Eosinophil-granule major basic protein, a C-type lectin, binds heparin

Biochemistry

Volumn 44, Issue 43, 2005, Pages 14152-14158

  Swaminathan, G Jawahar ^a,c   Myszka, David G ^b   Katsamba, Phinikoula S ^b   Ohnuki, Lyo E ^b   Gleich, Gerald J ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATES; CHEMICAL BONDS; CRYSTAL STRUCTURE; MEDICAL PROBLEMS; SUGARS; SURFACE PLASMON RESONANCE;

ASTHMA; EOSINOPHIL MAJOR BASIC PROTEIN (EMBP); EOSINOPHIL-GRANULE; HEPARIN DISACCHARIDE;

PROTEINS;

CALCIUM; CARBOHYDRATE; HEPARIN; LECTIN; MAJOR BASIC PROTEIN; PROTEOGLYCAN;

ALLERGIC DISEASE; ARTICLE; ASTHMA; BINDING SITE; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG PROTEIN BINDING; EOSINOPHIL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN FUNCTION; SURFACE PLASMON RESONANCE;

ANTICOAGULANTS; BINDING SITES; CALCIUM; CARBOHYDRATE CONFORMATION; CATIONS, DIVALENT; CRYSTALLOGRAPHY, X-RAY; DISACCHARIDES; EOSINOPHIL MAJOR BASIC PROTEIN; HEPARIN; KINETICS; LECTINS; PROTEIN CONFORMATION;

EID: 27444435851     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051112b     Document Type: Article

References (37)

