Update on the evaluation of pancreatic exocrine status in cystic fibrosis

Current Opinion in Pulmonary Medicine

Volumn 11, Issue 6, 2005, Pages 524-527

  Borowitz, Drucy ^a,b  

^a UNIVERSITY AT BUFFALO   (United States)

^b CHILDREN S HOSPITAL OF BUFFALO   (United States)

Author keywords

Breath tests; Cystic fibrosis; Fecal chymotrypsin; Fecal elastase; Fecal lipase; Pancreatic function; Pancreatic insufficiency; Pancreatic sufficiency

Indexed keywords

CARBON 13; CHYMOTRYPSIN; ELASTASE; PANCREAS ENZYME; TRIACYLGLYCEROL LIPASE;

BREATH ANALYSIS; CHRONIC PANCREATITIS; CLINICAL FEATURE; CYSTIC FIBROSIS; HUMAN; PANCREAS FUNCTION; PANCREAS INSUFFICIENCY; PANCREAS SECRETION; PREDICTION AND FORECASTING; REVIEW; SENSITIVITY AND SPECIFICITY;

EID: 27644550517     PISSN: 10705287     EISSN: 15316971     Source Type: Journal    
DOI: 10.1097/01.mcp.0000181474.08058.b3     Document Type: Review

References (15)

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4. Walkowiak J, Nousia-Arvanitakis S, Henker J, et al. Indirect pancreatic function tests in children. J Pediatr Gastroenterol Nutr 2005; 40:107-114. This is an excellent review of pancreatic function tests in children with a comparison of the pros and cons of each test and an algorithm for assessment of pancreatic exocrine function.
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11. Walkowiak J, Nousia-Arvanitakis S, Lisowska A, et al. Serum lipase after secretin stimulation detects mild pancreatic involvement in cystic fibrosis. J Pediatr Gastroenterol Nutr 2004; 38:430-435.
12. Baker SS, Borowitz D, Duffy L, et al. Pancreatic enzyme therapy and clinical outcomes in patients with cystic fibrosis. J Pediatr 2005; 146:189-193. This cross-sectional analysis describes the discordance between pancreatic functional status based on FE-1 and growth or symptoms. It also describes the lack of concordance between patients' self-described gastrointestinal symptoms and enzyme dose.
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