Novel peptide toxins from acrorhagi, aggressive organs of the sea anemone Actinia equina

Toxicon

Volumn 46, Issue 7, 2005, Pages 768-774

  Honma, Tomohiro ^a   Minagawa, Sonomi ^a   Nagai, Hiroshi ^a   Ishida, Masami ^a   Nagashima, Yuji ^a   Shiomi, Kazuo ^a  

^a TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Acrorhagi; Actinia equina; cDNA cloning; Peptide toxin; Sea anemone

Indexed keywords

ACRORHAGIN I; ACRORHAGIN IA; ACRORHAGIN II; ACRORHAGIN IIA; HAINANTOXIN I; NEUROTOXIN; OMEGA CONOTOXIN MVIIB; PEPTIDE; SEA ANEMONE TOXIN; SEPHADEX; SPIDER VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; GEL FILTRATION; LD 50; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEA ANEMONE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CNIDARIAN VENOMS; DNA, COMPLEMENTARY; MARINE TOXINS; MOLECULAR SEQUENCE DATA; PEPTIDES; SEA ANEMONES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

ACTINIA EQUINA; ACTINIARIA; ARANEAE; CONUS MAGUS; DECAPODA (CRUSTACEA); GASTROPODA; ORNITHOCTONUS HAINANA; PHONEUTRIA NIGRIVENTER;

EID: 27444447279     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2005.08.003     Document Type: Article

References (25)

1. G. Anderluh, Z. Podlesek, and P. Maček A common motif in proparts of Cnidarian toxins and nematocyst collagens and its putative role Biochim. Biophys. Acta 1476 2000 372 376
2. G. Anderluh, and P. Maček Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria) Toxicon 40 2002 111 124
3. O. Castañeda, O. Sotolongo, A.M. Amor, R. Stöcklin, A.J. Anderson, and A.L., Harvey Engström Å., Wernstedt, C., Karlsson, E., 1995. Characterization of a potassium channel toxin from the Caribbean sea anemone Stichodactyla helianthus. Toxicon 33 1995 603 613
4. M.D.N. Cordeiro, S.G. de Figueiredo, A.D.C. Valentim, C.R. Diniz, V.R. von Eickstedt, J. Gilroy, and M. Richardson Purification and amino acid sequences of six Tx3 type neurotoxins from the venom of the Brazilian 'armed' spider Phoneutria nigriventer (keys.) Toxicon 31 1993 35 42
5. J. Cotton, M. Crest, F. Bouet, N. Alessandri, M. Gola, E. Forest, E. Karlsson, O. Castañeda, A.L. Harvey, C. Vita, and A. Ménez A potassium-channel toxin from the sea anemone Bunodosoma granulifera, an inhibitor for Kv1 channels Revision of the amino acid sequence, disulfide-bridge assignment, chemical synthesis, and biological activity. Eur. J. Biochem. 244 1997 192 202
6. S. Diochot, H. Schweitz, L. Béress, and M. Lazdunski Sea anemone peptides with a specific blocking activity against the fast inactivating potassium channel Kv3.4 J. Biol. Chem. 273 1998 6744 6749
7. I. Ferlan, and D. Lebez Equinatoxin, a lethal protein from Actinia equina-I Purification and characterization. Toxicon 12 1974 57 61
8. G.S. Gendeh, L.C. Young, L.C. de Medeiros, K. Jeyaseelan, A.L. Harvey, and M.C.M. Chung A new potassium channel toxin from the sea anemone Heteractis magnifica: isolation, cDNA cloning, and functional expression Biochemistry 36 1997 11461 11471
9. T. Honma, H. Nagai, Y. Nagashima, and K. Shiomi Molecular cloning of an epidermal growth factor-like toxin and two sodium channel toxins from the sea anemone Stichodactyla gigantea Biochim. Biophys. Acta 1652 2003 103 106
10. T. Honma, Y. Hasegawa, M. Ishida, H. Nagai, Y. Nagashima, and K. Shiomi Isolation and molecular cloning of novel peptide toxins from the sea anemone Antheopsis maculata Toxicon 45 2005 33 41
11. Kem, W.R., 1988. Sea anemone toxins: structure and action. In: Hessinger, D.A., Lenhoff, H.M. (Eds.), The Biology of Nematocysts, Academic Press, New York, pp. 375 - 405.
12. D. Li, Y. Xiao, W. Hu, J. Xie, F. Bosmans, J. Tytgat, and S. Liang Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana FEBS Lett. 555 2003 616 622
13. X.-Y. Lin, M. Ishida, Y. Nagashima, and K. Shiomi A polypeptide toxin in the sea anemone Actinia equina homologous with other sea anemone sodium channel toxins: isolation and amino acid sequence Toxicon 34 1996 57 65
14. J.T. Litchfield Jr, and F. Wilcoxon A simplified method of evaluating dose-effect experiments J. Pharmac. Exp. Ther. 96 1949 99 113
15. W.H. Liu, L. Wang, Y.L. Wang, L.S. Peng, W.Y. Wu, W.L. Peng, X.Y. Jiang, H.B. Tu, H.P. Chen, P. Ou-Yang, and A.L. Xu Cloning and characterization of a novel neurotoxin from the sea anemone Anthopleura sp Toxicon 41 2003 793 801
16. O.H. Lowry, A.L. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the folin phenol reagent J. Biol. Chem. 193 1951 265 275
17. S. Minagawa, M. Ishida, Y. Nagashima, and K. Shiomi Primary structure of a potassium channel toxin from the sea anemone Actinia equina FEBS Lett. 427 1998 149 151
18. H. Nagai, N. Oshiro, K. Takuwa-Kuroda, S. Iwanaga, M. Nozaki, and T. Nakajima Novel proteinaceous toxins from the nematocyst venom of the Okinawan sea anemone Phyllodiscus semoni Kwietniewski Biochem. Biophys. Res. Commun. 294 2002 760 763
19. R.S. Norton Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel Toxicon 29 1991 1051 1084
20. B.M. Olivera, W.R. Gray, R. Zeikus, J.M. McIntosh, J. Varga, J. Rivier, V. de Santos, and L.J. Cruz Peptide neurotoxins from fish-hunting cone snails Science 230 1985 1338 1343
21. + channels. J. Biol. Chem. 270 1995 25121 25126
22. K. Shiomi, W.-H. Qian, X.-Y. Lin, K. Shimakura, Y. Nagashima, and M. Ishida Novel polypeptide toxins with crab lethality from the sea anemone Anemonia erythraea Biochim. Biophys. Acta 1335 1997 191 198
23. K. Shiomi, T. Honma, M. Ide, Y. Nagashima, M. Ishida, and M. Chino An epidermal growth factor-like toxin and two sodium channel toxins from the sea anemone Stichodactyla gigantea Toxicon 41 2003 229 236
24. A. Spagnuolo, L. Zanetti, L. Cariello, and R. Piccoli Isolation and characterization of two genes encoding calitoxins, neurotoxic peptides from Calliactis parasitica (Cnidaria) Gene 138 1994 187 191
25. R.B. Williams Acrorhagi, catch tentacles and sweeper tentacles: a synopsis of 'aggression' of actiniarian and scleractinian Cnidaria Hydrobiologia 216/217 1991 539 545