Rapid detection of nucleophosmin (NPM1) mutations in acute myeloid leukemia by denaturing HPLC

Clinical Chemistry

Volumn 51, Issue 11, 2005, Pages 2165-2167

  Ammatuna, Emanuele ^a   Noguera, Nèlida Inès ^a   Zangrilli, Daniela ^a   Curzi, Paola ^a   Panetta, Paola ^a   Bencivenga, Paola ^b   Amadori, Sergio ^a   Federici, Giorgio ^a,b,c   Lo Coco, Francesco ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^c TOR VERGATA UNIVERSITY HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPLASMIN;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BONE MARROW BIOPSY; CHROMOSOME 5Q; CHROMOSOME 7Q; CHROMOSOME DELETION 5; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; GENE; GENE LOCATION; GENE MUTATION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NPM1 GENE; NUCLEOTIDE SEQUENCE; PROGNOSIS; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MUTATION; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 27444446955     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2005.055707     Document Type: Article

References (11)

1. Dumbar TS, Gentry GA, Olson MO. Interaction of nucleolar phosphoprotein B23 with nucleic acids. Biochemistry 1989;28:9495-501.
2. Okuda M, Horn HF, Tarapore P, Tokuyama Y, Smulian AG, Chan PK, et al. Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication. Cell 2000;103:127-40.
3. Colombo E, Marine JC, Danovi D, Falini B, Pelicci PG. Nucleophosmin regulates the stability and transcriptional activity of p53. Nat Cell Biol 2002;4:529-33.
4. Kurki S, Peltonen K, Latonen L, Kiviharju TM, Ojala PM, Meek D, et al. Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation. Cancer Cell 2004;5:465-75.
5. Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, et al. Cytoplasmic nucleophosmin (NPM) identifies a subtype of acute myelogenous leukemia with a normal karyotype and NPM1 gene mutations. N Engl J Med 2005;352:254-66.
6. Bennett JM, Catovsky D, Daniel MT, Randrin G, Galton DA, Gralnick HR, et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) Co-operative Group. Br J Haematol 1976;33:451-8.
7. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, et al. Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-MO). Br J Haematol 1991;78:325-9.
8. Chomczynsky P, Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate-phenol chloroform extraction. Anal Biochem 1987;162:156-9.
9. van Dongen JJ, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G, et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia. Leukemia 1999;13:1901-28.
10. Werner-Favre C, Engel E, Beris P. Translocation t(3;5) in ANLL. Cancer Genet Cytogenet 1985;16:279.
11. Bullrich F, Morris SW, Hummel M, Pileri S, Stein H, Croce CM. Nucleophosmin (NPM) gene rearrangements in Ki-1-positive lymphomas. Cancer Res 1994;54:2873-7.