Cerebral circulation dynamics following fasudil intravenous infusion: A CT perfusion study

Brain and Nerve

Volumn 57, Issue 9, 2005, Pages 779-783

  Ono, Kenichiro ^a   Shirotani, Toshiki ^a   Yuba, Koji ^b   Yamana, Daigo ^b  

^a Japan Self Defense Force Central Hospital   (Japan)

^b Mishuku Hospital   (Japan)

Author keywords

Cerebral blood flow; Cerebral vasospasm; CT perfusion; Fasudil hydrochloride; Subarachnoid hemorrhage

Indexed keywords

FASUDIL;

ADULT; AGED; ARTICLE; BRAIN BLOOD VOLUME; BRAIN CIRCULATION; BRAIN PERFUSION; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DRUG ACTIVITY; FEMALE; HUMAN; MALE; SUBARACHNOID HEMORRHAGE; VASOSPASM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADULT; AGED; BRAIN; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PERFUSION; SUBARACHNOID HEMORRHAGE; TOMOGRAPHY, X-RAY COMPUTED; VASOSPASM, INTRACRANIAL;

EID: 27244436943     PISSN: 00068969     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Asano T, Ikegaki I, Satoh S, Mochizuki D, Hidaka H, Suzuki Y, Shibuya M, Sugita K: Blockade of intracellular actions of calcium may protect against ischemic damage to the gerbil brain. Br J Pharmacol 103: 1935-1938, 1991
2. Eastwood JD, Lev MH, Azhari T, Lee TY, Barboriak DP, Delong DM, Fitzek C, Herzau M, Wintermark M, Meuli R, Brazier D, Provenzale JM: CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke. Radiology 222: 227-236, 2002
3. Esteban JM, Cervera V: Perfusion CT and angio CT in the assessment of acute stroke. Neuroradiology 46: 705-715, 2004
4. Harrigan MR, Magnano CR, Guterman LR, Hopkins LN: Computed tomographic perfusion in the management of aneurysmal subarachnoid hemorrhage: new application of an existent technique. Neurosurgery 56: 304-317, 2005
5. Maiese K, Wagner J, Boccone L: Nitric oxide: a downstream mediator of calcium toxicity in the ischemic cascade. Neurosci Lett 166: 43-47, 1994
6. Nagumo H, Sasaki Y, Ono Y, Okamoto H, Seto M, Takuwa Y: Rho kinase inhibitor HA 1077 prevents Rho-mediated myosin phosphatase inhibition in smooth muscle cells. Am J Physiol Cell Physiol 278: C57-C65, 2000
7. Nambu K, Takehara R, Terada T: A method of regional cerebral blood perfusion measurement using dynamic CT with an iodinated contrast medium. Acta Neurol Scand (Supple) 166: 28-31, 1996
8. No Shinkei Geka 33: 133-140, 2005
9. Satoh S, Kobayashi T, Hitomi A, Ikegaki I, Suzuki Y, Shibuya M, Yoshida J, Asano T: Inhibition of neutrophil migration by a protein kinase inhibitor for the treatment of ischemic brain infarction. Jpn J Pharmacol 80: 41-48, 1999
10. Satoh S, Suzuki Y, Ikegaki I, Asano T, Shibuya M, Sugita K, Hidaka H: The effects of HA1077 on the cerebral circulation after subarachnoid haemorrhage in dogs. Acta Neurochir (Wien) 110: 185-188, 1991
11. Shibuya M, Suzuki Y, Sugita K, Saito I, Sasaki T, Takakura K, Okamoto S, Kikuchi H, Takemae T, Hidaka H: Dose escalation trial of a novel calcium antagonist, AT877, in patients with aneurysmal subarachnoid haemorrhage. Acta Neurochir (Wien) 107: 11-15, 1990
12. Shibuya M, Suzuki Y, Takayasu M, Asano M, Harada T, Ikegaki I, Satoh S, Hidaka H: The effects of an intracellular calcium antagonist HA 1077 on delayed cerebral vasospasm in dogs. Acta Neurochir (Wien) 90: 53-59, 1988
13. Shibuya M, Suzuki Y, Sugita K, Saito I, Sasaki T, Takakura K, Nagata I, Kikuchi H, Takemae T, Hidaka H, Nakashima M: Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage: results of a prospective placebo-controlled double-blind trial. J Neurosurg 76: 571-577, 1992
14. Tachibana E, Harada T, Shibuya M, Saito K, Takayasu M, Suzuki Y, Yoshida J: Intra-arterial infusion of fasudil hydrochloride for treating vasospasm following subarachnoid haemorrhage. Acta Neurochir (Wien) 141: 13-19, 1999
15. Tanaka K, Minami H, Kota M, Kuwamura K, Kohmura E: Treatment of cerebral vasospasm with intra-arterial fasudil hydrochloride. Neurosurgery 56: 214-223, 2005
16. Toshima Y, Satoh S, Ikegaki I, Asano T, Suzuki Y, Shibuya M: Thromboxane A2 synthetase inhibitor failed to ameliorate the arterial narrowing the chronic phase of cerebral vasospasm. Life Sci 61: 1371-1377, 1997
17. Wintermark M, Thiran JP, Maeder P, Schnyder P, Meuli R: Simultaneous measurement of regional cerebral blood flow by perfusion CT and stable xenon CT. AJNR Am J Neuroradiol 22: 905-914, 2001