Estimation of cancer drug potencies and relative potencies from in vitro data

Journal of Biopharmaceutical Statistics

Volumn 15, Issue 6, 2005, Pages 903-912

  Le, Chap T ^a,c   Grambsch, Patricia M ^a   Liu, An ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MEDTRONIC INC   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Drug potency; Efficiency; Maximum likelihood estimation; Mean square error; Measurement error model; Relative potency

Indexed keywords

CANCER GROWTH; CANCER RESEARCH; CELL COUNT; DOSE RESPONSE; DRUG POTENCY; MAXIMUM LIKELIHOOD METHOD; PRIORITY JOURNAL; REVIEW; SIMULATION; STATISTICAL MODEL;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIKELIHOOD FUNCTIONS; MODELS, STATISTICAL; THERAPEUTIC EQUIVALENCY;

EID: 27544438603     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543400500265595     Document Type: Review

References (10)

1. Armtage, P. (1977). Statistical Methods in Medical Research. New York: John Wiley and Sons.
2. Ashton, W. D. (1972). The Logit Transformation. New York: Hafner Publishing Co.
3. 50. J. Am. Stat. Assoc. 74:344-354.
4. Hubert, J. J. (1984). Bioassay. Dubuque, Iowa: Kendall/Hunt Publishing Co.
5. Johnson, N. L., Kotz, S. (1969). Discrete Distributions. Boston: Houghton Mifflin Company.
6. Pflug, I. J., Holcomb, R. G. (1977). Principles of thermal destruction of microorganisms. In: Block, S. S., ed. Disinfaction, Sterilization, and Preservation. Philadelphia: Lea and Febiger, pp. 933-944.
7. 50 in quantal bioassay. Biometrics 43:825-832.
8. Sundararaj, N., Le, C., McHugh, R. (1982). Estimation of the efficacy of thermal microbial disinfection. Biometrics 38:371-376.
9. Tallarida, R. J., Jacob, L. S. (1979). The Dose-Response Relation in Pharmacology. New York: Springer-Verlag.
10. Tallarida, R. J., Murray, R. B. (1981). Manual of Pharmacologic Calculations with Computer Programs. New York: Springer-Verlag.