Apo2L/TRAIL is an indirect mediator of apoptosis induced by interferon-α in human myeloma cells

FEBS Letters

Volumn 579, Issue 27, 2005, Pages 6217-6222

  Gómez Benito, Maria ^a   Balsas, Patricia ^a   Bosque, Alberto ^a   Anel, Alberto ^a   Marzo, Isabel ^a   Naval, Javier ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Apo2L TRAIL; Apoptosis; Caspases; Interferon ; Multiple myeloma

Indexed keywords

BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; CASPASE 8 INHIBITOR; RECOMBINANT ALPHA INTERFERON; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG SENSITIVITY; HUMAN; HUMAN CELL; MONOCYTE; MYELOMA CELL; PRIORITY JOURNAL; PROTEIN SECRETION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CASPASE 8; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CYSTEINE PROTEINASE INHIBITORS; HUMANS; INTERFERON-ALPHA; MEMBRANE GLYCOPROTEINS; MONOCYTES; MULTIPLE MYELOMA; OLIGOPEPTIDES; PROTEIN TRANSPORT; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 27544479080     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.10.007     Document Type: Article

References (19)

1. S. Ahmed, and K.R. Rai Interferon in the treatment of hairy-cell leukemia Best Pract. Res. Clin. Haematol. 16 2003 69 81
2. M. Baccarani A randomized study of interferon-alpha versus interferon-alpha and low-dose arabinosyl cytosine in chronic myeloid leukemia Blood 99 2002 1527 1535
3. R.A. Kyle, and S.V. Rajkumar Multiple myeloma N. Engl. J. Med. 351 2004 1860 1873
4. J. Bladé, and J. Esteve Viewpoint on the impact of interferon in the treatment of multiple myeloma: benefit for a small proportion of patients? Med. Oncol. 17 2000 77 84
5. Q. Chen, B. Gong, A.S. Mahmoud-Ahmed, A. Zhou, E.D. Hsi, M. Hussein, and A. Almasan Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma Blood 98 2001 2183 2192
6. T. Otsuki, O. Yamada, H. Sakaguchi, A. Tomokuni, H. Wada, Y. Yawata, and A. Ueki Human myeloma cell apoptosis induced by interferon-alpha Br. J. Haematol. 103 1998 518 529
7. C. Crowder, O. Dahle, R.E. Davis, O.S. Gabrielsen, and S. Rudikoff PML mediates IFN-alpha-induced apoptosis in myeloma by regulating TRAIL induction Blood 105 2005 1280 1287
8. D. Lawrence Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions Nat. Med. 7 2001 383 385
9. M.J. Martinez-Lorenzo, M.A. Alava, S. Gamen, K.J. Kim, A. Chuntharapai, A. Pineiro, J. Naval, and A. Anel Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells Eur. J. Immunol. 28 1998 2714 2725
10. P. Perez-Galan, I. Marzo, P. Giraldo, D. Rubio-Felix, P. Lasierra, L. Larrad, A. Anel, and J. Naval Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia Leukemia 16 2002 2106 2114
11. S. Gamen, A. Anel, P. Lasierra, M.A. Alava, M.J. Martinez-Lorenzo, A. Piñeiro, and J. Naval Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way FEBS Lett. 417 1997 360 364
12. L. Thyrell, S. Erickson, B. Zhivotovsky, K. Pokrovskaja, O. Sangfelt, J. Castro, S. Einhorn, and D. Grander Mechanisms of interferon-alpha induced apoptosis in malignant cells Oncogene 21 2002 1251 1262
13. T. Panaretakis, K. Pokrovskaja, M.C. Shoshan, and D. Grander Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax Oncogene 22 2003 4543 4556
14. G. Dorothee, I. Vergnon, J. Menez, H. Echchakir, D. Grunenwald, M. Kubin, S. Chouaib, and F. Mami-Chouaib Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity J. Immunol. 169 2002 809 817
15. S. Ehrlich, C. Infante-Duarte, B. Seeger, and F. Zipp Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes Cytokine 24 2003 244 253
16. N. Kayagaki, N. Yamaguchi, M. Nakayama, H. Eto, K. Okumura, and H. Yagita Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs J. Exp. Med. 189 1999 1451 1460
17. T.J. Kemp, B.D. Elzey, and T.S. Griffith Plasmacytoid dendritic cellderived IFN-alpha induces TNF-related apoptosis-inducing ligand/Apo-2L-mediated antitumor activity by human monocytes following CpG oligodeoxynucleotide stimulation J. Immunol. 171 2003 212 218
18. C. Tecchio IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells Blood 103 2004 3837 3844
19. T. Yamamoto Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to antitumor effects of interferon-alpha/5-fluorouracil against Hepatocellular Carcinoma Clin. Cancer Res. 10 2004 7884 7895