Photodynamic therapy with zinc-tetra(p-sulfophenyl)porphyrin bound to cyclodextrin induces single strand breaks of cellular DNA in G361 melanoma cells

Toxicology in Vitro

Volumn 19, Issue 7, 2005, Pages 971-974

  Kolarova, H ^a   Macecek, J ^a   Nevrelova, P ^a   Huf, M ^a   Tomecka, M ^a   Bajgar, R ^a   Mosinger, J ^b   Strnad, M ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Comet assay; Light; Phototoxicity; Sensitizers

Indexed keywords

CELL DNA; CYCLODEXTRIN; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG; ZINC TETRAKIS(4 SULFOPHENYL)PORPHYRIN;

CANCER CELL; CELL CULTURE; COMET ASSAY; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; HUMAN; HUMAN CELL; MELANOMA; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; TUMOR CELL;

BETA-CYCLODEXTRINS; CELL LINE, TUMOR; COMET ASSAY; DNA DAMAGE; DNA, SINGLE-STRANDED; HUMANS; LIGHT; MELANOMA; METALLOPORPHYRINS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; TIME FACTORS;

EID: 27644551029     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.06.015     Document Type: Conference Paper

References (14)

1. R.R. Allison, G.H. Downie, R. Cuenca, X.H. Hu, C.J.H. Childs, and C.H. Sibata Photosensitizers in clinical PDT Photodiagnosis and Photodynamic Therapy 1 2004 27 42
2. J. Dahle, H.B. Steen, and J. Moan The mode of cells death induced by photodynamic treatment depends on cell density Journal of Photochemistry and Photobiology B: Biology 70 3 1999 363 367
3. T.J. Dougherty Photodynamic therapy Photochemistry and Photobiology 58 1993 895 900
4. M.H.L. Green, J.E. Lowe, C.A. Delaney, and I.C. Green Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells Methods in Enzymology 269 1996 243 266
5. D. Kessel, and Y. Luo Initiation of apoptosis versus necrosis by photodynamic therapy with chloroaluminium phtalocyanine Photochemistry and Photobiology 4 1997 66 74
6. D. Kessel Photodynamic therapy: from beginning Photodiagnosis and Photodynamic Therapy 1 2004 3 7
7. H. Kolarova, J. Mosinger, R. Lenobel, K. Kejlová, D. Jírová, and M. Strnad In vitro toxicity testing of supramolecular sensitizers for photodynamic therapy Toxicology In Vitro 17 5-6 2003 775 778
8. A.C.E. Moor Signaling pathways in cell death and survival after photodynamic therapy Journal of Photochemistry and Photobiology B: Biology 57 2000 1 13
9. J. Mosinger, M. Deumié, J. Lang, P. Kubát, and D.M. Wagnerová Supramolecular sensitizer: complexation of meso tetrakis(4 sulfonatophenyl) porphyrin with 2-hydroxypropyl-cyclodextrins Journal of Photochemistry and Photobiology A: Chemistry 130 2000 13 20
10. J. Mosinger, V. Kliment, J. Sejbal, P. Kubát, and K. Lang Host-guest complexes of anionic porphyrin sensitizers with cyclodextrins Journal of Porphyrins and Phthalocyanines 6 7-8 2002 514 526
11. E.S. Nyman, and P.H. Hynninen Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy Journal of Photochemistry and Photobiology B 73 1-2 2004 1 28
12. N.L. Oleinick, and H.H. Evans The photobiology of photodynamic therapy: cellular targets and mechanisms Radiation Research 150 1998 S146 S156
13. M.P. Piperakis, E.E. Visvardis, and A.M. Tassiou Comet assay for nuclear DNA damage Methods in Enzymology 269 20 1999 184 194
14. C. Sibata, V.C. Conlussi, N.L. Oleinick, and T.J. Kinsella Photodynamic therapy in oncology Expert Opinion in Pharmacotherapy 2 6 2001 917 927