The cDNA of mouse skeletal muscle transcribe for both isoforms 1 and 2 of acetylcholine receptor alpha subunit

Journal of Neuroimmunology

Volumn 169, Issue 1-2, 2005, Pages 177-179

  Saini, Shamsher S ^a   Tüzün, Erdem ^a   Christadoss, Premkumar ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Acetylcholine receptor alpha subunit; Autoimmunity; cDNA; Human rabdomyosarcoma cell line TE671; Myasthenia gravis; Ocular muscle; P3A exon; RT PCR; Skeletal muscle

Indexed keywords

CHOLINERGIC RECEPTOR; COMPLEMENTARY DNA; MESSENGER RNA;

ALPHA CHAIN; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL LINE; CONTROLLED STUDY; EXTRAOCULAR MUSCLE; GEL ELECTROPHORESIS; LIMB; MOUSE; MYOSARCOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVERSE TRANSCRIPTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE;

ANIMALS; BLOTTING, NORTHERN; CELL LINE, TUMOR; CLONING, MOLECULAR; DNA, COMPLEMENTARY; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; MYOSARCOMA; PROTEIN ISOFORMS; RECEPTORS, CHOLINERGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 27344459274     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.08.013     Document Type: Article

References (14)

1. D. Beeson, A. Morris, A. Vincent, and J. Newsom-Davis The human muscle nicotinic acetylcholine receptor α-subunit exists as two isoforms: a novel exon EMBO J. 9 1990 2101 2106
2. P. Christadoss, M. Poussin, and C. Deng Animal models of myasthenia gravis Clin. Immunol. 94 2000 75 87
3. D.B. Drachman Myasthenia gravis N. Engl. J. Med. 330 1994 1797 1810
4. A.G. Engel, A.H. Lambert, and F.M. Howard Immune complexes (IgG and C3) at the motor end-plate in myasthenia gravis: ultrastructural and light microscopic localization and electrophysiologic correlations Mayo Clin. Proc. 52 1977 267 280
5. J.G. Haggerty, and S.C. Froehner Restoration of 125I-alpha-bungarotoxin binding activity to the alpha subunit of Torpedo acetylcholine receptor isolated by gel electrophoresis in sodium-dodecyl sulfate J. Biol. Chem. 256 1981 8294 8297
6. C. MacLennan, D. Beeson, A. Vincent, and J. Newsom-Davis Human nicotinic acetylcholine receptor α-subunit isoforms: origins and expression Nucleic Acids Res. 21 1993 5463 5467
7. A. Morris, D. Beeson, L. Jacobson, F. Baggi, A. Vincent, and J. Newsom-Davis Two isoforms of the muscle acetylcholine receptor alpha-subunit are translated in the human cell line TE671 FEBS Lett. 295 1991 116 118
8. M. Noda, Y. Furutani, H. Takahashi, M. Toyosato, T. Tanabe, S. Shimizu, S. Kikyotani, T. Kayano, T. Hirose, S. Inayama, and S. Numa Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor Nature 305 1983 818 823
9. J. Patrick, and J. Lindstrom Autoimmune response to acetylcholine receptor Science 180 1973 871 872
10. T. Takai, M. Noda, M. Mishina, S. Shimizu, Y. Furutani, T. Kayano, T. Ikeda, T. Kubo, H. Takahashi, and T. Takahashi Cloning, sequencing and expression of cDNA for a novel subunit of acetylcholine receptor from calf muscle Nature 315 1985 761 764
11. S. Talib, T.B. Okarma, and J.S. Lebkowski Differential expression of human nicotinic acetylcholine receptor alpha subunit variants in muscle and non-muscle tissues Nucleic Acids Res. 21 1993 233 237
12. M. Tsujihata, T. Yoshimura, A. Satoh, I. Kinoshita, H. Matsuo, M. Mori, and S. Nagataki Diagnostic significance of IgG, C3, and C9 at the limb muscle motor end-plate in minimal myasthenia gravis Neurology 39 1989 1359 1363
13. E. Tuzun, B.G. Scott, E. Goluszko, S. Higgs, and P. Christadoss Genetic evidence for involvement of classical complement pathway in induction of experimental autoimmune myasthenia gravis J. Immunol. 171 2003 3847 3854
14. S.J. Tzartos, and J.M. Lindstrom Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits Proc. Natl. Acad. Sci. U. S. A. 77 1980 755 759