Review article: The management of heartburn in pregnancy

Alimentary Pharmacology and Therapeutics

Volumn 22, Issue 9, 2005, Pages 749-757

  Richter, J E ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; ALUMINUM HYDROXIDE; ANTACID AGENT; BICARBONATE; CALCIUM CARBONATE; CIMETIDINE; CISAPRIDE; DIAZEPAM; ESOMEPRAZOLE; FAMOTIDINE; GAVISCON; HISTAMINE H2 RECEPTOR ANTAGONIST; IRON; LANSOPRAZOLE; MAGNESIUM SULFATE; MAGNESIUM TRISILICATE; METOCLOPRAMIDE; MIDAZOLAM; NIZATIDINE; OMEPRAZOLE; PANTOPRAZOLE; PETHIDINE; PLACEBO; PROPOFOL; PROTON PUMP INHIBITOR; RABEPRAZOLE; RANITIDINE; SUCRALFATE;

ANENCEPHALUS; BIRTH DEFECT; BREAST MILK; CARDIOVASCULAR DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; CONGENITAL MALFORMATION; CRYPTORCHISM; DIET; DRUG ABSORPTION; DRUG CLASSIFICATION; DRUG CONTRAINDICATION; DRUG SAFETY; EMBRYOTOXICITY; FETOTOXICITY; FETUS DISTRESS; FETUS MALFORMATION; GASTROESOPHAGEAL REFLUX; HEART ARRHYTHMIA; HEART ATRIUM SEPTUM DEFECT; HEARTBURN; HUMAN; HYDROCEPHALUS; INFERTILITY; LACTATION; LIFESTYLE; METABOLIC ACIDOSIS; METABOLIC ALKALOSIS; MUSCLE HYPOTONIA; NAUSEA; NEPHROLITHIASIS; NONHUMAN; PATHOGENESIS; PREGNANCY; PRESCRIPTION; PRIORITY JOURNAL; RESPIRATORY DISTRESS; REVIEW; SYMPTOM; TERATOGENICITY; VOMITING;

ANTACIDS; ANTI-ULCER AGENTS; CISAPRIDE; FEMALE; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL MOTILITY; HEARTBURN; HISTAMINE H2 ANTAGONISTS; HUMANS; LACTATION; METOCLOPRAMIDE; PREGNANCY; PREGNANCY COMPLICATIONS; PROTON PUMPS; SUCRALFATE;

EID: 27644552210     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2005.02654.x     Document Type: Review

References (47)

