-
1
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, Fleming T, Eiermann W, Wolter J, Pegram M, Baselga J, Norton L: Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
Fleming, T.7
Eiermann, W.8
Wolter, J.9
Pegram, M.10
Baselga, J.11
Norton, L.12
-
2
-
-
0021688634
-
The neu oncogene: An erb-B-related gene encoding a 185 000-Mr tumour antigen
-
Schechter AL, Stern DF, Vaidyanathan L, Decker SJ, Drebin JA, Greene MI, Weinberg RA: The neu oncogene: an erb-B-related gene encoding a 185 000-Mr tumour antigen. Nature 1984;312:513-516.
-
(1984)
Nature
, vol.312
, pp. 513-516
-
-
Schechter, A.L.1
Stern, D.F.2
Vaidyanathan, L.3
Decker, S.J.4
Drebin, J.A.5
Greene, M.I.6
Weinberg, R.A.7
-
3
-
-
0010066582
-
A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma
-
U S A
-
Semba K, Kamata N, Toyoshima K, Yamamoto T: A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci U S A 1985;82:6497-6501.
-
(1985)
Proc Natl Acad Sci
, vol.82
, pp. 6497-6501
-
-
Semba, K.1
Kamata, N.2
Toyoshima, K.3
Yamamoto, T.4
-
4
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
Coussens L, Yang-Feng TL, Liao YC, Chen E, Gray A, McGrath J, Seeburg PH, Libermann TA, Schlessinger J, Francke U, Levinson A, Ullrich A: Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985;230:1132-1139.
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
Chen, E.4
Gray, A.5
McGrath, J.6
Seeburg, P.H.7
Libermann, T.A.8
Schlessinger, J.9
Francke, U.10
Levinson, A.11
Ullrich, A.12
-
5
-
-
3543024857
-
Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen
-
U S A
-
Drebin JA, Link VC, Weinberg RA, Greene MI: Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen. Proc Natl Acad Sci U S A 1986;83:9129-9133.
-
(1986)
Proc Natl Acad Sci
, vol.83
, pp. 9129-9133
-
-
Drebin, J.A.1
Link, V.C.2
Weinberg, R.A.3
Greene, M.I.4
-
6
-
-
0022406444
-
Amplification of a novel v-erbB-related gene in a human mammary carcinoma
-
King CR, Kraus MH, Aaronson SA: Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 1985;229:974-976.
-
(1985)
Science
, vol.229
, pp. 974-976
-
-
King, C.R.1
Kraus, M.H.2
Aaronson, S.A.3
-
7
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
8
-
-
0026610881
-
Humanization of an anti-p185HER2 antibody for human cancer therapy
-
U S A
-
Carter P, Presta L, Gorman CM, Ridgway JB, Henner D, Wong WL, Rowland AM, Kotts C, Carver ME, Shepard HM: Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci U S A 1992;89:4285-4289.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 4285-4289
-
-
Carter, P.1
Presta, L.2
Gorman, C.M.3
Ridgway, J.B.4
Henner, D.5
Wong, W.L.6
Rowland, A.M.7
Kotts, C.8
Carver, M.E.9
Shepard, H.M.10
-
9
-
-
0029991439
-
Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
Baselga J, Tripathy D, Mendelsohn J, Baughman S, Benz CC, Dantis L, Sklarin NT, Seidman AD, Hudis CA, Moore J, Rosen PP, Twaddell T, Henderson IC, Norton L: Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol 1996;14:737-744.
-
(1996)
J Clin Oncol
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
10
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D, Robert NJ, Scholl S, Fehrenbacher L, Wolter JM, Paton V, Shak S, Lieberman G, Slamon DJ: Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-2648.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
Robert, N.J.4
Scholl, S.5
Fehrenbacher, L.6
Wolter, J.M.7
Paton, V.8
Shak, S.9
Lieberman, G.10
Slamon, D.J.11
-
11
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel CL, Cobleigh MA, Tripathy D, Gutheil JC, Harris LN, Fehrenbacher L, Slamon DJ, Murphy M, Novotny WF, Burchmore M, Shak S, Stewart SJ, Press M: Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:719-726.