1. Gleich, G. J., Jacoby, D. B., and Fryer, A. D. (1995) Eosinophil-associated inflammation in bronchial-asthma: A connection to the nervous system, Int. Arch. Allergy Immunol. 107, 205-207.
2. Wassom, D. L., Loegering, D. A., Solley, G. O., Moore, S. B., Schooley, R. T., Fauci, A. S., and Gleich, G. J. (1981) Elevated serum levels of the eosinophil granule major basic-protein in patients with eosinophilia, J. Clin. Invest. 67, 651-661.
3. Gleich, G. J., Frigas, E., Loegering, D. A., Wassom, D. L., and Steinmuller, D. (1979) Cytotoxic properties of the eosinophil major basic protein, J. Immunol. 123, 2925-2927.
4. Gleich, G. J (2000) Mechanisms of eosinophil-associated inflammation, J. Allergy Clin. Immunol. 105, 651-663.
5. Piliponsky, A. M., Pickholtz, D., Gleich, G. J., and Levi-Schaffer, F. (2001) Human eosinophils induce histamine release from antigen-activated rat peritoneal mast cells: A possible role for mast cells in late-phase allergic reactions, J. Allergy Clin. Immunol. 107, 993-1000.
6. Moy, J. N., Gleich, G. J., and Thomas, L. L. (1990) Noncytotoxic activation of neutrophils by eosinophil granule major basic-protein: Effect on superoxide anion generation and lysosomal-enzyme release, J. Immunol. 145, 2626-2632.
7. Abu-Ghazaleh, R. I., Gleich, G. J., and Prendergast, F. G. (1992) Interaction of eosinophil granule major basic-protein with synthetic lipid bilayers: A mechanism for toxicity, J. Membr. Biol. 128, 153-164.
8. Hastie, A. T., Loegering, D. A., Gleich, G. J., and Kueppers, F. (1987) The effect of purified human eosinophil major basic protein on mammalian ciliary activity, Am. Rev. Respir. Dis. 135, 848-853.
9. Swaminathan, G. J., Weaver, A. J., Loegering, D. A., Checkel, J. L., Leonidas, D. D., Gleich, G. J., and Acharya, K. R. (2001) Crystal structure of the eosinophil major basic protein at 1.8 Å: An atypical lectin with a paradigm shift in specificity, J. Biol. Chem. 276, 26197-26203.
10. Abu-Ghazaleh, R. I., Dunnette, S. L., Loegering, D. A., Checkel, J. L., Kita, H., Thomas, L. L., and Gleich, G. J. (1992) Eosinophil granule proteins in peripheral-blood granulocytes, J. Leukocyte Biol. 52, 611-618.
11. Gleich, G. J., Loegering, D. A., Mann, K. G., and Maldonado, J. E. (1976) Comparative properties of the Charcot-Leyden crystal protein and the major basic protein from human eosinophils, J. Clin. Invest. 57, 633-640.
12. Otwinowski, Z., and Minor, W. (1997) Processing of X-ray diffraction data collected in oscillation mode, Methods Enzymol. 276, 307-326.
13. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination, Acta Crystallogr. D54, 905-921.
14. Weis, W. L, Kahn, R., Fourme, R., Drickamer, K., and Hendrickson, W. A. (1991) Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing, Science 254, 1608-1615.
15. Graves, B. J., Crowther, R. L., Chandran, C., Rumberger, J. M., Li, S., Huang, K. S., Presky, D. H., Familletti, P. C., Wolitzky, B. A., and Burns, D. K. (1994) Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains, Nature 367, 532-538.
16. Hakansson, K., Lim, N. K., Hoppe, H. J., and Reid, B. M. (1999) Crystal structure of the trimeric α-helical coiled-coil and the lectin domains of human lung surfactant protein D, Structure 7, 255-264.
17. Boyington, J. C., Riaz, A. N., Patamawenu, A., Coligan, J. E., Brooks, A. G., and Sun, P. D. (1999) Structure of CD94 reveals a novel C-type lectin fold: Implications for the NK cell-associated CD94/NKG2 receptors, Immunity 10, 75-82.
18. Llera, A. S., Viedma, F., Sanchez-Madrid, F., and Tormo, J. (2000) Crystal structure of the C-type lectin-like domain from the human hematopoietic cell receptor CD69, J. Biol. Chem. 276, 7312-7319.
19. Natarajan, K., Sawicki, M. W., Margulies, D. H., and Mariuzza, R. A. (2000) Crystal structure of human CD69: A C-type lectin-like activation marker of hematopoetic cells, Biochemistry 39, 14779-14786.
20. Blundell, C. D., Mahoney, D. J., Almond, A., DeAngelis, P. L., Kahmann, J. D., Teriete, P., Pickford, A. R., Campbell, I. D., and Day, A. J. (2003) The link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding, J. Biol. Chem. 49, 49261-49270.
21. 2+-dependent animal lectins, Biochem. Soc. Trans. 21, 456-459.
22. Drickamer, K., and Taylor, M. E. (1993) Biology of animal lectins, Annu. Rev. Cell Biol. 9, 237-264.
23. Drickamer, K. (1992) Engineering galactose-binding activity into a C-type mannose-binding protein, Nature 360, 183-186.
24. Ng, K. K.-S., Drickamer, K., and Weis, W. I. (1996) Structural analysis of monosaccharide recognition by rat liver mannose-binding protein, J. Biol. Chem. 271, 663-674.
25. Weis, W. I., and Drickamer, K. (1996) Structural basis of lectin-carbohydrate recognition, Annu. Rev. Biochem. 65, 441-473.
26. Jacoby, D. B., Gleich, G. J., and Fryer, A. D. (1993) Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor, J. Clin. Invest. 91, 1314-1318.
27. Rochester, C. L., Ackerman, S. J., Zheng, T., and Elias, J. A. (1996) Eosinophil-fibroblast interactions. Granule major basic protein interacts with IL-1 and transforming growth factor-β in the stimulation of lung fibroblast IL-6-type cytokine production, J. Immunol. 156, 4449-4456.
28. Trocme, S. D., and Hallberg, C. (1993) Heparin prevents eosinophil granule major basic-protein inhibition of corneal epithelial wound-healing in the rat, Invest. Ophthalmol. Visual Sci. 34, 1317.
29. Butterworth, A. E., Wassom, D. L., Gleich, G. J., Loegering, D. A., and David, J. R. (1979) Damage to schistosomula of Schistosoma mansoni induced directly by eosinophil major basic protein, J. Immunol. 122, 221-229.
30. Hamed, R. R., Maharem, T. M., and El-Guindy, A. S. (1997) Proteoglycans from adult worms of Schistosoma haematobium, J. Helminthol. 71, 151-160.
31. Frigas, E., Loegering, D. A., and Gleich, G. J. (1980) Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium, Lab. Invest. 42, 35-43.
32. Frigas, E., Loegering, D. A., Solley, G. O., Farrow, G. M., and Gleich, G. J. (1981) Elevated levels of the eosinophil granule major basic-protein in the sputum of patients with bronchial-asthma, Mayo Clin. Proc. 56, 345-353.
33. Flavahan, N. A., Slifman, N. R., Gleich, G. J., and Vanhoutte, P. M. (1988) Human eosinophil major basic protein causes hyperreactivity of respiratory smooth muscle. Role of the epithelium, Am. Rev. Respir. Dis. 138, 685-688.
34. Furuyama, A., and Mochitate, K. (2000) Assembly of the exogenous extracellular matrix during basement membrane formation by alveolar epithelial cells in vitro, J. Cell Sci. 113, 859-868.
35. Li, D., Clark, C. C., and Myers, J. C. (2000) Basement membrane zone type XV collagen is a disulfide-bonded chondroitin sulfate proteoglycan in human tissue and cultured cells, J. Biol. Chem. 275, 22339-22347.
36. Esnouf, R. M. (1997) An extensively modified version of MOLSCRIPT that includes greatly enhanced coloring capabilities, J. Mol. Graphics 15, 132-134.
37. Barton, G. J. (1993) ALSCRIPT: A tool to format multiple alignments, Protein Eng. 6, 37-40.