Syntheses and biological activities of daunorubicin analogs with uncommon sugars

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 23, 2005, Pages 6381-6387

  Zhu, Lizhi ^a   Cao, Xianhua ^a   Chen, Wenlan ^a   Zhang, Guisheng ^a   Sun, Duxin ^a   Wang, Peng George ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Anticancer; Daunorubicin; Glycosylation; Structure activity relationship (SAR)

Indexed keywords

7 (4 AZIDO 2,3,4,5,5,6 TETRADEOXY ALPHA LEVO ERYTHRO HEXOPYRANOSYL) DAUNORUBICINONE; 7 (ALPHA AMICETOSYL)DAUNORUBICINONE; 7 (ALPHA CLADINOSYL)DAUNORUBICINONE; 7 (ALPHA MYCAROSYL)DAUNORUBICINONE; 7 (ALPHA OLEAUDROSYL)DAUNORUBICINONE; 7 (ALPHA RHAMNOSYL)DAUNORUBICINONE; ANTHRACYCLINE; ANTHRACYCLINE ANTIBIOTIC AGENT; CARBOHYDRATE DERIVATIVE; DAUNORUBICIN DERIVATIVE; DNA; SUGAR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DAUNORUBICIN; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE;

EID: 27544456829     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.06.053     Document Type: Article

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