 16
    • 0034004340 scopus 로고    scopus 로고
    • A prospective study on the incidence and clinical relevance of heparin-induced antibodies in patients after vascular surgery
    • Lindhoff-Last E, Eichler P, Stein M, et al: A prospective study on the incidence and clinical relevance of heparin-induced antibodies in patients after vascular surgery. Thromb Res 2000, 97:387-393.
    • (2000) Thromb. Res. , vol.97 , pp. 387-393
    • Lindhoff-Last, E.1    Eichler, P.2    Stein, M.3
  • 17
    • 27444445015 scopus 로고    scopus 로고
    • Rates of clinically apparent heparin-induced thrombocytopenia for unfractionated heparin vs. low molecular weight heparin in nonsurgical patients are low and similar
    • Locke CFS, Dooley J, Gerber J: Rates of clinically apparent heparin-induced thrombocytopenia for unfractionated heparin vs. low molecular weight heparin in nonsurgical patients are low and similar. Thrombosis J 2005, 3:4.
    • (2005) Thrombosis J. , vol.3 , pp. 4
    • Locke, C.F.S.1    Dooley, J.2    Gerber, J.3
  • 18
    • 0038657918 scopus 로고    scopus 로고
    • The pathophysiology of immune-mediated heparin-induced thrombocytopenia
    • Reilly RF: The pathophysiology of immune-mediated heparin-induced thrombocytopenia. Semin Dial 2003, 16:54-60.
    • (2003) Semin. Dial. , vol.16 , pp. 54-60
    • Reilly, R.F.1
  • 19
    • 1442265917 scopus 로고    scopus 로고
    • Pathogenesis of heparin-induced thrombocytopenia and thrombosis
    • Arepally G, Cines DB: Pathogenesis of heparin-induced thrombocytopenia and thrombosis. Autoimmun Rev 2002, 1:125-132.
    • (2002) Autoimmun. Rev. , vol.1 , pp. 125-132
    • Arepally, G.1    Cines, D.B.2
  • 20
    • 0028243705 scopus 로고
    • Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4
    • Kelton JG, Smith JW, Warkentin TE, Hayward CP, Denomme GA, Horsewood P: Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood 1994, 83:3232-3239.
    • (1994) Blood , vol.83 , pp. 3232-3239
    • Kelton, J.G.1    Smith, J.W.2    Warkentin, T.E.3    Hayward, C.P.4    Denomme, G.A.5    Horsewood, P.6
  • 21
    • 0023109003 scopus 로고
    • Immune endothelial-cell injury in heparin-associated thrombocytopenia
    • Cines DB, Tomaski A, Tannenbaum S: Immune endothelial-cell injury in heparin-associated thrombocytopenia. N Engl J Med 1987, 316:581-589.
    • (1987) N. Engl. J. Med. , vol.316 , pp. 581-589
    • Cines, D.B.1    Tomaski, A.2    Tannenbaum, S.3
  • 22
    • 0028009642 scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells
    • Visentin GP, Ford SE, Scott JP, Aster RH: Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J Clin Invest 1994, 93: 81-88.
    • (1994) J. Clin. Invest. , vol.93 , pp. 81-88
    • Visentin, G.P.1    Ford, S.E.2    Scott, J.P.3    Aster, R.H.4
  • 23
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocytopenia
    • Warkentin TE, Kelton JG: Temporal aspects of heparin-induced thrombocytopenia. N Engl J Med 2001, 334:1286-1292.
    • (2001) N. Engl. J. Med. , vol.334 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 24
    • 0035797925 scopus 로고    scopus 로고
    • Delayed-onset heparin-induced thrombocytopenia and thrombosis
    • Warkentin TE, Kelton JG. Delayed-onset heparin-induced thrombocytopenia and thrombosis. Ann Intern Med 2001, 135:502-506.
    • (2001) Ann. Intern. Med. , vol.135 , pp. 502-506
    • Warkentin, T.E.1    Kelton, J.G.2
  • 25
    • 0023919706 scopus 로고
    • Heparin-associated thrombocytopenia and thrombosis
    • Bell WR: Heparin-associated thrombocytopenia and thrombosis. J Lab Clin Med 1988, 111:600-605.
    • (1988) J. Lab. Clin. Med. , vol.111 , pp. 600-605
    • Bell, W.R.1
  • 26
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocytopenia
    • Warkentin TE, Kelton JG: A 14-year study of heparin-induced thrombocytopenia. Am J Med 1996, 101:502-507.
    • (1996) Am. J. Med. , vol.101 , pp. 502-507
    • Warkentin, T.E.1    Kelton, J.G.2
  • 27
    • 0028914288 scopus 로고
    • Antigen generation in heparin-associated thrombocytopenia: The nonimmunologic type and the immunologic type are closely linked in their pathogenesis
    • Greinacher A: Antigen generation in heparin-associated thrombocytopenia: the nonimmunologic type and the immunologic type are closely linked in their pathogenesis. Semin Thromb Hemost 1995, 21:106-116.
