Acidosis in muscle tissue distal to vascular contusion despite unchanged global blood flow in rats: An uncoupling of microvascular blood flow and metabolism?

Microvascular Research

Volumn 70, Issue 1-2, 2005, Pages 111-115

  Karlander, L E ^a   Henriksson, J ^b   Sjoberg F ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Blood flow; Blunt trauma; Ethanol clearance; Lactate; Microdialysis

Indexed keywords

ALCOHOL; LACTIC ACID;

ANAEROBIC CAPACITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLUNT TRAUMA; CONTROLLED STUDY; CONTUSION; DISEASE SEVERITY; FEMORAL ARTERY FLOW; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; MALE; MEDICAL ASSESSMENT; MICRODIALYSIS; MICROVASCULARIZATION; MUSCLE BLOOD FLOW; MUSCLE INJURY; MUSCLE ISCHEMIA; MUSCLE TISSUE; NONHUMAN; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; RAT; TISSUE OXYGENATION; VASCULAR PATENCY;

ACIDOSIS; ANIMALS; BLOOD VESSELS; CONTUSIONS; ETHANOL; FEMORAL ARTERY; HINDLIMB; INJURY SEVERITY SCORE; LACTIC ACID; MALE; MICROCIRCULATION; MICRODIALYSIS; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; TIME FACTORS;

ANIMALIA;

EID: 27644509154     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2005.06.003     Document Type: Article

References (22)

1. E. Bernt, and I. Gutmann Determination with alcohol dehydrogenase and NAD H.U. Bergmeyer Methods of Enzymatic Analysis 3 1974 Verlag Chemie Weinheim 1499 1505
2. G. Burnstock Integration of factors controlling vascular tone Anesthesiology 79 1993 1368 1380
3. L.E. Chen, A.V. Seaber, R.R. Glisson, E.M. Mikat, and J.R. Urbaniak Morphologic and morphometric analyses of rat femoral arteries after crush injury Microsurgery 12 1991 402 411
4. B.C. Cooley, and F.C. Hansen Microvascular repair following local crush and avulsion injury Microsurgery 6 1985 46 48
5. T.A. Creagh, P.J. Broe, P.A. Grace, and D.J. Bouchier-Hayes Blunt trauma-induced upper extremity vascular injuries J. R. Coll. Surg. Edinb. 36 1991 158 160
6. MP. Fink Bench-to-bedside review: cytopathic hypoxia Crit. Care 6 2002 491 499
7. U. Gustafsson, L. Torssell, F. Sjoberg, and A. Sollevi Effect of systemic adenosine infusion on capillary flow and oxygen pressure distributions in skeletal muscle of the rabbit Int. J. Microcirc. Clin. Exp. 13 1993 1 12
8. R.C. Hickner, U. Eklund, S. Mellander, U. Ungerstedt, and J. Henriksson Muscle blood flow in cats: comparison of microdialysis ethanol technique with direct measurement J. Appl. Physiol. 79 1995 638 647
9. R.S. Idler, and l.B. Steichen Complications of replantation surgery Hand Clin. 8 1992 427 451
10. L.E. Karlander, D. Lidman, and L. Franzén The effect of severe contusion on the vessels of the femoral region Scand. J. Plast. Reconstr. Surg. Hand Surg. 25 1991 1 4
11. L.E. Karlander, D. Lidman, and L. Franzen Microvascular surgery after severe contusion injury of the femoral artery in rats Scand. J. Plast. Reconstr. Surg. Hand Surg. 28 1994 19 23
12. L.E. Karlander, U. Gustafsson, D. Lidman, and F. Sjöberg Severe contusion of the femoral vessels in rats alters tissue oxygenation and microvascular blood flow regulation in the skeletal muscles of the limb J. Trauma 48 2000 286 291
13. D.H. Lewis, J. Sandegård, T. Seeman, and E. Zachrisson Angiography of the dilator response in extremity trauma Acta Radiol.: Diagn. 16 1975 679 688
14. O.H. Lowry, and J.V. Passonneau A collection of metabolite assays A Flexible System of Enzymatic Analysis 1972 Academic Press New York 194 201
15. G.M. Mitchell, W.A. Morrison, A. Papadooulos, and B.M. O'Brien A study of the extent and pathology of experimental avulsion injury in rabbit arteries and veins Br. J. Plast. Surg. 38 1985 278 287
16. H. Rosdahl, U. Ungerstedt, L. Jorfeldt, and J. Henriksson Interstitial glucose and lactate balance in human skeletal muscle and adipose tissue studied by microdialysis J. Physiol. 471 1993 637 657
17. B. Rybeck, D.H. Lewis, J. Sandegård, and T. Seeman Early changes in capillary flow and transport following missile wounds Microvasc. Res. 10 1975 267 275
18. B. Rybeck, D.H. Lewis, J. Sandegård, and T. Seeman The immediate hemodynamic and biochemical response to high velocity missiles J. Trauma 15 1975 328 335
19. I.T. Sturm, K.C. Bodily, D.A. Rothenberger, and I.F. Perry Arterial injuries of the extremities following blunt trauma J. Trauma 20 1980 933 936
20. M. van Wijngaarden, L. Omen, A. Rodriguez, and T.R. Smith Management of blunt vascular trauma to the extremities Surg. Gynecol. Obstet. 177 1993 41 48
21. M.A. Vincent, S. Rattigan, and M.G. Clark Microsphere infusion reverses vasoconstrictor-mediated change in hindlimb oxygen uptake and energy status Acta Physiol. Scand. 164 1998 61 69
22. M.S. Wolin, S.A. Gupta, and R.A. Oeckler Superoxide in the vascular system J. Vasc. Res. 39 2002 191 207