1. Richter JE. Gastroesophageal reflux disease during pregnancy. Gastroenterol Clin North Am 2003; 32: 235-61.
2. deCastro LP. Reflux esophagitis as the cause of heartburn in pregnancy. Am J Obstet Gynecol 1967; 98: 1-10.
3. Marrero JM, Goggins PM, de Caestecker JS, et al. Determinants of pregnancy heartburn. Br J Obstet Gynaecol 1992; 99: 731-4.
4. Fisher RS, Robert GS, Grabowski CJ, et al. Altered lower esophageal sphincter function during early pregnancy. Gastroenterology 1978; 74: 1233-7.
5. VanThiel DH, Gavaler JS, Joshi SN, et al. Heartburn of pregnancy. Gastroenterology 1977; 72: 668-78.
6. Klauser AG, Schindlbeck NE, Muller-Lissner SA. Symptoms in gastroesophageal reflux disease. Lancet 1990; 335: 265-8.
7. Capell MS, Colon VJ, Sidhom OA. A study of eight medical centers on the safety and efficacy of EGD in 83 pregnant females with follow up of fetal outcomes and with comparison to control groups. Am J Gastroenterol 1996; 91: 348-54.
8. ASGE Guideline. Guideline for endoscopy in pregnant and lactating women. Gastrointest Endosc 2005; 61: 357-62.
9. Broussard SN, Richter JE. Treating gastro-oesophageal reflux disease during pregnancy and lactation. What are the safest therapy options? Drug Saf 1998; 4: 325-7.
10. Niebyl JR. Teratology and drug use during pregnancy and lactation. In: Scott, JR, Isaia, PD, Hammond, C, eds. Danforth's Obstetrics and Gynecology, 7th edn. Philadelphia, USA: WB Saunders, 1994:225-44.
11. Lewis JH, Weingold AB. The committee on FDA-related matters for the American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol 1985; 80: 912-23.
12. Ching C, Lam S. Antacids: indications and limitations. Drugs 1994; 47: 305-17.
13. Witten FP, King TM, Blake O. The effects of chronic gastrointestinal medications on the fetus and neonate. Obstet Gynecol 1981; 58 (Suppl. 5): 79-84.
14. Tytgat GN, Heading RC, Muller-Lissner S, et al. Contemporary understanding and management of reflux and constipation in the general population and pregnancy: a consensus meeting. Aliment Pharmacol Ther 2003; 18: 291-301.
15. Lindow SW, Regnell P, Sykes J, Little S. An open-label multicenter study to assess the safety and efficacy of a novel reflux supplement (Gaviscon advance) in the treatment of heartburn of pregnancy. Int J Clin Pract 2003; 57: 175-9.
16. Briggs GG, Freeman RY, Yaffe SJ. Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk. Baltimore, USA: William and Wilkins, 2002.
17. Ranchet G, Gangemi O, Petrone M. Sucralfate in the treatment of gravid pyrosis. G Ital Obstet Ginecol 1990; 12: 1-16.
18. Berkovich M, Elbirt D, Addis A, et al. Fetal effects of metoclopramide therapy for nausea and vomiting of pregnancy. N Engl J Med 2000; 343: 445-6.
19. Propulsid (product information). Titusville, NJ, USA: Janssen Pharmaceutical, 2000.
20. Bailey B, Addis A, Lee A, et al. Cisapride use during human pregnancy. A prospective controlled multi-center study. Dig Dis Sci 1997; 42: 1848-52.
21. Wilton LV, Pearce GL, Martin RM, et al. The outcomes of pregnancy in women exposed to newly marketed drugs in general practice in England. Br J Obstet Gynaecol 1998; 105: 882-9.
22. Wysowski DK, Corken A, Gallo-Torres A, et al. Post-marketing reports of QT prolongation and ventricular arrhythmias in association with cisapride and FDA regulatory actions. Am J Gastroenterol 2001; 96: 1689-703.
23. Larson JD, Patatanian E, Miner PB, et al. Double-blind, placebo-controlled study of ranitidine for gastroesophageal reflux symptoms during pregnancy. Obstet Gynecol 1997; 90: 83-7.
24. Finkelstein W, Isselbacker KJ. Cimetidine. N Engl J Med 1978; 229: 992-6.
25. Parker S, Schade RR, Pohl CR, et al. Prenatal and neonatal exposure of male pups to cimetidine but not ranitidine adversely affects subsequent adult sexual function. Gastroenterology 1984; 86: 675-80.
26. 2 blockers. A prospective cohort study. Dig Dis Sci 1996; 41: 1145-9.
27. Kalle B. Delivery outcomes after the use of acid-suppressing drugs in early pregnancy with special reference to omeprazole. Br J Obstet Gynaecol 1998; 105: 877-83.
28. Ruigomez A, Rodriguez LAG, Cattaruzzi C, et al. Use of cimetidine, omeprazole and ranitidine in pregnant women and pregnancy outcomes. Am J Epidemiol 1999; 150: 476-81.
29. Smallwood RA, Berlin RG, Catagnoli N, et al. Safety of acid suppressing drugs. Dig Dis Sci 1995; 40 (Suppl.): 635-8.
30. Savarino V, Giasti M, Scalabrini P, et al. Famotidine has no significant effect on gonadal function in men. Gastroenterol Clin Biol 1988; 12: 19-22.
31. Morton DM. Pharmacology and toxicity of nizatidine. Scand J Gastroenterol 1987; 22 (Suppl. 136): 1-8.
32. 2 receptor antagonist, nizatidine, in the male rat. Toxicol Appl Pharmacol 1990; 102: 219-32.
33. Prilosec (product information). Wilmington, DE, USA: Astra-Zeneca, 2004.
34. Harper MA, McVeigh JE, Thompson W, et al. Successful pregnancy in association with Zollinger-Ellison syndrome. Am J Obstet Gynecol 1995; 173: 863-4.
35. Brunner G, Meyer H, Athmann C. Omeprazole for peptic ulcer disease in pregnancy. Digestion 1998; 59: 651-4.
36. Nikfar S, Abdollahi M, Moretti ME, et al. Use of proton pump inhibitors during pregnancy and rates of major malformations. A meta-analysis. Dig Dis Sci 2002; 47: 1526-9.
37. Nielsen GL, Sorensen HT, Thulctrup AM, et al. The safety of proton pump inhibitors in pregnancy. Aliment Pharmacol Ther 1999; 13: 1085-9.
38. Larkin A, Loebstein R, Addis A, et al. The safety of omeprazole during pregnancy: a multicenter prospective controlled study group. Am J Obstet Gynecol 1998; 179: 727-30.
39. Prevacid (product information). Lake Forest, IL, USA: TAP Pharmaceutical, 2005.
40. Diav-Citrin O, Arnon J, Shechtman S, et al. The safety of proton pump inhibitors in pregnancy: a multicenter prospective controlled study. Aliment Pharmacol Ther 2005; 21: 269-75.
41. Somogyi A, Gugler R. Cimetidine excretion in breast milk. Br J Clin Pharmacol 1979; 7: 627-9.
42. Courtney TP, Shaw RW, Cedar E, et al. Excretion of famotidine in breast milk. Br J Clin Pharmacol 1988; 26: 639.
43. Obermeyer BD, Bergstrom PF, Callagher JT, et al. Secretion of nizatidine into human breast milk after single and multiple doses. Clin Pharmacol Ther 1990; 47: 724-30.
44. Physician's Desk Reference, 58th edn. Montvale, NJ, USA: Medical Economics, 2002.
45. Committee on Drugs. American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 1994; 93: 137-50.
46. Marshall JK, Thompson ABR, Armstrong D. Omeprazole for refractory gastroesophageal reflux disease during pregnancy and lactation. Can J Gastroenterol 1998; 12: 225-7.
47. Rabeprazole (product information). Teaneck, NJ, USA: Eisai, 2004.