Efficiency of adeno-associated virus type-2 vectors in non-human primate Schwann cells

NeuroReport

Volumn 16, Issue 16, 2005, Pages 1757-1762

  Girard, Christelle ^a   Tenenbaum, Liliane ^c   Chtarto, Abdel ^c   Attali, Bernard ^d   Salvetti, Anna ^b   Bachelin, Corinne ^a   Baron Van Evercooren, Anne ^a   Lachapelle, Francois ^a,e  

^a INSERM   (France)

^b HÔTEL DIEU   (France)

^c ERASME HOSPITAL   (Belgium)

^d TEL AVIV UNIVERSITY   (Israel)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Adeno associated virus type 2 vector; Central nervous system; Etoposide; Ex vivo condition; Hydroxyurea; Primate Schwann cell

Indexed keywords

ADENOVIRUS VECTOR; BETA ACTIN; ETOPOSIDE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; HYDROXYUREA; MYELIN BASIC PROTEIN; TETRACYCLINE;

ADENOVIRUS 2; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; CYTOMEGALOVIRUS; DEMYELINATION; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; MACACA; MOUSE; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; SCHWANN CELL; SPINAL CORD LESION; VIRAL GENE DELIVERY SYSTEM; VIRUS INFECTION;

ANALYSIS OF VARIANCE; ANIMALS; CELL COUNT; CELL PROLIFERATION; CELL TRANSPLANTATION; CELLS, CULTURED; CYTOMEGALOVIRUS; DEMYELINATING DISEASES; DEPENDOVIRUS; ETOPOSIDE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HYDROXYUREA; IMMUNOHISTOCHEMISTRY; MACACA FASCICULARIS; MICE; MYELIN BASIC PROTEINS; NUCLEIC ACID SYNTHESIS INHIBITORS; PROMOTER REGIONS (GENETICS); SCHWANN CELLS; TIME FACTORS; TRANSDUCTION, GENETIC;

EID: 27544458099     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000185960.11465.16     Document Type: Article

References (25)

1. Rutkowski JL, Kirk CJ, Lerner MA, Tennekoon GI. Purification and expansion of human Schwann cells in vitro. Nat Med 1995; 1:80-83.
2. Bachelin C, Lachapelle F, Girard C, Moissonnier P, Serguera-Lagache C, Mallet J, et al. Efficient myelin repair in the macaque spinal cord by autologous grafts of Schwann cells. Brain 2005; 128:540-549.
3. Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, et al. Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet 1994; 8: 148-154.
4. Lehtonen E, Bonnaud F, Melas C, Lubansu A, Malgrange B, Chtarto A, et al. AAV2 vectors mediate efficient and sustained transduction of rat embryonic ventral mesencephalon. Neuroreport 2002; 13:1503-1507.
5. Russell DW, Alexander IE, Miller AD. DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors. Proc Natl Acad Sci USA 1995; 92:5719-5723.
6. Avellana-Adalid V, Bachelin C, Lachapelle F, Escriou C, Ratzkin B, Baron-Van Evercooren A. In vitro and in vivo behaviour of NDF-expanded monkey Schwann cells. Eur J Neurosci 1998; 10:291-300.
7. Chtarto A, Bender HU, Hanemann CO, Kemp T, Lehtonen E, Levivier M, et al. Tetracycline-inducible transgene expression mediated by a single AAV vector. Gene Ther 2003; 10:84-94.
8. Tennenbaum L, Hamdane M, Pouzet M, Avalosse B, Stathopoulos A, Jurysta F, et al. Cellular contaminants of adeno-associated virus vector stocks can enhance transduction. Gene Ther 1999; 6:1045-1053.
9. Xu L, Daly T, Gao C, Flotte TR, Song S, Byrne BJ, et al. CMV-beta-actin promoter directs higher expression from an adeno-associated viral vector in the liver than the cytomegalovirus or elongation factor 1 alpha promoter and results in therapeutic levels of human factor X in mice. Hum Gene Ther 2001; 12:563-573.
10. Salvetti A, Oreve S, Chadeuf G, Favre D, Cherel Y, Champion-Arnaud P, et al. Factors influencing recombinant adeno-associated virus production. Hum Gene Ther 1998; 9:695-706.
11. Zolotukhin S, Byrne BJ, Mason E, Zolotukhin I, Potter M, Chesnut K, et al. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Ther 1999; 6:973-985.
12. Ranscht B, Clapshaw PA, Price J, Noble M, Seifert W. Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside. Proc Natl Acad Sci USA 1982; 79:2709-2713.
13. Girard C, Bemelmans A, Dufour N, Mallet J, Bachelin C, Nait-Oumesmar B, et al. Grafts of brain derived neurotrophic factor and neurotrophin 3-transduced Schwann cells lead to functional recovery of the demyelinated mouse spinal cord. J Neurosci 2005; 25:7507-7516.
14. Glatzel M, Flechsig E, Navarro B, Klein MA, Paterna JC, Bueler H, et al. Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system. Proc Natl Acad Sci USA 2000; 97:442-447.
15. Fleming J, Ginn SL, Weinberger RP, Trahair TN, Smythe JA, Alexander IE. Adeno-associated virus and lentivirus vectors mediate efficient and sustained transduction of cultured mouse and human dorsal root ganglia sensory neurons. Hum Gene Ther 2001; 12:77-86.
16. Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 1998; 72:1438-1445.
17. Zhong L, Li W, Yang Z, Qing K, Tan M, Hansen J, et al. Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells. Hum Gene Ther 2004; 15:1207-1218.
18. Alexander IE, Russell DW, Miller AD. DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors. J Virol 1994; 68:8282-8287.
19. Bantel-Schaal U. Chromosomal integration of adeno-associated parvovirus DNA limits proliferation and dispersal of human MKr melanoma cells in co-cultures with human fibroblasts. Cancer Lett 1999; 147:45-53.
20. Matsui WH, Gladstone DE, Vala MS, Barber JP, Brodsky RA, Smith BD, Jones RJ. The role of growth factors in the activity of pharmacological differentiation agents. Cell Growth Differ 2002; 13:275-283.
21. Hillgenberg M, Schlehofer JR, von Knebel Doeberitz M, Klein-Bauernschmitt P. Enhanced sensitivity of small cell lung cancer cell lines to cisplatin and etoposide after infection with adeno-associated virus type 2. Eur J Cancer 1999; 35:106-110.
22. Forghani R, Garofalo L, Foran DR, Farhadi HF, Lepage P, Hudson TJ, et al. A distal upstream enhancer from the myelin basic protein gene regulates expression in myelin-forming schwann cells. J Neurosci 2001; 21:3780-3787.
23. Peltonen K, Kiviharju TM, Jarvinen PM, Ra R, Laiho M. Melanoma cell lines are susceptible to histone deacetylase inhibitor TSA provoked cell cycle arrest and apoptosis. Pigment Cell Res 2005; 18:196-202.
24. Johansen J, Rosenblad C, Andsberg K, Moller A, Lundberg C, Bjorlund A, et al. Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS. Gene Ther 2002; 9:1291-1301.
25. Asano T, Nakamura K, Fujii H, Horichi N, Ohmori T, Hasegawa K, et al. Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation. Br J Cancer 2005; 92:1486-1492.