Long-term results of a randomized trial on extended use of high dose L-asparaginase for standard risk childhood acute lymphoblastic leukemia

Journal of Clinical Oncology

Volumn 23, Issue 28, 2005, Pages 7161-7167

  Pession, Andrea ^a   Valsecchi, Maria Grazia ^b   Masera, Giuseppe ^b   Kamps, Willem A ^b   Magyarosy, Edina ^b   Rizzari, Carmelo ^b   Van Wering, Elisabeth R ^b   Lo Nigro, Luca ^b   Van Der Does, Anna ^b   Locatelli, Franco ^b   Basso, Giuseppe ^b   Aricò, Maurizio ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ASPARAGINASE; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; DOXORUBICIN; FOLINIC ACID; MERCAPTOPURINE; METHOTREXATE; PREDNISONE; TIOGUANINE; VINCRISTINE; ANTINEOPLASTIC AGENT;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER RISK; CANCER SURVIVAL; CELL COUNT; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ACUTE LYMPHOCYTIC LEUKEMIA; AGE; DISEASE FREE SURVIVAL; DRUG ADMINISTRATION; FOLLOW UP; INFANT; MULTICENTER STUDY; PRESCHOOL CHILD; TREATMENT OUTCOME;

ADOLESCENT; AGE FACTORS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ASPARAGINASE; CHILD; CHILD, PRESCHOOL; DISEASE-FREE SURVIVAL; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; TREATMENT OUTCOME;

EID: 27244447048     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2005.11.411     Document Type: Article

References (23)

1. Conter V, Aricò M, Valsecchi MG, et al: Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) Acute Lymphoblastic Leukemia Studies, 1982-1995. Leukemia 14:2196-2204, 2000
2. Silverman LB, Declerck L, Gelber RD, et al: Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981-1995). Leukemia 14:2247-2256, 2000
3. Gaynon PS, Trigg ME, Heerema NA, et al: Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983-1995. Leukemia 14:2223-2233, 2000
4. Harms DO, Janka-Schaub GE: Co-operative study group for childhood acute lymphoblastic leukemia (COALL): Long-term follow-up of trials 82, 85, 89 and 92. Leukemia 14:2234-2239, 2000
5. Kamps WA, Veerman AJ, van Wering ER, et al: Long-term follow-up of Dutch Childhood Leukemia Study Group (DCLSG) protocols for children with acute lymphoblastic leukemia, 1984-1991. Leukemia 14:2240-2246, 2000
6. Pui CH, Boyett JM, Rivera GK, et al: Long-term results of Total Therapy studies 11, 12 and 13A for childhood acute lymphoblastic leukemia at St Jude Children's Research Hospital. Leukemia 14:2286-2294, 2000
7. Pui CH, Sandlund JT, Pei D, et al: Improved outcome for children with acute lymphoblastic leukemia: Results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Blood 104:2690-2696, 2004
8. Tallal L, Tan C, Oettgen H, et al: E. coli L-asparaginase in the treatment of leukemia and solid tumors in 131 children. Cancer 25:306-320, 1970
9. Sallan SE, Hitchcock-Bryan S, Gelber R, et al: Influence of intensive asparaginase in the treatment of childhood non-T-cell acute lymphoblastic leukemia. Cancer Res 43:5601-5607, 1983
10. Clavell LA, Gelber RD, Cohen HJ, et al: Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia. N Engl J Med 315:657-663, 1986
11. Asselin BL, Whitin JC, Coppola DJ, et al: Comparative pharmacokinetic studies of three asparaginase preparations. J Clin Oncol 11:1780-1786, 1993
12. Boos J, Werber G, Ahlke E, et al: Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations. Eur J Cancer 32A:1544-1550, 1996
13. Asselin BL, Kreissman S, Coppola DJ, et al: J: Prognostic significance of early response to a single dose of asparaginase in childhood acute Lymphoblastic leukemia. J Pediatr Hematol Oncol 21:6-12, 1999
14. Muller HJ, Boos J: Use of L-asparaginase in childhood ALL. Crit Rev Oncol Hematol 28:97-113, 1998
15. Riehm H, Gadner H, Henze G, et al: Acute lymphoblastic leukemia: Treatment results in three BFM studies (1970-1981), in Murphy SB, Gilbert JR (eds): Leukemia research: Advances in cell biology and treatment. Elsevier, New York, NY, 1983, pp 251-260
16. Riehm H, Reiter A, Schrappe M, et al: The in vivo response on corticosteroid therapy as an additional prognostic factor in childhood acute lymphoblastic leukemia (therapy study ALL-BFM 83). Klin Paediat 199:151-160, 1987
17. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
18. Cox DR: Regression models and life tables. J R Stat Soc 34:187-202, 1972
19. Conter V, Arico M, Valsecchi MG, et al: Extended intrathecal methotrexate may replace cranial irradiation for prevention of CNS relapse in children with intermediate-risk acute lymphoblastic leukemia treated with Berlin-Frankfurt- Münster-based intensive chemotherapy: The Associazione Italiana di Ematologia ed Oncologia Pediatrica. J Clin Oncol 13:2497-2502, 1995
20. Schrappe M, Reiter A, Ludwig W-D, et al: For the German-Austrian-Swiss ALL-BFM Study Group: Improved outcome in childhood ALL despite reduced use of anthracyclines and of cranial radiotherapy-Results of trial ALL-BFM 90. Blood 95:3310-3320, 2000
21. Rizzari C, Valsecchi MG, Arico M, et al: For the Associazione Italiano Ematologia Oncologia Pediatrica: Effect of protracted high-dose L-asparaginase given as a second exposure in a Berlin-Frankfurt-Munster-based treatment-Results of the randomized 9102 intermediate-risk childhood acute lymphoblastic leukemia study: A report from the Associazione Italiana Ematologia Oncologia Pediatrica. J Clin Oncol 19:1297-1303, 2001
22. Duval M, Suciu S, Ferster A, et al: Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: Results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial. Blood 99:2734-2739, 2002
23. Valsecchi MG, Masera G: A new challenge in clinical research in childhood ALL: The prospective meta-analysis strategy for intergroup collaboration. Ann Oncol 7:1005-1008, 1996