Practical asymmetric synthesis of α-branched 2- piperazinylbenzylamines by 1,2-additions of organometallic reagents to N-tert-butanesulfinyl imines

Journal of Organic Chemistry

Volumn 70, Issue 22, 2005, Pages 8924-8931

  Jiang, Wanlong ^a   Chen, Chen ^a   Marinkovic, Dragan ^a   Tran, Joe A ^a   Chen, Caroline W ^a   Arellano, L Melissa ^a   White, Nicole S ^a   Tucci, Fabio C ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; CHARACTERIZATION; DEHYDRATION; ORGANOMETALLICS; SYNTHESIS (CHEMICAL); X RAY CRYSTALLOGRAPHY;

ACIDIC DEPROTECTION; ASYMMETRIC SYNTHESIS; NOVEL LIGANDS; ORGANOMETALLIC REAGENTS;

AMINES;

2 [4 (TERT BUTOXYCARBONYL)PIPERAZINYL]BENZYLIDENE TERT BUTANESULFINAMIDE DERIVATIVE; 2 PIPERAZINYLBENZYLAMINE DERIVATIVE; BENZYLAMINE DERIVATIVE; BENZYLIDENE DERIVATIVE; IMINE; LIGAND; MELANOCORTIN 4 RECEPTOR; N BUTOXYCARBONYL 2 PIPERAZINYLBENZYL TERT BUTANESULFINAMIDE DERIVATIVE; N TERT BUTANESULFINAMIDE; N TERT BUTANESULFINYLIMINE DERIVATIVE; N TERT BUTANESULFONAMIDE; ORGANOMETALLIC COMPOUND; REAGENT; SULFINAMIDE; SULFONAMIDE; TERT BUTANESULFINAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ACIDITY; ADDITION REACTION; ARTICLE; CRYSTAL STRUCTURE; DEPROTECTION REACTION; DESICCATION; DIASTEREOISOMER; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALDEHYDES; ALKYLATION; BENZYLAMINES; BUTANES; CARBON; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; IMINES; LITHIUM; MOLECULAR STRUCTURE; NITROGEN; STEREOISOMERISM; SULFUR;

EID: 27444436362     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051514p     Document Type: Article

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