Late-gestation rat myometrial cells express multiple isoforms of phospholipase A2 that mediate PCB 50-induced release of arachidonic acid with coincident prostaglandin production

Toxicological Sciences

Volumn 88, Issue 1, 2005, Pages 222-230

  Brant, Kelly ^a   Loch Caruso, Rita ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Arachidonic acid; Myometrium; PCBs; Phospholipase A2; Prostaglandins

Indexed keywords

2,2',4,6 TETRACHLOROBIPHENYL; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ARACHIDONIC ACID; CALCIUM CHANNEL L TYPE; EGTAZIC ACID; MITOGEN ACTIVATED PROTEIN KINASE P38; NIFEDIPINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN; VOLTAGE GATED CALCIUM CHANNEL;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL LABELING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; EXTRACELLULAR CALCIUM; GESTATIONAL AGE; IMMUNOBLOTTING; MOUSE; MYOMETRIUM; NONHUMAN; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; UTERUS FUNCTION;

ANIMALS; ARACHIDONIC ACID; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; ENVIRONMENTAL POLLUTANTS; ENZYME INHIBITORS; FEMALE; FETUS; IMIDAZOLES; MYOMETRIUM; NIFEDIPINE; PHOSPHOLIPASES A; POLYCHLORINATED BIPHENYLS; PREGNANCY; PROSTAGLANDINS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; SPECIFIC PATHOGEN-FREE ORGANISMS;

ANIMALIA;

EID: 27644497229     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfi296     Document Type: Article

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