Short-term administration of a new free radical scavenger, edaravone, is more effective than its long-term administration for the treatment of neonatal hypoxic-ischemic encephalopathy

Stroke

Volumn 36, Issue 11, 2005, Pages 2468-2474

  Noor, Jesmin I ^a   Ikeda, Tomoaki ^a   Mishima, Kenichi ^b   Aoo, Naoya ^b   Ohta, Sumie ^b   Egashira, Nobuaki ^b   Iwasaki, Katsunori ^b   Fujiwara, Michihiro ^b   Ikenoue, Tsuyomu ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

Author keywords

Edaravone; Hypoxia ischemia; Learning impairment; Levine's model; Neonatal rat

Indexed keywords

NORPHENAZONE; SCAVENGER;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; EVALUATION; HISTOPATHOLOGY; JAPAN; LEARNING DISORDER; LONG TERM EXPOSURE; MEMORY DISORDER; NEUROPROTECTION; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION TIME; SHORT COURSE THERAPY; TREATMENT OUTCOME;

ANIMALS; ANIMALS, NEWBORN; ANTIPYRINE; BEHAVIOR, ANIMAL; BRAIN; BRAIN ISCHEMIA; DRUG ADMINISTRATION SCHEDULE; FREE RADICAL SCAVENGERS; HYPOXIA-ISCHEMIA, BRAIN; MAZE LEARNING; MODELS, STATISTICAL; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, WISTAR; TIME FACTORS;

EID: 27644520933     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000185653.49740.c6     Document Type: Article

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