Diabetogenic effects and pancreatic oxidative damage in rats subchronically exposed to arsenite

Toxicology Letters

Volumn 160, Issue 2, 2006, Pages 135-142

  Izquierdo Vega, Jeannett A ^a   Soto, Claudia A ^b   Sanchez Peña, Luz C ^a   De Vizcaya Ruiz, Andrea ^a   Del Razo, Luz M ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

Author keywords

Arsenic; Arsenic metabolism; Diabetes mellitus; Insulin resistance; Oxidative stress

Indexed keywords

ARSENIC TRIOXIDE; ARSENITE SODIUM; GLUTATHIONE; THIOREDOXIN REDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETOGENESIS; ENZYME ACTIVITY; EVALUATION; HOMEOSTASIS; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN SENSITIVITY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PANCREAS; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

ANIMALS; ARSENITES; BLOOD GLUCOSE; ENZYME INHIBITORS; GLUCAGON; GLUTATHIONE; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; LIPID PEROXIDATION; MALE; MODELS, ANIMAL; OXIDATIVE STRESS; PANCREAS; RATS; RATS, WISTAR; SODIUM COMPOUNDS; THIOREDOXIN REDUCTASE (NADPH);

ANIMALIA; RATTUS NORVEGICUS;

EID: 27644530879     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.06.018     Document Type: Article

References (37)

