The implantation of every embryo facilitates the chances of the remaining embryos to implant in an IVF programme: A mathematical model to predict pregnancy and multiple pregnancy rates

Human Reproduction

Volumn 20, Issue 10, 2005, Pages 2923-2931

  Matorras, Roberto ^a,d   Matorras, Francisco ^b   Mendoza, Rosario ^a   Rodríguez, Manuel ^c   Remohí, José ^c   Rodríguez Escudero, Francisco J ^a   Simón, Carlos ^c  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

^d NONE   (Spain)

Author keywords

Collaborative model; Embryo implantation; Mathematical model; Multiple pregnancy; Prediction formula

Indexed keywords

ACCURACY; ARTICLE; BINOMIAL DISTRIBUTION; EMBRYO; EMBRYO TRANSFER; FAMILY COUNSELING; FEMALE; FERTILIZATION IN VITRO; HUMAN; INFERTILITY; INTERNET; MATHEMATICAL MODEL; MULTIPLE PREGNANCY; NIDATION; OOCYTE DONATION; OUTCOMES RESEARCH; PREDICTION; PREGNANCY RATE; PROBABILITY; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SPAIN; VALIDATION PROCESS;

EID: 27144534225     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dei129     Document Type: Article

References (31)

1. Altman DG (1991) Practical Statistics for Medical Research. Chapman and Hall, London/NewYork.
2. Baker HWG, Saunders DM, Tyler JPP, Lamont B, Burge D, Fiske L, Oke K and Johnston IH (2000) Difficulties in comparison of results between assisted reproductive technology clinics: An attempt to standarize reporting. Reprod Technol 10,103-111.
3. Bollen N, Camus M, Tournaye H, Wisanto A, Van Steirleghem AC and Devorey P (1993) Embryo reduction in triplet pregnancies after assisted procreation: A comparative study. Fertil Steril 60,504-549.
4. Caballero-Campo P, Domínguez F, Coloma J, Meseguer M, Remohí J, Pellicer A and Simon C (2002) Hormonal and embryonic regulation of chemokines IL-8, MCP-1 and RANTES in the human endometrium during the window of implantation. Mol Hum Reprod 8,375-384.
5. Caligara C, Navarro J, Vargas G, Simon C, Pellicer A and Remohi J (2001) The effect of repeated controlled ovarian stimulation in donors. Hum Reprod 16,320-323.
6. De los Santos MJ, Mercader A, Frances A, Portoles E, Remohi J, Pellicer A and Simon C (1996) Immunoreactive human embryonic interleukin-1 system and endometrial factors regulating their secretion during embryonic development. Biol Reprod 54,563-574.
7. De Placido G, Wilding M, Strina I, Alviggi E, Alviggi C, Mollo A, Varicchio MT, Tolino A, Schiattarella C and Dale B (2002) High outcome predictability after IVF using a combined score for zygote and embryo morphology and growth rate. Hum Reprod 17,2402-2409.
8. ESHRE Campus Course Report (2001) Prevention of twin pregnancies after IVF/ICSI by single embryo transfer. Hum Reprod 16,790-800.
9. Fazleabas A, Donnelly KM, Srinivasan S, Fortman JD and Miller JB (1999) Modulation ofthe baboon (Papio anubis) uterine endometrium by chorionic gonadotrophin during the period of uterine receptivity. Proc Natl Acad Sci USA 96,2543-2548.
10. Galan A, O'Connor E, Valbuena D, Herrer R, Remohi J, Pampfer S, Pellicer A and Simon C (2000) The human blastocyst regulates endometrial epithelial apoptosis in embryonic adhesion. Biol Reprod 63,430-439.
11. Gerris J, De Neubourg D, Mangelschots K, Van Royen E, Vercruyssen M, Barudy-Vasquez J, Valkenburg M and Ryckaert G (2002) Elective single day 3 embryo transfer halves the twinning rate without decrease in the ongoing pregnancy rate of an IVF/ICSI programme. Hum Reprod 17,2626-2631.
12. González RR, Caballero-Campo P, Jasper M, Mercader A, Devoto L, Pellicer A and Simon C (2000) Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocyst. J Clin Endocrinol Metab 85,4883-4888.