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
12
-
-
0028200221
-
Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
-
Pietras RJ, Fendly BM, Chazin VR, Pegram MD, Howell SB, Slamon DJ: Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene 1994;9:1829-1838.
-
(1994)
Oncogene
, vol.9
, pp. 1829-1838
-
-
Pietras, R.J.1
Fendly, B.M.2
Chazin, V.R.3
Pegram, M.D.4
Howell, S.B.5
Slamon, D.J.6
-
13
-
-
0031903646
-
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
-
Pegram MD, Lipton A, Hayes DF, Weber BL, Baselga JM, Tripathy D, Baly D, Baughman SA, Twaddell T, Glaspy JA, Slamon DJ: Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 1998;16:2659-2671.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2659-2671
-
-
Pegram, M.D.1
Lipton, A.2
Hayes, D.F.3
Weber, B.L.4
Baselga, J.M.5
Tripathy, D.6
Baly, D.7
Baughman, S.A.8
Twaddell, T.9
Glaspy, J.A.10
Slamon, D.J.11
-
14
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: The M77001 study group
-
Marty M, Cognetti F, Maraninchi D, Snyder R, Mauriac L, Tubiana-Hulin M, Chan S, Grimes D, Anton A, Lluch A, Kennedy J, O'Byrne K, Conte P, Green M, Ward C, Mayne K, Extra JM: Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. J Clin Oncol 2005;23:4265-4274.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
Snyder, R.4
Mauriac, L.5
Tubiana-Hulin, M.6
Chan, S.7
Grimes, D.8
Anton, A.9
Lluch, A.10
Kennedy, J.11
O'Byrne, K.12
Conte, P.13
Green, M.14
Ward, C.15
Mayne, K.16
Extra, J.M.17
-
15
-
-
2442639836
-
Moving forward: Herceptin® in the adjuvant setting
-
Tan-Chiu E, Piccart M: Moving forward: Herceptin® in the adjuvant setting. Oncology 2002;63(suppl 1):57-63.
-
(2002)
Oncology
, vol.63
, Issue.1 SUPPL.
, pp. 57-63
-
-
Tan-Chiu, E.1
Piccart, M.2
-
16
-
-
28044452929
-
Docetaxel and cyclophosphamide followed by paclitaxel with or without trastuzumab as adjuvant therapy for patients with HER2-positive operative breast cancer. Combined analysis of NSABP-B-31 and NCCTG-N9831
-
May 13-17, Orlando, Florida. Oral presentation during symposium. Advances in Monoclonal Antibody Therapy for Breast Cancer
-
Romond E, Perez EA, Bryant J, et al.: Docetaxel and cyclophosphamide followed by paclitaxel with or without trastuzumab as adjuvant therapy for patients with HER2-positive operative breast cancer. Combined analysis of NSABP-B-31 and NCCTG-N9831. Program and abstracts of the 41st Annual Meeting of the American Society of Clinical Oncology; May 13-17, 2005; Orlando, Florida. Oral presentation during symposium. Advances in Monoclonal Antibody Therapy for Breast Cancer. http://www.asco.org/ac/1,1003,_12-002511-00_18-0034-00_19-005816, 00.asp.
-
(2005)
Program and Abstracts of the 41st Annual Meeting of the American Society of Clinical Oncology
-
-
Romond, E.1
Perez, E.A.2
Bryant, J.3
-
17
-
-
25144498287
-
Advances in monoclonal antibody therapy for breast cancer. HERA trial
-
May 13-17, Orlando, Florida. Oral presentation during symposium, Advances in Monoclonal Antibody Therapy for Breast Cancer
-
Piccart-Gebhart MJ; the Breast International Group: Advances in monoclonal antibody therapy for breast cancer. HERA trial. Program and abstracts of the 41st Annual Meeting of the American Society of Clinical Oncology; May 13-17, 2005; Orlando, Florida. Oral presentation during symposium, Advances in Monoclonal Antibody Therapy for Breast Cancer. http://www.asco.org/ac/ 1,1003,_12-002511-00_18-0034-00_19-005816,00.asp.
