Oxcarbazepine in infants and young children with partial seizures

Pediatric Neurology

Volumn 33, Issue 5, 2005, Pages 337-344

  Northam, Ralph S ^a   Hernandez, Angel W ^b   Litzinger, Marcia J ^c   Minecan, Daniela N ^d   Glauser, Tracy A ^e   Mangat, Surinder ^f   Zheng, Cixuang ^f   Souppart, Claire ^f   Sturm, Yvonne ^f  

^a Monarch Research Associates   (United States)

^b Cook Children's Medical Center ^*  (United States)

^c Epilepsy and Neurodevelopment Inc   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^f NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; DRUG METABOLITE; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANEMIA; ANOREXIA; ARTICLE; ATAXIA; BLOOD SAMPLING; BRAIN ARACHNOID CYST; BRONCHIOLITIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DEHYDRATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ERUPTION; DRUG SAFETY; DRUG TOLERABILITY; EAR INFECTION; EPILEPTIC STATE; FATIGUE; FEMALE; FEVER; FOCAL EPILEPSY; GASTROINTESTINAL INFECTION; HUMAN; HYPERACTIVITY; HYPONATREMIA; INFANT; INSOMNIA; IRRITABILITY; LETHARGY; MALE; MONOTHERAPY; NOSE CONGESTION; OTITIS MEDIA; PHARYNGITIS; PNEUMONIA; POTASSIUM BLOOD LEVEL; PRESCHOOL CHILD; PRIORITY JOURNAL; RHINOPHARYNGITIS; SEIZURE; SIDE EFFECT; SOMNOLENCE; STREPTOCOCCUS INFECTION; TITRIMETRY; UPPER RESPIRATORY TRACT INFECTION; VIRUS INFECTION; VOMITING;

ANTICONVULSANTS; CARBAMAZEPINE; CHILD, PRESCHOOL; EPILEPSIES, PARTIAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; TREATMENT OUTCOME;

EID: 27144540545     PISSN: 08878994     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2005.05.011     Document Type: Article

References (18)

1. J.M. Pellock Treatment of seizures and epilepsy in children and adolescents Neurology 51 1998 S8 S14
2. R. Roberts, W. Rodriguez, D. Murphy, T. Crescenzi Pediatric drug labeling Improving the safety and efficacy of pediatric therapies JAMA 290 2003 905 911
3. M.J. McLean, M. Schmutz, A.W. Wamil, H.R. Olpe, C. Portet, K.F. Feldmann Oxcarbazepine Mechanisms of action Epilepsia 35 Suppl. 3 1994 S5 S9
4. A. Stefani, A. Pisani, M. De Murtas, N.B. Mercuri, M.G. Marciani, P. Calabresi Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. II. Modulation of high-voltage-activated calcium currents Epilepsia 36 1995 997 1002
5. L. Bang, K. Goa Oxcarbazepine A review of its use in children with epilepsy Paediatr Drugs 5 2003 557 573
6. M.M. Guerreiro, U. Vigonius, H. Pohlmann A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy Epilepsy Res 27 1997 205 213
7. T.A. Glauser, M. Nigro, R. Sachdeo The Oxcarbazepine Pediatric Study Group Adjunctive therapy with oxcarbazepine in children with partial seizures Neurology 54 2000 2237 2244
8. W.M. Sallas, S. Milosavljev, J. D'Souza, M. Hossain Pharmacokinetic drug interactions in children taking oxcarbazepine Clin Pharmacol Ther 74 2003 138 149
9. The Commission on Classification and Terminology of the International League Against Epilepsy Proposal for revised clinical and electroencephalographic classification of epileptic seizures Epilepsia 22 1981 489 501
10. P.A. Bill, U. Vigonius, H. Pohlmann A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy Epilepsy Res 27 1997 195 204
11. M.J. Brodie, A. Richens, A.W. Yuen UK Lamotrigine/Carbamazepine Monotherapy Trial Group Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy Lancet 345 1995 476 479
12. D.W. Chadwick, H. Anhut, M.J. Greiner International Gabapentin Monotherapy Study Group 945-77 A double-blind trial of gabapentin monotherapy for newly diagnosed partial seizures Neurology 51 1998 1282 1288
13. M. Dam, R. Ekberg, Y. Løyning, O. Waltimo, K. Jakobsen The Scandinavian Oxcarbazepine Study Group A double-blind study comparing oxcarbazepine and carbamazepine in patients with newly diagnosed, previously untreated epilepsy Epilepsy Res 3 1989 70 76
14. Y. Mikaeloff, A. Saint-Martin, J. Mancini Topiramate Efficacy and tolerability in children according to epilepsy syndromes Epilepsy Res 53 2003 225 232
15. B. Bourgeois Extensive clinical experience with oxcarbazepine (Trileptal) in children with epilepsy demonstrates good safety and tolerability profiles Ann Neurol 54 Suppl. 7 2003 S136
16. E. Gaily, M.L. Granstrom, E. Liukkonen Oxcarbazepine in the treatment of early childhood epilepsy J Child Neurol 12 1997 496 498
17. J. Van Parys Oxcarbazepine (Trileptal) has no effect on vital signs and electrocardiograms Epilepsia 43 Suppl. 8 2002 149
18. ©) monotherapy in pediatric patients with inadequately-controlled partial seizures An open-label pilot study Eur J Neurol 10 Suppl. 1 2003 148 (abstr. P2082)