Are Dexamethasone Suppression Test nonsuppression and thyroid dysfunction related to a family history of dementia in patients with major depression? An exploratory study

Canadian Journal of Psychiatry

Volumn 50, Issue 6, 2005, Pages 342-345

  Fountoulakis, Konstantinos N ^a,b   Kaprinis, Stergios G ^a   Iacovides, Apostolos ^a   Phokas, Konstantinos ^a   Kaprinis, George ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b NONE   (Greece)

Author keywords

Depression; Psychoneuroendocrinology; Thyroid function

Indexed keywords

DEXAMETHASONE; HYDROCORTISONE; LIOTHYRONINE; MICROSOME ANTIBODY; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; THYROID ANTIBODY; THYROTROPIN; THYROXINE; DIAGNOSTIC AGENT; GLUCOCORTICOID;

ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMENTIA; DEXAMETHASONE SUPPRESSION TEST; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EXPLORATORY RESEARCH; FAMILY HISTORY; FEMALE; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HORMONE DETERMINATION; HUMAN; HYDROCORTISONE BLOOD LEVEL; MAJOR DEPRESSION; MALE; MULTIVARIATE ANALYSIS OF COVARIANCE; POST HOC ANALYSIS; QUANTITATIVE ANALYSIS; RELATIVE; STUDENT T TEST; THYROGLOBULIN BLOOD LEVEL; THYROID DISEASE; THYROID FUNCTION TEST; THYROTROPIN BLOOD LEVEL; DRUG EFFECT; GENETICS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; THYROID GLAND;

ADULT; DEMENTIA; DEPRESSIVE DISORDER, MAJOR; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; THYROID DISEASES; THYROID FUNCTION TESTS; THYROID GLAND;

EID: 27144528383     PISSN: 07067437     EISSN: 14970015     Source Type: Journal    
DOI: 10.1177/070674370505000609     Document Type: Article

References (17)

1. Graves A, White E, Koepsel T. The association between head trauma and Alzheimer's disease. Am J Epidemiol 1990;131:491-501.
2. Heyman A, Wilkinson W, Stafford J. Alzheimer's disease: a study of epidemiological aspects. Ann Neurol 1984;15:335-41.
3. Tsolaki M, Fountoulakis K, Chantzi H, Kazis A. Risk factors for clinically diagnosed Alzheimer's disease: a case-control study in a Greek elderly population. Int Psychogeriatr 1997;3:327-41.
4. Wing J, Babor T, Brugha T. SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Arch Gen Psychiatry 1990;47:589-93.
5. Mavreas V. Greek version of the World Health Organisation: Schedules for Clinical Assessment in Neuropsychiatry-SCAN. Version 2.0. 1995. Located at: Research University Institute for Mental Health, Athens.
6. Loranger A, Sartorious N, Andreoli A. The World Health Organisation/Alcohol, Drug Abuse and Mental Health Administration International Pilot Study of Personality Disorders. Arch Gen Psychiatry 1994;51:215-24.
7. World Health Organisation. International Personality Disorders Examination. Geneva: WHO; 1995.
8. Fountoulakis K, Iacovides A, Kaprinis G, Ierodiakonou C. Greek translation of the World Health Organisation: International Personality Disorders Examination. 1998. Located at: 3rd Department of Psychiatry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
9. Fountoulakis K, Iacovides A, Ioannidou C, Bascialla F, Nimatoudis I, Kaprinis G, and others. Reliability and cultural applicability of the Greek version of the International Personality Disorders Examination. BMC Psychiatry 2002;2(1):6.
10. Andreasen N. The measurment of genetic aspects of depression. In: Marsella A, Hirschfeld R, Katz M, editors. The measurement of depression. New York: John Wiley & Sons; 1987. p 87-108.
11. Carroll B, Martin F, Davies B. Resistance of suppression by dexamethasone of plasma 11-OHCS levels in severe depressive illness. BMJ 1968;3:285-7.
12. Staner L, De La Fuente J, Kerkhofs M, Linkowski P, Mendlewicz J. Biological and clinical features of recurrent brief depression: a comparison with major depressed and healthy subjects. J Affect Disord 1992;26:241-5.
13. Legros S, Mendlewicz J, Wybran J. Immunoglobulins, autoantibodies and other serum protein fractions in psychiatric disorders. Eur Arch Psychiatry Neurol Sci 1985; 235(1):9-11.
14. Rao M, Ruhrmann S, Retey B, Liappis N, Fuger J, Kraemer M, and others. Low plasma thyroid indices of depressed patients are attenuated by antidepressant drugs and influence treatment outcome. Pharmacopsychiatry 1996;29:180-6.
15. Musselman DL, Nemeroff CB. Depression and endocrine disorders: focus on the thyroid and adrenal system. Br J Psychiatry Suppl 1996;(30):123-8.
16. Aronson R, Offman HJ, Joffe RT, Naylor CD. Triiodothyronine augmentation in the treatment of refractory depression: a meta-analysis. Arch Gen Psychiatry 1996;53:842-8.
17. Genovesi G, Paolini P, Marcellini L, Vernillo E, Salvati G, Polidori G, and others. Relationship between autoimmune thyroid disease and Alzheimer's disease. Panminerva Med 1996; 38(1):61-3.