-
(2005)
Program and Abstracts of the 41st Annual Meeting of the American Society of Clinical Oncology
-
-
Piccart-Gebhart, M.J.1
-
18
-
-
27244442145
-
Safety and efficacy of trastuzumab every 3 weeks combined with cytotoxic chemotherapy in patients with HER-2 positive recurrent breast cancer: Findings from a case series
-
Ardavanis A, Tryfonopoulos D, Orfanos G, Karamouzis M, Scorilas A, Alexopoulos A, Rigatos G: Safety and efficacy of trastuzumab every 3 weeks combined with cytotoxic chemotherapy in patients with HER-2 positive recurrent breast cancer: findings from a case series. Onkologie 2005;28:558-564.
-
(2005)
Onkologie
, vol.28
, pp. 558-564
-
-
Ardavanis, A.1
Tryfonopoulos, D.2
Orfanos, G.3
Karamouzis, M.4
Scorilas, A.5
Alexopoulos, A.6
Rigatos, G.7
-
19
-
-
17144371333
-
Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule
-
Baselga J, Carbonell X, Castaneda-Soto NJ, Clemens M, Green M, Harvey V, Morales S, Barton C, Ghahramani P: Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule. J Clin Oncol 2005;23:2162-2171.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2162-2171
-
-
Baselga, J.1
Carbonell, X.2
Castaneda-Soto, N.J.3
Clemens, M.4
Green, M.5
Harvey, V.6
Morales, S.7
Barton, C.8
Ghahramani, P.9
-
20
-
-
0346017700
-
Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel
-
Leyland-Jones B, Gelmon K, Ayoub JP, Arnold A, Verma S, Dias R, Ghahramani P: Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel. J Clin Oncol 2003;21:3965-3971.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3965-3971
-
-
Leyland-Jones, B.1
Gelmon, K.2
Ayoub, J.P.3
Arnold, A.4
Verma, S.5
Dias, R.6
Ghahramani, P.7
-
21
-
-
24944542869
-
Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 weeks
-
Green MC, Buzdar AU, Smith T, Ibrahim NK, Valero V, Rosales MF, Cristofanilli M, Booser DJ, Pusztai L, Rivera E, Theriault RL, Carter C, Frye D, Hunt KK, Symmans WF, Strom EA, Sahin AA, Sikov W, Hortobagyi GN: Weekly paclitaxel improves pathologic complete remission in operable breast cancer when compared with paclitaxel once every 3 weeks. J Clin Oncol 2005;23:5983-5992.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5983-5992
-
-
Green, M.C.1
Buzdar, A.U.2
Smith, T.3
Ibrahim, N.K.4
Valero, V.5
Rosales, M.F.6
Cristofanilli, M.7
Booser, D.J.8
Pusztai, L.9
Rivera, E.10
Theriault, R.L.11
Carter, C.12
Frye, D.13
Hunt, K.K.14
Symmans, W.F.15
Strom, E.A.16
Sahin, A.A.17
Sikov, W.18
Hortobagyi, G.N.19
-
22
-
-
21844480293
-
CALGB 9840: Phase III study of weekly (W) paclitaxel (P) via 1-hour(h) infusion versus standard (S) 3h infusion every third week in the treatment of metastatic breast cancer (MBC), with trastuzumab (T) for HER2 positive MBC and randomized for T in HER2 normal MBC
-
ASCO Annual Meeting Proceedings (Post-Meeting Edition)
-
Seidman A D, Berry D, Cirrincione C, Harris L, Dressler L, Muss H, Naughton M, Norton L, Winer E, Hudis C: CALGB 9840: Phase III study of weekly (W) paclitaxel (P) via 1-hour(h) infusion versus standard (S) 3h infusion every third week in the treatment of metastatic breast cancer (MBC), with trastuzumab (T) for HER2 positive MBC and randomized for T in HER2 normal MBC. ASCO Annual Meeting Proceedings (Post-Meeting Edition). J Clin Oncol 2004;22(July 15 Suppl):512.
-
(2004)
J Clin Oncol
, vol.22
, Issue.JULY 15 SUPPL.
, pp. 512
-
-
Seidman, A.D.1
Berry, D.2
Cirrincione, C.3
Harris, L.4
Dressler, L.5
Muss, H.6
Naughton, M.7
Norton, L.8
Winer, E.9
Hudis, C.10
|