    • (1995) Semin. Thromb. Hemost. , vol.21 , pp. 106-116
    • Greinacher, A.1
  • 28
    • 0032742808 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: A clinicopathologic syndrome
    • Warkentin TE: Heparin-induced thrombocytopenia: a clinicopathologic syndrome. Thromb Haemost 1999, 82:439-447.
    • (1999) Thromb. Haemost. , vol.82 , pp. 439-447
    • Warkentin, T.E.1
  • 31
    • 0030054018 scopus 로고    scopus 로고
    • Heparin-induced skin lesions
    • Warkentin TE: Heparin-induced skin lesions. Br J Haematol 1996, 92:494-497.
    • (1996) Br. J. Haematol. , vol.92 , pp. 494-497
    • Warkentin, T.E.1
  • 32
    • 0016365620 scopus 로고
    • Disseminated intravascular coagulation during heparin therapy
    • Klein HG, Bell WR: Disseminated intravascular coagulation during heparin therapy. Ann Intern Med 1974, 80:477-481.
    • (1974) Ann. Intern. Med. , vol.80 , pp. 477-481
    • Klein, H.G.1    Bell, W.R.2
  • 33
    • 0037220153 scopus 로고    scopus 로고
    • How I treat heparin-induced thrombocytopenia and thrombosis
    • Alving BM: How I treat heparin-induced thrombocytopenia and thrombosis. Blood 2003, 101:31-37.
    • (2003) Blood , vol.101 , pp. 31-37
    • Alving, B.M.1
  • 34
  • 35
    • 0028826475 scopus 로고
    • Diagnosis, treatment and pathophysiology of immune-mediated thrombocytopenia
    • Chong BH: Diagnosis, treatment and pathophysiology of immune-mediated thrombocytopenia. Crit Rev Oncol Hematol 1995, 20:271-296.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.20 , pp. 271-296
    • Chong, B.H.1
  • 36
    • 0027442550 scopus 로고
    • Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with orgaran (Org 10172)
    • Magnani HN: Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172). Thromb Haemost 1993; 70:554-561.
    • (1993) Thromb. Haemost. , vol.70 , pp. 554-561
    • Magnani, H.N.1
  • 37
    • 0033543081 scopus 로고    scopus 로고
    • Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia
    • Heparin-Associated Thrombocytopenia Study (HAT) investigators
    • Greinacher A, Janssens U, Berg G, et al: Lepirudin (recombinant hirudin) for parenteral anticoagulation in patients with heparin-induced thrombocytopenia. Heparin-Associated Thrombocytopenia Study (HAT) investigators. Circulation 1999, 100:587-593.
    • (1999) Circulation , vol.100 , pp. 587-593
    • Greinacher, A.1    Janssens, U.2    Berg, G.3
  • 38
    • 0345369740 scopus 로고    scopus 로고
    • Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia: A prospective study
    • Greinacher A, Volpel H, Janssens U, et al: Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia: a prospective study. Circulation 1999, 99:73-80.
    • (1999) Circulation , vol.99 , pp. 73-80
    • Greinacher, A.1    Volpel, H.2    Janssens, U.3
  • 39
    • 0034254793 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia with thromboembolic complications: Meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range
    • Greinacher A, Eichler P, Lubenow N, Kwasny H, Luz M: Heparin-induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range. Blood 2000, 96:846-851.
    • (2000) Blood , vol.96 , pp. 846-851
    • Greinacher, A.1    Eichler, P.2    Lubenow, N.3    Kwasny, H.4    Luz, M.5
  • 40
    • 0035836541 scopus 로고    scopus 로고
    • Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia
    • for the ARG-911 Study Investigators
    • Lewis BE, Wallis DE, Berkowitz SD, for the ARG-911 Study Investigators: Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation 2001, 103:1838-1843.
    • (2001) Circulation , vol.103 , pp. 1838-1843
    • Lewis, B.E.1    Wallis, D.E.2    Berkowitz, S.D.3
  • 41
    • 0035167688 scopus 로고    scopus 로고
    • Prospective randomised open-label comparison of danaparoid with dextran 70 in the treatment of heparin-induced thrombocytopaenia with thrombosis: A clinical outcome study
    • for the Australian HIT Study Group
    • Chong BH, Gallus AS, Cade JF, for the Australian HIT Study Group: Prospective randomised open-label comparison of danaparoid with dextran 70 in the treatment of heparin-induced thrombocytopaenia with thrombosis: a clinical outcome study. Thromb Haemost 2001, 86:1170-1175.
    • (2001) Thromb. Haemost. , vol.86 , pp. 1170-1175
    • Chong, B.H.1    Gallus, A.S.2    Cade, J.F.3
  • 43
    • 0026515273 scopus 로고
    • Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis
    • Ortel TL, Gockerman JP, Califf RM, et al: Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis. Thromb Haemost 1992, 67:292-296.
