Sporadic case of warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis syndrome

Journal of Allergy and Clinical Immunology

Volumn 116, Issue 5, 2005, Pages 1101-1105

  Tarzi, Michael D ^a   Jenner, Michael ^a   Hattotuwa, Keith ^b   Faruqi, Asma Z ^c   Diaz, George A ^d   Longhurst, Hilary J ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b BROOMFIELD HOSPITAL   (United Kingdom)

^c ROYAL LONDON HOSPITAL   (United Kingdom)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Combined immunodeficiency; CXCR4; Myelokathexis; Warts; WHIM syndrome

Indexed keywords

ACICLOVIR; CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN;

ADULT; ARTICLE; BONE MARROW CELL; BONE MARROW DISEASE; CASE REPORT; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; FEMALE; GENE MUTATION; GYNECOLOGIC DISEASE; HERPES SIMPLEX; HERPES ZOSTER; HUMAN; HYPOGAMMAGLOBULINEMIA; IMMUNE DEFICIENCY; INFECTION SENSITIVITY; LABORATORY TEST; MEDICAL EXAMINATION; NEUTROPENIA; PRIORITY JOURNAL; STREPTOCOCCUS INFECTION; VERRUCA VULGARIS; WART VIRUS; WARTS HYPOGAMMAGLOBULINEMIA IMMUNODEFICIENCY AND MYELOKATHEXIS SYNDROME;

AGAMMAGLOBULINEMIA; BONE MARROW; CONDYLOMATA ACUMINATA; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFECTION; MIDDLE AGED; NEUTROPENIA; RECURRENCE; SYNDROME; VULVA;

EID: 27644506418     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2005.08.040     Document Type: Article

References (22)

1. V. Lougaris, R. Bodolato, S. Ferrari, and A. Plebani Hyper immunoglobulin M syndrome due to CD40 deficiency: clinical, molecular and immunological features Immunol Rev 203 2005 48 66
2. M.E. Conley, L.D. Notarangelo, and A. Etzioni Diagnostic criteria for primary immunodeficiencies Clin Immunol 93 1999 190 197
3. A.R. Gennery, A.J. Cant, and P.A. Jeggo Immunodeficiency associated with DNA repair defects Clin Exp Immunol 121 2000 1 7
4. P.A. Hernandez, R.J. Gorlin, J.N. Lukens, S. Taniuchi, J. Bohinject, and F. Francois Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease Nat Genet 34 2003 70 74
5. G.A. Diaz CXCR4 mutations in WHIM syndrome: a misguided immune system? Immunol Rev 203 2005 235 243
6. R.J. Gorlin, B. Gelb, G.A. Diaz, K.G. Lofsness, M.R. Pittelkow, and J.R. Fenyk Jr. WHIM syndrome, an autosomal dominant disorder: clinical, haematological and molecular studies Am J Med Genet 91 2000 368 376
7. W.W. Zuelzer "Myelokathexis" - a new form of chronic granulocytopenia: report of a case N Engl J Med 270 1964 699 704
8. C.E. Krill Jr., H.D. Smith, and A.M. Mauer Chronic idiopathic granulocytopenia N Engl J Med 270 1964 973 979
9. M. Wetzler, M. Talpaz, M.J. Kellagher, J.U. Gutterman, and R. Kurzrook Myelokathexis: normalisation of neutrophil counts and morphology by GM-CSF JAMA 267 1992 2179 2180
10. B. Weston, R.A. Axtell, R.F. Todd, M. Vincent, V.J. Balazovich, and S.J. Suchard Clinical and biologic effects of granulocyte colony stimulating factor in the treatment of myelokathexis J Pediatr 118 1991 229 234
11. D.W.G. Beynon, A. Lopes, B. Daras, and J.M. Monaghan Radical vulvectomy and groin node dissection in a patient with chronic neutropenia - maintenance of leucocyte count using granulocyte colony-stimulating factor Int J Gynecol Cancer 3 1993 405 407
12. M. Wetzler, M. Talpaz, E.S. Kleimerman, A. King, Y.O. Huh, and J.U. Gutterman A new familial immunodeficiency disorder characterised by severe neutropenia, a defective bone marrow release mechanism, and hypogammaglobulinemia Am J Med 89 1990 663 672
13. A.V. Gulino WHIM syndrome: a genetic disorder of leukocyte trafficking Curr Opin Allergy Clin Immunol 3 2003 443 450
14. K. Balabanian, B. Lagane, J.L. Pablos, L. Laurent, T. Planchenault, and O. Verola WHIM syndromes with different genetic abnormalities are accounted for by impaired CXCR4 desensitisation to CXCL12 Blood 105 2005 2249 2257
15. Y.R. Zou, A.H. Kottmann, M. Kuroda, I. Taniuchi, and D.R. Littman Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development Nature 393 1998 595 599
16. K. Tachibana, S. Hirota, H. Iizasa, H. Yoshida, K. Kawabata, and Y. Kataoka The chemokine receptor CXCR4 is essential for vascularisation of the gastrointestinal tract Nature 393 1998 591 594
17. K.M. Ansel, and J.G. Cyster Chemokines in lymphopoiesis and lymphoid organ development Curr Opin Immunol 13 2001 172 179
18. A.V. Gulino, D. Moratto, S. Sozzani, P. Cavadini, K. Otero, and L. Tassone Altered leukocyte response to CXCL12 in patients with warts, hypogammaglobulinemia, infections, myelokathexis syndrome (WHIM) syndrome Blood 104 2004 444 452
19. N. Signoret, M.M. Rosenkilde, P.J. Klasse, T.W. Schwartz, M.H. Malim, J.A. Hoxie, and M. Marsh Differential regulation of CXCR4 and CCR5 endocytosis J Cell Sci 111 1998 2819 2830
20. B. Haribabu, R.M. Richardson, I. Fisher, S. Sozzani, S.C. Peiper, and R. Horuk Regulation of human chemokine receptors CXCR4: role of phosphorylation in desensitisation and internalisation J Biol Chem 272 1997 28726 28731
21. S. Imashuku, A. Miyagawa, T. Chiyonobu, H. Ishida, T. Yoshihara, and T. Teramura Epstein-Barr virus-associated T-lymphoproliferative disease with hematophagic syndrome, followed by fatal intestinal B lymphoma in a young adult female with WHIM syndrome Ann Hematol 81 2002 470 473
22. K.M. Chae, J.O. Ertle, and M.D. Tharp B-cell lymphoma in a patient with WHIM syndrome J Am Acad Dermatol 44 2001 124 128