1. E. Beutler, O. Duron, and B.M. Kelly Improved method for the determination of blood glutathione J. Lab. Clin. Med. 61 1963 882 888
2. E. Bonora, G. Targher, M. Alberiche, G. Formentini, F. Calcaterra, S. Lombardi, F. Marini, M. Poli, L. Zenari, A. Raffaelli, S. Perbellini, M.B. Zenere, F. Saggiani, R.C. Bonadonna, and M. Muggeo Predictors of insulin sensitivity in Type 2 diabetes mellitus Diab. Med. 19 2002 535 542
3. E. Brambila, W. Achanzar, W. Qu, M. Webber, and M. Waalkes Chronic arsenic-exposed human prostate epithelial cells exhibit stable arsenic tolerance: mechanistic implications of altered cellular glutathione and glutathione S-transferase Toxicol. Appl. Pharmacol. 183 2002 99 107
4. J.A. Buege, and S.D. Aust Microsomal lipid peroxidation Meth. Enzymol. 52 1978 302 310
5. L.M. Del Razo, B. Quintanilla-Vega, E. Brambila-Colombres, E.S. Calderon-Aranda, M. Manno, and A. Albores Stress proteins induced by arsenic Toxicol. Appl. Pharmacol. 177 2001 132 148
6. J.L. Evans, I.D. Goldfine, B.A. Maddux, and G.M. Grodsky Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction? Diabetes 52 2003 1 8
7. S. Flora Arsenic-induced oxidative stress and its reversibility following combined administration of N-acetylcysteine and meso 2,3-dimercaptosuccinic acid in rats Clin. Exp. Pharmacol. Physiol. 26 1999 865 869
8. J.F. Holson, D.G. Stump, K.J. Clevidence, J.F. Knapp, and C.H. Farr Evaluation of the prenatal developmental toxicity of orally administered arsenic trioxide in rats Food Chem. Toxicol. 38 2000 459 466
9. S.M. Hsu, and L. Raine Protein A, avidin, and biotin in immunohistochemistry J. Histochem. Cytochem. 29 1981 1349 1353
10. M.F. Hughes, L.M. Del Razo, and E.M. Kenyon Dose-dependent effects on tissue distribution and metabolism of dimethylarsinic acid in the mouse after intravenous administration Toxicology 143 2000 155 166
11. R.C. Kaltreider, A.M. Davis, J.P. Lariviere, and J.W. Hamilton Arsenic alters the function of the glucocorticoid receptor as a transcription factor Environ. Health Perspect. 109 2001 245 251
12. R. Legro, D. Finegood, and A. Dunaif A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 83 1998 2694 2698
13. S. Lin, L.M. Del Razo, M. Styblo, C. Wang, W.R. Cullen, and D.J. Thomas Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes Chem. Res. Toxicol. 14 2001 305 311
14. D.E. Moller, and K.D. Kaufman Metabolic syndrome: a clinical and molecular perspective Annu. Rev. Med. 56 2005 45 62
15. NRC (National Research Council), 2001. Arsenic in Drinking Water: 2001 Update, Washington, DC. National Academy Press, pp. 284-232.
16. D. Nandi, R.C. Patra, and D. Swarup Effect of cysteine, methionine, ascorbic acid and thiamine on arsenic-induced oxidative stress and biochemical alterations in rats Toxicology 211 2005 26 35
17. M. Nikaido, J. Pi, Y. Kumagai, H. Yamauchi, K. Taguchi, S. Horiguchi, Y. Sun, G. Sun, and N. Shimojo Decreased enzyme activity of hepatic thioredoxin reductase and glutathione reductase in rabbits by prolonged exposure to inorganic arsenate Environ. Toxicol. 18 2003 306 311
18. J. Nordberg, and E.S. Arner Reactive oxygen species, antioxidants, and the mammalian thioredoxin system Free Rad. Biol. Med. 31 2001 1287 1312
19. J. Pi, H. Yamauchi, Y. Kumagai, G. Sun, T. Yoshida, H. Aikawa, C. Hopenhayn-Rich, and N. Shimojo Evidence for induction of oxidative stress caused by chronic exposure of chinese residents to arsenic contained in drinking water Environ. Health Perspect. 110 2002 331 336
20. P.T. Pisciotto, and J.H. Graziano Induction of mucosal glutathione synthesis by arsenic Biochim. Biophys. Acta 628 1980 241 243
21. M. Rahman, and O. Axelson Diabetes mellitus and arsenic exposure: a second look at case-control data from a Swedish copper smelter Occup. Environ. Med. 52 1995 773 774
22. M. Rahman, G. Wingren, and O. Axelson Diabetes mellitus among Swedish art glassworkers: an effect of arsenic exposure? Scand. J. Work Environ. Health 22 1995 146 149
23. V.M. Rodriguez, M.E. Jimenez-Capdeville, and M. Giordano The effects of arsenic exposure on the nervous system Toxicol. Lett. 145 2003 1 18
24. A. Rudich, A. Tirosh, R. Potashnik, R. Hemi, H. Kanety, and N. Bashan Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes Diabetes 47 1998 1562 1569
25. S. Samuel, R. Kathirvel, T. Jayavelu, and P. Chinnakkannu Protein oxidative damage in arsenic induced rat brain: influence of DL-alpha-lipoic acid Toxicol. Lett. 155 2005 27 34
26. P.C. Schulze, J. Yoshioka, T. Takahashi, Z. He, G.L. King, and R.T. Lee Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein J. Biol. Chem. 279 2004 30369 30374
27. A.D. Smith, and O.A. Levander High-throughput 96-well microplate assays for determining specific activities of glutathione peroxidase and thioredoxin reductase Meth. Enzymol. 347 2002 113 121
28. M. Styblo, and D. Thomas Binding of arsenicals to proteins in an in vitro methylation system Toxicol. Appl. Pharmacol. 147 1997 1 8
29. V. Thirunavukkarasu, A.t. Anitha Nandhini, and C.V. Anuradha Lipoic acid attenuates hypertension and improves insulin sensitivity, kallikrein activity and nitrite levels in high fructose-fed rats J. Comp. Physiol. B 174 2004 587 592
30. D.J. Thomas, S.B. Waters, and M. Styblo Elucidating the pathway for arsenic methylation Toxicol. Appl. Pharmacol. 198 2004 319 326
31. S.-M. Tsai, T.-N. Wang, and Y.-C. Ko Mortality for certain diseases in areas with high levels of arsenic in drinking water Arch. Environ. Health 54 1999 186 200
32. C.H. Tseng, T.Y. Tai, C.K. Chong, C.P. Tseng, M.S. Lai, B.J. Lin, H.Y. Chiou, Y.M. Hsueh, K.H. Hsu, and C.J. Chen Long-term arsenic exposure and incidence of non-insulin-dependent diabetes mellitus: a cohort study in arseniasis-hyperendemic villages in Taiwan Environ. Health Perspect. 108 2000 847 851
33. C.H. Tseng An overview on peripheral vascular disease in blackfoot disease-hyperendemic villages in Taiwan Angiology 53 2002 529 537
34. C.H. Tseng The potential biological mechanisms of arsenic-induced diabetes mellitus Toxicol. Appl. Pharmacol. 197 2004 67 83
35. F.S. Walton, A.W. Harmon, D.S. Paul, Z. Drobna, Y.M. Patel, and M. Styblo Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes Toxicol. Appl. Pharmacol. 198 2004 424 433
36. 3 in rabbits: evidence of reversible chronic toxicity and tissue accumulation of arsenicals after parenteral administration Toxicol. Appl. Pharmacol. 189 2003 214 220
37. K. Yamanaka, F. Takabayashi, M. Mizoi, Y. An, A. Hasegawa, and S. Okada Oral exposure of dimethylarsinic acid, a main metabolite of inorganic arsenics, in mice leads to an increase in 8-Oxo-2′-deoxyguanosine level, specifically in the target organs for arsenic carcinogenesis Biochem. Biophys. Res. Commun. 287 2001 66 70