Effects of botulinum toxin B on refractory detrusor overactivity: A randomized, double-blind, placebo controlled, crossover trial

Journal of Urology

Volumn 174, Issue 5, 2005, Pages 1873-1877

  Ghei, M ^a   Maraj, B H ^a   Miller, R ^a   Nathan, S ^a   O'Sullivan, C ^a   Fowler, C J ^a   Shah, P J R ^a   Malone Lee, J ^a  

^a WHITTINGTON HOSPITAL   (United Kingdom)

Author keywords

Botulinum toxin type B; Cross over studies; Urinary incontinence

Indexed keywords

BOTULINUM TOXIN B; MUSCARINIC RECEPTOR BLOCKING AGENT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DETRUSOR MUSCLE; DILUTION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; INCONTINENCE; MALAISE; MALE; OVERACTIVE BLADDER; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME; URINARY FREQUENCY; URINE RETENTION; URINE VOLUME; WILCOXON SIGNED RANKS TEST; XEROSTOMIA;

EID: 27544477692     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000177477.83991.88     Document Type: Article

References (20)

1. Setler, P.: The biochemistry of botulinum toxin type B. Neurology, suppl., 55: S22, 2000
2. Hallett, M.: One man's poison-clinical applications of botulinum toxin. N Engl J Med, 341: 118, 1999
3. Scott, A. B.: Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery. Ophthalmology, 87: 1044, 1980
4. Bentsianov, B., Zalvan, C. and Blitzer, A.: Noncosmetic uses of botulinum toxin. Clin Dermatol, 22: 82, 2004
5. Setler, P. E.: Therapeutic use of botulinum toxins: background and history. Clin J Pain, suppl., 18: S119, 2002
6. Dykstra, D. D. and Sidi, A. A.: Treatment of detrusor-sphincter dyssynergia with botulinum A toxin: a double-blind study. Arch Phys Med Rehabil, 71: 24, 1990
7. Schurch, B., Hauri, D., Rodic, B., Curt, A., Meyer, M. and Rossier, A. B.: Botulinum-A toxin as a treatment of detrusorsphincter dyssynergia: a prospective study in 24 spinal cord injury patients. J Urol, 155: 1023, 1996
8. Schurch, B., Stöhrer, M., Kramer, G., Schmid, D. M., Gaul, G. and Hauri, D.: Botulinum-A toxin for treating detrusor hyperreflexia in spinal cord injured patients: a new alternative to anticholinergic drugs? Preliminary results. J Urol, 164: 692, 2000
9. Reitz, A., Stohrer, M., Kramer, G., Del Popolo, G., Chartier-Kastler, E., Pannek, J. et al: European experience of 200 cases treated with botulinum-A toxin injections into the detrusor muscle for urinary incontinence due to neurogenic detrusor overactivity. Eur Urol, 45: 510, 2004
10. Schurch, B., de Seze, M., Denys, P., Chartier-Kastler, E., Ismael, S. and Haab, F.: Botulinum Toxin A (BOTOX) in neurogenic urinary incontinence: results from a multi-centre, randomised controlled trial. Neurourol Urodyn, 23: 609, 2004
11. Brin, M. F., Lew, M. F., Adler, C. H., Comella, C. L., Factor, S. A., Jankovic, J. et al: Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia. Neurology, 53: 1431, 1999
12. Reitz, A. and Schurch, B.: Botulinum toxin type B injection for management of type A resistant neurogenic detrusor overactivity. J Urol, 171: 804, 2004
13. Dykstra, D. D., Pryor, J. and Goldish, G.: Use of botulinum toxin type B for the treatment of detrusor hyperreflexia in a patient with multiple sclerosis: a case report. Arch Phys Med Rehabil, 84: 1399, 2003
14. Dykstra, D., Enriquez, A. and Valley, M.: Treatment of overactive bladder with botulinum toxin type B: a pilot study. Int Urogynecol J Pelvic Floor Dysfunct, 14: 424, 2003
15. Miller, R. A.: Ten years of sedoanalgesia and how it has affected urological practice. Arch Ital Urol Androl, 69: 29, 1997
16. Deaney, C., Glickman, S., Gluck, T. and Malone-Lee, J. G.: Intravesical atropine suppression of detrusor hyperreflexia in multiple sclerosis. J Neurol Neurosurg Psychiatry, 65: 957, 1998
17. Gray, R., Wagg, A. and Malone-Lee, J. G.: Differences in detrusor contractile function in women with neuropathic and idiopathic detrusor instability. Br J Urol, 80: 222, 1997
18. Dressier, D. and Benecke, R.: Autonomic side effects of botulinum toxin type B treatment of cervical dystonia and hyperhidrosis. Eur Neurol, 49: 34, 2003
19. Wyndaele, J. J. and Van Dromme, S. A.: Muscular weakness as side effect of botulinum toxin injection for neurogenic detrusor overactivity. Spinal Cord, 40: 599, 2002
20. Jankovic, J., Vuong, K. D. and Ahsan, J.: Comparison of efficacy and immunogenicity of original versus current botulinum toxin in cervical dystonia. Neurology, 60: 1186, 2003