Diastereoselectivity enhancement in the 1,3-cycloaddition of β-lactam aldehydes. Application to the synthesis of enantiopure indolizidinone amino esters

Journal of Organic Chemistry

Volumn 70, Issue 22, 2005, Pages 8890-8894

  Alcaide, Benito ^a   Almendros, Pedro ^b   Redondo, María C ^a   Ruiz, M Pilar ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; AMINO ACIDS; CARBON; ESTERS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

AMINO ESTERS; CYCLOADDITION REACTIONS; DIASTEREOSELECTIVITY; HOMOLOGATION;

ALDEHYDES;

ACETALDEHYDE; ALKALOID; AMINO ACID; AZETIDINONE DERIVATIVE; AZOMETHINE YLIDE; BETA LACTAM DERIVATIVE; ESTER; INDOLIZIDINE DERIVATIVE; INDOLIZIDINONE DERIVATIVE; PROLINE DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLOADDITION; DIASTEREOISOMER; ENANTIOMER; INFRARED SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS;

ACETATES; ALDEHYDES; AMINATION; AZO COMPOUNDS; BETA-LACTAMS; ESTERS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SILVER COMPOUNDS; STEREOISOMERISM;

EID: 27444436637     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051402y     Document Type: Article

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48. Full spectroscopic and analytical data for compounds not included in this Experimental Section are described in the Supporting Information.