    • (1992) Thromb. Haemost. , vol.67 , pp. 292-296
    • Ortel, T.L.1    Gockerman, J.P.2    Califf, R.M.3
  • 44
    • 0031793581 scopus 로고    scopus 로고
    • New treatment options for heparin-induced thrombocytopenia
    • Ortel TL, Chong BH: New treatment options for heparin-induced thrombocytopenia. Sem Hematol 1998, 35(Suppl. 5):26-34.
    • (1998) Sem. Hematol. , vol.35 , Issue.SUPPL. 5 , pp. 26-34
    • Ortel, T.L.1    Chong, B.H.2
  • 45
    • 8644253626 scopus 로고    scopus 로고
    • Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: An analysis of 3 prospective studies
    • Lubenow N, Eichler P, Lietz T, Farner B, Greinacher A: Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies. Blood 2004, 104:3072-3077.
    • (2004) Blood , vol.104 , pp. 3072-3077
    • Lubenow, N.1    Eichler, P.2    Lietz, T.3    Farner, B.4    Greinacher, A.5
  • 46
    • 0034966778 scopus 로고    scopus 로고
    • A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia
    • Farner B, Eichler P, Kroll H, Greinacher A: A comparison of danaparoid and lepirudin in heparin-induced thrombocytopenia. Thromb Haemost 2001, 85:950-957.
    • (2001) Thromb. Haemost. , vol.85 , pp. 950-957
    • Farner, B.1    Eichler, P.2    Kroll, H.3    Greinacher, A.4
  • 47
    • 1242297625 scopus 로고    scopus 로고
    • Treatment of heparin-induced thrombocytopenia: A critical review
    • Hirsh J, Heddle N, Kelton JG: Treatment of heparin-induced thrombocytopenia: a critical review. Arch Intern Med 2004, 91:361-369.
    • (2004) Arch. Intern. Med. , vol.91 , pp. 361-369
    • Hirsh, J.1    Heddle, N.2    Kelton, J.G.3
  • 48
    • 1642317572 scopus 로고    scopus 로고
    • Effect of direct thrombin inhibitors, bivalirudin, lepirudin, and argatroban, on prothrombin time and INR values
    • Gosselin RC, Dager WE, King JH, et al: Effect of direct thrombin inhibitors, bivalirudin, lepirudin, and argatroban, on prothrombin time and INR values. Am J Clin Pathol 2004, 121:593-599.
    • (2004) Am. J. Clin. Pathol. , vol.121 , pp. 593-599
    • Gosselin, R.C.1    Dager, W.E.2    King, J.H.3
  • 49
    • 0035082406 scopus 로고    scopus 로고
    • Interpreting the international normalized ratio (INR) in individuals receiving argatroban and warfarin
    • Sheth SB, DiCicco RA, Hursting MJ, Montague T, Jorkasky DK: Interpreting the international normalized ratio (INR) in individuals receiving argatroban and warfarin. Thromb Haemost 2001, 85:435-440.
    • (2001) Thromb. Haemost. , vol.85 , pp. 435-440
    • Sheth, S.B.1    DiCicco, R.A.2    Hursting, M.J.3    Montague, T.4    Jorkasky, D.K.5
  • 50
    • 22544466120 scopus 로고    scopus 로고
    • Transitioning from argatroban to warfarin therapy in patients with heparin-induced thrombocytopenia
    • Hursting MJ, Lewis BE, Macfarlane DE: Transitioning from argatroban to warfarin therapy in patients with heparin-induced thrombocytopenia. Clin Appl Thromb Hemost 2005, 11:279-287.
    • (2005) Clin. Appl. Thromb. Hemost. , vol.11 , pp. 279-287
    • Hursting, M.J.1    Lewis, B.E.2    Macfarlane, D.E.3
  • 51
    • 19944429124 scopus 로고    scopus 로고
    • Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: A blinded comparative multicenter study with unfractioned heparin
    • Savi P, Chong BH, Greinacher A, et al: Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractioned heparin. Blood 2005, 105:139-144.
    • (2005) Blood , vol.105 , pp. 139-144
    • Savi, P.1    Chong, B.H.2    Greinacher, A.3
  • 52
    • 3943089715 scopus 로고    scopus 로고
    • Treatment of heparin-induced thrombocytopenia with fondaparinux
    • Harenberg J, Jorg I, Fenyvesi T: Treatment of heparin-induced thrombocytopenia with fondaparinux. Haematologica 2005, 89:1017-1018.
    • (2005) Haematologica , vol.89 , pp. 1017-1018
    • Harenberg, J.1    Jorg, I.2    Fenyvesi, T.3
  • 53
    • 18844385757 scopus 로고    scopus 로고
    • Successful treatment of heparin induced thrombocytopenia (HIT) with fondaparinux
    • Kuo KHM, Kovacs MJ: Successful treatment of heparin induced thrombocytopenia (HIT) with fondaparinux. Thromb Haemost 2005, 93:999-100.
    • (2005) Thromb. Haemost. , vol.93 , pp. 999-1100
    • Kuo, K.H.M.1    Kovacs, M.J.2


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