Long-term effects of cyclosporine in children with idiopathic nephrotic syndrome: A single-centre experience

Nephrology Dialysis Transplantation

Volumn 20, Issue 11, 2005, Pages 2433-2438

  El Husseini, Amr ^a   El Basuony, Fathy ^a   Mahmoud, Ihab ^a   Sheashaa, Hussein ^a   Sabry, Alaa ^a   Hassan, Rashad ^a   Taha, Nohir ^a   Hassan, Nabil ^a   Sayed Ahmad, Nagy ^a   Sobh, Mohamed A ^a  

^a MANSOURA UNIVERSITY   (Egypt)

Author keywords

Cyclosporine; Long term; Nephrotic syndrome; Pathology; Treatment

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; KETOCONAZOLE; PREDNISOLONE;

ADOLESCENT; ADULT; AGE; ARTICLE; ATROPHY; BODY SURFACE; CHILD; CHRONIC KIDNEY FAILURE; CLINICAL OBSERVATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG INDICATION; DRUG WITHDRAWAL; FEMALE; FOCAL GLOMERULOSCLEROSIS; GINGIVA HYPERPLASIA; HUMAN; HYPERTENSION; HYPERTRICHOSIS; KIDNEY BIOPSY; KIDNEY DYSFUNCTION; KIDNEY FIBROSIS; KIDNEY INTERSTITIUM; KIDNEY TUBULE; LONG TERM CARE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MINIMAL CHANGE GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROTEINURIA; RECURRENCE RISK; REMISSION;

ADOLESCENT; BIOPSY; CHILD; CHILD, PRESCHOOL; CYCLOSPORINE; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; MALE; NEPHROTIC SYNDROME; PREDNISOLONE; REMISSION INDUCTION; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 27644545854     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfi059     Document Type: Article

References (27)

1. Seikaly MG, Prashner H, Nolde-Hurlbert B, Browne R. Long-term clinical and pathological effects of cyclosporine in children with nephrosis. Pediatr Nephrol 2000; 14: 214-217
2. Hodson EM, Knight JF, Willis NS, Craig JC. Corticosteroid therapy for nephrotic syndrome in children. Cochrane Database Syst Rev 2003; 1: CD001533
3. Ponticelli C, Edefonti A, Ghio L et al. Cyclosporine versus cyclophosphamide for patients with steroid-dependent and frequently relapsing nephrotic syndrome: A multicenter randomized controlled trial. Nephrol Dial Transplant 1993; 8: 1326-1332
4. Takeda A. Takimoto H, Mizusawa Y, Simoda M. Prediction of subsequent relapse in children with steroid-sensitive nephrotic syndrome. Pediatr Nephrol 2001; 16: 888-893
5. Klinika B, Kaczmarczyk I, Radziszewski A, Sulowicz W. Use of cyclosporine A and new immunosuppressive drugs in the therapy of glomerulonephritis. Przegl Lek 2001; 58: 798-804
6. Klein M, Radhakrishnan J, Appel G. Cyclosporine treatment of glomerular diseases. Annu Rev Med 1999; 50: 1-15
7. Kemper MJ, Kuwertz-Broeking E, Bulla M, Mueller-Wiefel DE, Neuhaus TJ. Recurrence of severe steroid dependency in cyclosporine A-treated childhood idiopathic nephrotic syndrome. Nephrol Dial Transplant 2004; 19: 1136-1141
8. Xia ZK, Liu GL, Gao YF et al. Cyclosporine A treatment of 83 children with nephrotic syndrome of different pathological types. Zhonghua Er Ke Za Zhi 2003; 41: 813-816
9. Hino S, Takemura T, Okada M et al. Follow-up study of children with nephrotic syndrome treated with a long-term moderate dose of cyclosporine. Am J of Kidney Disease 1998; 31: 932-939
10. Inoue Y, Ijima K, Nakamura H, Yoshikaw N. Two-year cyclosporine treatment in children with steroid-dependent nephrotic syndrome. Pediatr Nephrol 1999; 13: 33-38
11. Seikaly M, Prashner H, Nolde-Hurlbert B, Browne R. Long-term clinical and pathological effects of cyclosporine in children with nephrosis. Pediatr Nephrol 2000; 14: 214-217
12. Ghiggeri GM, Catarsi P, Scolari F et al. Cyclosporine in patients with steroid-resistant nephrotic syndrome: An open-label, nonrandomized, retrospective study. Clin Ther 2004; 26: 1411-1418
13. International Study of Kidney Disease in Children. The primary nephrotic syndrome in children: Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. J Pediatr 1981; 98: 561-564
14. Mihatsch M, Antonovych T, Bohman S-O et al. Cyclosporine nephropathy: standardization of the evaluation of kidney biopsies. Clin Nephrol 1994; 41: 23-32
15. Everitt BS. Statistical methods for medical investigators, 2nd Edn. New York: John Wiley and Sons Inc., 1994
16. Filler G. Treatment of nephrotic syndrome in children and controlled trials. Nephrol Dial Transplant 2003; 18: 75-78
17. Tohjoh S, Narita M, Koyama T. Clinical evaluation of cyclosporine in the treatment of nephrotic syndrome: Multicenter double blind study (in Japanese). Jin To Tohseki 1994; 37: 565-608
18. Meyrier A. Use of cyclosporine in the treatment of idiopathic nephrotic syndrome in adults. Contrib Nephrol 1995; 114: 28-48
19. Heering P, Braun N, Mullejans R et al. Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis. Am J Kidney Dis 2004; 43: 10-18
20. Tarshish P, Tobin JN, Bernstein J, Edelmann CM Jr. Cyclophosphamide does not benefit patients with focal segmental glomerulosclerosis. Pediatr Nephrol 1996; 10: 590-593
21. Niaudet P, Habib R. Cyclosporine in the treatment of idiopathic nephrosis. J Am Soc Nephrol 1994; 5: 1049-1056
22. Niaudet P and French Society of Pediatric Nephrology. Treatment of childhood steroid-resistant idiopathic nephrosis with a combination of cyclosporine and prednisone. J Pediatr 1994; 125: 981-986
23. Hymes LC. Steroid-resistant, cyclosporine-responsive, relapsing nephrotic syndrome. Pediatr Nephrol 1995; 9: 137-139
24. Habashy D, Hodson EM, Craig JC. Interventions for steroid-resistant nephrotic syndrome: A systematic review. Pediatr Nephrol 2003; 18: 906-912
25. Sairam V, Kalia A, Rajaraman S, Travis L. Secondary resistance to cyclosporine A in children with nephrotic syndrome. Pediatr Nephrol 2002; 17: 842-846
26. Habib R, Niaudet P. Comparison between pre and post-treatment renal biopsies in children receiving cyclosporine for idiopathic nephrosis. Clin Nephrol 1994; 42: 141-146
27. El-Husseini A, El-Basuony F, Donia A et al. Concomitant administration of cyclosporine and ketoconazole in idiopathic nephrotic syndrome. Nephrol Dial Transplant 2004; 19: 2266-2271