Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa

Life Sciences

Volumn 78, Issue 1, 2005, Pages 2-7

  Matsumoto, Kenjiro ^a   Horie, Syunji ^a   Takayama, Hiromitsu ^b   Ishikawa, Hayato ^b   Aimi, Norio ^b   Ponglux, Dhavadee ^c   Murayama, Toshihiko ^b   Watanabe, Kazuo ^b  

^a JOSAI INTERNATIONAL UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Opioid receptor; 7 Hydroxymitragynine; Antinociception; Morphine; Tolerance; Withdrawal

Indexed keywords

7 HYDROXYMITRAGYNINE; ANTINOCICEPTIVE AGENT; CYPRODIME; HERBACEOUS AGENT; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; NALTRINDOLE; NORBINALTORPHIMINE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG CROSS TOLERANCE; DRUG EFFECT; DRUG MECHANISM; DRUG TOLERANCE; HERB; MALE; MITRAGYNA; MITRAGYNA SPECIOSA; MOUSE; NONHUMAN; TAIL FLICK TEST; WITHDRAWAL SYNDROME;

ANALGESICS; ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MITRAGYNA; MODELS, MOLECULAR; MORPHINANS; MORPHINE; NALOXONE; NALTREXONE; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; REACTION TIME; SECOLOGANIN TRYPTAMINE ALKALOIDS; SUBSTANCE WITHDRAWAL SYNDROME; THAILAND;

ANIMALIA; MITRAGYNA; MITRAGYNA SPECIOSA;

EID: 27344459171     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.10.086     Document Type: Article

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