Ataxia, peripheral neuropathy, and anti-gliadin antibody. Guilt by association?

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 76, Issue 11, 2005, Pages 1601-1603

  Lock, R J ^a   Pengiran Tengah, D S N A ^b   Unsworth, D J ^a   Ward, J J ^a   Wills, A J ^b  

^a SOUTHMEAD HOSPITAL   (United Kingdom)

^b QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLIADIN ANTIBODY; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; IMMUNOGLOBULIN A ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE ANTIBODY;

ADULT; AGED; ANTIBODY DETECTION; ANTIGEN EXPRESSION; ARTICLE; ATAXIA; CELIAC DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HEREDITARY ATAXIA; HLA TYPING; HUMAN; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; MALE; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES; ATAXIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIADIN; HLA-DQ ANTIGENS; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; PERIPHERAL NERVOUS SYSTEM DISEASES; PROSPECTIVE STUDIES;

EID: 27444439818     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2004.058487     Document Type: Article

References (26)

1. Hadjivassiliou M, Gibson A, Davies-Jones GA, et al. Does cryptic gluten sensitivity play a part in neurological illness? Lancet 1996;347:369-71.
2. Combarros O, Infante J, Lopez-Hoyos M, et al. Celiac disease and idiopathic cerebellar ataxia. Neurology 2000;54:2346.
3. Abele M, Burk K, Schols L, et al. The aetiology of sporadic adult-onset ataxia. Brain 2002;125:961-8.
4. Hadjivassiliou M, Grunewald R, Sharrack B, et al. Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics. Brain 2003;126:685-91.
5. Bushara KO, Goebel SU, Shill H, et al. Gluten sensitivity in sporadic and hereditary cerebellar ataxia. Ann Neurol 2001;49:540-3.
6. Hadjivassiliou M, Grunewald RA, Chattopadhyay AK, et al. Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia. Lancet 1998;352:1582-5.
7. Wills AJ, Unsworth DJ. The neurology of gluten sensitivity: separating the wheat from the chaff. Curr Opin Neurol 2002;15:519-23.
8. Cross AH, Golumbek PT. Neurologic manifestations of celiac disease. Proven, or just a gut feeling? Neurology 2003;60:1566-8.
9. Unsworth DJ. Serological diagnosis of gluten-sensitivity enteropathy. J Clin Pathol 1996;49:704-11.
10. Lock RJ, Pitcher MC, Unsworth DJ. IgA anti-tissue transglutaminase as a diagnostic marker of gluten sensitive enteropathy. J Clin Pathol 1999;52:274-7.
11. Johnsen B, Fuglsang-Frederiksen A. Electrodiagnosis of polyneuropathy. Neurophysiol Clin 2000;30:339-51.
12. Lock RJ, Unsworth DJ. Immunoglobulins and immunoglobulin subclasses in the elderly. Ann Clin Biochem 2003;40:143-8.
13. Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to Serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992;39:225-35.
14. Olerup O, Aldener A, Fogdell A. HLA-DQB1 and -DQA1 typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours. Tissue Antigens 1993;41:119-34.
15. Haworth S, Sinnot P, Davidson J, et al. Population studies. Caucasian England normal. In: Terasaki P, Gjertson D, eds. HLA 1997. Los Angeles, UCLA Tissue Typing Laboratory, 1997:208.
16. Pellecchia MT, Scala R, Filla A, et al. Idiopathic cerebellar ataxia associated with celiac disease: lack of distinctive neurological features. J Neurol Neurosurg Psychiatry 1999;66:32-5.
17. Luostarinen LK, Collin PO, Peraaho MJ, et al. Coeliac disease in patients with cerebellar ataxia of unknown origin. Ann Med 2001;33:445-9.
18. Burk K, Bosch S, Muller CA, et al. Sporadic cerebellar ataxia associated with gluten sensitivity. Brain 2001;124:1013-9.
19. Abele M, Schols L, Schwartz S, et al. Prevalence of antigliadin antibodies in ataxia patients. Neurology 2003;60:1672-3.
20. Zubillaga P, Vidates MC, Zubillaga I, et al. HLA-DQA1 and HLA-DQB1 genetic markers and clinical presentation in celiac disease. J Pediatr Gastroenterol Nutr 2002;34:548-54.
21. Balas A, Vicario JL, Zambrano A, et al. Absolute linkage of celiac disease and dermatitis herpetiformis to HLA-DQ. Tissue Antigens 1997;50:52-6.
22. Bushara KO, Nance M, Gomez CM. Antigliadin antibodies in Huntingdon's disease. Neurology 2004;62:132-3.
23. Sanz ML, Prieto I, Garcia BE, et al. Diagnostic reliability considerations of specific IgE determination. J Investig Allergol Clin Immunol 1996;6:152-61.
24. Husby S, Oxelius VA, Teisner B, et al. Humoral immunity to dietary antigens in healthy adults Occurrence, isotype and IgG subclass distribution of serum antibodies to protein antigens. Int Arch Allergy Appl Immunol 1985;77:416-22.
25. Kruszewski J, Raczka A, Klos M, et al. High serum levels of allergen specific IgG-4 (asIgG-4) for common food allergens in healthy blood donors. Arch Immunol Ther Exp (Warsz) 1994;42:259-61.
26. Hadjivassiliou M, Davies-Jones GA, Sanders DS, et al. Dietary treatment of gluten ataxia. J Neurol Neurosurg Psychiatry 2003;74:1221-4.