Smooth muscle dynamics and maximal expiratory flow in asthma

Journal of Applied Physiology

Volumn 99, Issue 5, 2005, Pages 1885-1890

  Lambert, Rodney K ^a   Wilson, Theodore A ^b,c  

^a MASSEY UNIVERSITY   (New Zealand)

^b University of Minnesota   (United States)

^c 107 Akerman Hall ^*  (United States)

Author keywords

Constricted lungs; Flow volume curve; Mathematical model; Mechanics

Indexed keywords

AIRWAY CONSTRICTION; ANAFI MODEL; ARTICLE; ASTHMA; COMPUTER MODEL; EXPIRATORY FLOW; LAMBERT MODEL; LUNG FLOW VOLUME CURVE; LUNG MODEL; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MUSCLE CONTRACTION; PRIORITY JOURNAL; RESIDUAL VOLUME; RESPIRATORY AIRFLOW; SENSITIVITY ANALYSIS; SMOOTH MUSCLE; VITAL CAPACITY;

ASTHMA; BRONCHOCONSTRICTION; EXHALATION; HUMANS; LUNG; MODELS, BIOLOGICAL; MUSCLE, SMOOTH; PRESSURE; RESIDUAL VOLUME;

EID: 27544440883     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00450.2005     Document Type: Article

References (20)

1. Anafi RC and Wilson TA. Empirical model for dynamic force-length behavior of airway smooth muscle. J Appl Physiol 92: 455-460, 2002.
2. Anafi RC, Beck KC, and Wilson TA. Impedance, gas mixing, and bimodal ventilation in constricted lungs. J Appl Physiol 94: 1003-1011, 2003.
3. Gunst SJ. Contractile force of canine airway smooth muscle during cyclical length changes. J Appl Physiol 55: 759-769, 1983.
4. Gunst SJ and Stropp JQ. Pressure-volume and length-stress relationships in canine bronchi in vitro. J Appl Physiol 64: 2522-2531, 1988.
5. Gunst SJ, Warner DO, Wilson TA, and Hyatt RE. Parenchymal interdependence and airway response to methacholine in excised dog lobes. J Appl Physiol 65: 2490-2497, 1988.
6. James AL, Hogg JC, Dunn LA, and Pare PD. The use of the internal perimeter to compare airway size and to calculate smooth muscle shortening. Am Rev Respir Dis 138: 136-139, 1988.
7. Lai-Fook SJ. A continuum mechanics analysis of pulmonary vascular interdependence in isolated dog lobes. J Appl Physiol 46: 419-429, 1979.
8. Lambert RK. Sensitivity and specificity of the computational model for maximal expiratory flow. J Appl Physiol 57: 958-970, 1984.
9. Lambert RK. Bronchial mechanical properties and maximal expiratory flows. J Appl Physiol 62: 2426-2435, 1897.
10. Lambert RK and Beck KC. Airway area distribution from the forced expiration maneuver. J Appl Physiol 97: 570-578, 2004.
11. Lambert RK, Wilson TA, Hyatt RE, and Rodarte JR. A computational model for expiratory flow. J Appl Physiol 52: 44-56, 1982.
12. McNamara JJ, Castile RG, Ludwig MS, Glass GM, Ingram RH Jr, and Fredberg JJ. Heterogeneous regional behavior during forced expiration before and after histamine inhalation in dogs. J Appl Physiol 76: 356-369, 1994.
13. Mehta D, Wu MF, and Gunst SJ. Role of contractile protein activation in the length-dependent modulation of tracheal smooth muscle force. Am J Physiol Cell Physiol 270: C243-C252, 1996.
14. Mele MFV, Harris RS, Layfield JDH, and Venegas JG. Topographic basis of bimodal ventilation-perfusion distributions during bronchoconstriction in sheep. Am J Respir Crit Care Med 171: 714-721, 2005.
15. Moore BJ, Hilliam CC, Verburgt LM, Wiggs BR, Vedal S, and Pare PD. Shape and position of the complete dose-response curve for inhaled methacholine in normal subjects. Am J Respir Crit Care Med 154: 642-648, 1996.
16. Pellegrino R, Violante B, and Brusasco V. Maximal bronchoconstriction in humans. Relationship to deep inhalation and airway sensitivity. Am J Respir Crit Care Med 153: 115-121, 1996.
17. Pellegrino R, Violante B, Selleri R, and Brusasco V. Changes in residual volume during induced bronchoconstriction in healthy and asthmatic subjects. Am J Respir Crit Care Med 150: 363-368, 1994.
18. Pellegrino R, Wilson O, Jenouri G, and Rodarte JR. Lung mechanics during induced bronchoconstriction. J Appl Physiol 81: 964-975, 1996.
19. Reynolds DB. Steady expiratory flow-pressure relationship in a model of the human bronchial tree. J Biomech Eng 104: 153-158, 1982.
20. Shen X, Wu MF, Tepper RS, and Gunst SJ. Mechanisms for the mechanical response of airway smooth muscle to length oscillations. J Appl Physiol 83: 731-738, 1997.