13. Harper MJK, Kudolo GB, Alecozay AA and Jones MA (1989) Platelet activating factor (PAF) and blastocyst-endometrial interactions. Prog Clin Biol Res 294,305-315.
14. Hunault CC, Eijkemans MJ, Pieters MH, te Velde ER, Habbema JD, Fauser BC and Macklon NS (2002) A prediction model for selecting patients undergoing in vitro fertilization for elective single embryo transfer. Fertil Steril 77,725-732.
15. Martikainen, H, Tiitinen A, Tomas C, Tapanainen J, Orava M, Tuomivaara L, Vilska S, Hyden-Granskog C, Hovatta O and the Finnish ET Study Group (2001) One versus two embryo transfer after IVF and ICSI: A randomized study. Hum Reprod 16,1900-1903.
16. Martin PM and Welch HG (1998) Probabilities for singleton and multiple pregnancies after in vitro fertilization. Fertil Steril, 70478-481.
17. Matorras R, Urquijo E, Mendoza R, Corcóstegui B, Expósito A and Rodríguez-Escudero FJ (2002) Ultrasound-guided embryo transfer improves pregnancy rates and increases the frequency of easy transfers. Hum Reprod 17,1767-1772.
18. Meseguer M, Aplin D, Caballero-Campo P, O'Connor JE, Martín JC, Remohi J, Pellicer A and Simon C (2001) Human endometrial mucin MUC1 is upregulated by progesterone and down-regulated in vitro by the human blastocyst. Biol Reprod 64,181-192.
19. Ozturk O and Templeton A (2002) In-vitro fertilisation and risk of multiple pregnancy. Lancet 359,232.
20. Ozturk O, Bhattacharya S and Templeton A (2001) Avoiding multiple pregnancies in ART: Evaluation and implementation of new strategies. Hum Reprod 16,1319-1321.
21. Ruiz A, Remohi J, Minguez Y, Guanes PP, Simon C and Pellicer A (1997) The role of in vitro fertilization and intracytoplasmic sperm injection in couples with unexplained infertility after failed intrauterine insemination. Fertil Steril 68,171-173.
22. SART Assisted Reproductive Technology Success Rates (1997) National Summary and Fertility Clinic Reports. http://wwwcdcgov/nccdphp/drh/ archive/art97/prefacehtm.
23. Seoud MAF, Toner JP, Kruithoff C and Muasher SJ (1992) Outcome of twins, triplet and quadruplet in vitro fertilization pregnancies: The Norfolk experience. Fertil Steril 57,825-834.
24. Shiotani M, Noda Y, Mori T (1993) Embryo-dependent induction of uterine receptivity assessed by an in vitro model of implantation in mice. Biol Reprod 49,794-801.
25. 1 in human endometrial epithelial cells in vitro. J Clin Endocrinol Metab 82,2607-2616.
26. Speirs AL, Baker HWG and Abdullah N (1996) Analysis of factors affecting embryo implantation. Hum Reprod 11(Suppl 1), 187-191.
27. Terriou P, Sapin C, Giorgetti C, Hans E, Spach JL and Roulier R (2001) Embryo score is a better predictor of pregnancy than the number of transferred embryos or female age. Fertil Steril 75,525-531.
28. Trimarchi JR (2001) A mathematical model for predicting which embryos to transfer - an illusion of control or a powerful tool? Fertil Steril 76,1286-1287.
29. Wakuda K, Takakura K, Nakanishi K, Kita N, Shi H, Hirose M and Noda Y (1999) Embryo-dependent induction of embryo receptivity in the mouse endometrium. J Reprod Fertil 115,315-324.
30. Wheeler CA, Cole BF, Frishman GN, Seifer DB, Lovegreen SB and Hackett RJ (1998) Predicting probabilities of pregnancy and multiple gestation from in vitro fertilization - a new model. Obstet Gynecol 91,696-700.
31. Yaron Y, Bryant-Greenwood PK, Dave N, Moldenhauer JS, Kramer RL, Johnson MP and Evans MI (1999) Multifetal reductions of triplets to twins: comparison with nonreduced triplets and twins. Am J Obstet Gynecol 180,1268-1271.