Gender differences in pain and biomechanical responses after acid sensitization of the human esophagus

Digestive Diseases and Sciences

Volumn 50, Issue 11, 2005, Pages 2050-2058

  Reddy, Hariprasad ^a,b   Arendt Nielsen, Lars ^b   Staahl, Camilla ^a,b   Pedersen, Jan ^a   Funch Jensen, Peter ^c   Gregersen, Hans ^a,b   Drewes, Asbjørn Mohr ^a,b  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b AALBORG UNIVERSITY   (Denmark)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Acid sensitization; Esophagus; Experimental pain; Gender; Mechanical; Thermal stimulation

Indexed keywords

HYDROCHLORIC ACID;

ADULT; ARTICLE; BIOMECHANICS; CHEMICAL ANALYSIS; COLD; COMPARATIVE STUDY; CORRELATION ANALYSIS; ESOPHAGUS; FEMALE; GASTROINTESTINAL DISEASE; HUMAN; HYPERACTIVITY; HYPERALGESIA; MALE; PAIN; PRIORITY JOURNAL; SEX DIFFERENCE; THERMAL STIMULATION;

ADULT; COLD; ESOPHAGUS; FEMALE; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; MUSCLE CONTRACTION; PAIN; PAIN MEASUREMENT; PHYSICAL STIMULATION; SEX CHARACTERISTICS;

EID: 27144489658     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-005-3006-x     Document Type: Article

References (59)

1. Berkley KJ: Sex differences in pain. Behav Brain Sci 20:371-380, 1997
2. Fillingim RB, Edwards RR, Powell T: The relationship of sex and clinical pain to experimental pain responses. Pain 83:419-425, 2004
3. Riley JL III, Robinson ME, Wise EA, Myers CD, Fillingim RB: Sex differences in the perception of noxious experimental stimuli: a meta-analysis. Pain 74:181-187, 1998
4. Fillingim RB, Maixner W: Gender differences in the responses to noxious stimuli. Pain Forum 4:209-221, 1995
5. Giamberardino MA, Berkley KJ, Iezzi S, de Bigontina P, Vecchiet L: Pain threshold variations in somatic wall tissues as a function of menstrual cycle, segmental site and tissue depth in non-dysmenorrheic women, dysmenorrheic women and men, Pain 71:187-197, 1997
6. Giamberardino MA: Sex-related and hormonal modulation of visceral pain. In Sex, Gender and Pain. Seattle, IASP Press, 2000, pp 135-164
7. Cairns BE, Hu JW, Arendt-Nielsen L, Sessle BJ, Svensson P: Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle. J Neurophysiol 86(2):782-791, 2001
8. Hutson WR, Roehrkasse RL, Wald A: Influence of gender and menopause on gastric emptying and motility Gastroenterology 96(1):11-17, 1989
9. Ter RB: Gender differences in gastroesophageal reflux disease. J Gend Specif Med 3(2):42-44, 2000
10. Arendt-Nielsen L: Induction and assessment of experimental pain from human skin, muscle, and viscera. In Proceedings of the 8th World Congress of Pain, Progress in Pain Research and Management. Jensen TS, Turner JA, Wiesenfeld-Hallin Z (eds). Seattle, ISAP Press, 1997, pp 393-125
11. Drewes AM, Gregersen H, Arendt-Nielsen L: Experimental pain in gastroenterology: A reappraisal of human studies. Scand J Gastroenterol 38:1115-1130, 2003
12. Jackson NA, Houghton LA, Whorwell PJ, Currer : Does the menstrual cycle affect anorectal physiology? Dig Dis Sci 39(12):2607-2611, 1994
13. Soffer EE, Kongara K, Achkar JP, Gannon J: Colonic motor function in humans is not affected by gender Dig Dis Sci 45(7):1281-1284, 2000
14. Sloots CE, Felt-Bersma RJ, Cuesta MA, Meuwissen SG: Rectal visceral sensitivity in healthy volunteers: influences of gender, age and methods Neurogastroenterol Motil 12(4):361-368, 2000
15. Gregersen H: Biomechanics of the Gastrointestinal Tract. London, Springer Verlag, 2002.
16. Pedersen J, Reddy H, Funch-Jensen P, Arendt-Nielsen L, Gregersen H, Drewes AM: Differences between male and female responses to painful thermal and mechanical stimulation of the human esophagus. Dig Dis Sci 491065-1074, 2004
17. Fass R, Sampliner RE, Mackel C, McGee D, Rappaport W: Age- and gender-related differences in 24-hour esophageal pH monitoring of normal subjects. Dig Dis Sci 38:1926-1928, 1993
18. Richter JE, Bradley LA, DeMeester TR, Wu WC: Normal 24-hr ambulatory esophageal pH values. Influence of study center, pH electrode, age, and gender. Dig Dis Sci 37:849-856, 1992
19. Ter RB, Castell DO: Influence of age and gender on gastroesophageal reflux in symptomatic patients. Dis Esophagus 11:106-108, 1998
20. Gregersen H, Andersen MB: Impedance measuring system for cross-sectional area in the gastrointestinal tract. Med Biol Eng Comput 29:108-110, 1991
21. Gregersen H, Giversen IM, Rasmussen LM, Tottrup A: Biomechanical wall properties and collagen content in the partially obstructed opossum esophagus Gastroenterology 103(5):1547-1551, 1992
22. Gao C, Petersen P, Liu W, Arendt-Nielsen L, Drewes AM, Gregersen H: Sensory-motor responses to volume-controlled duodenal distension Neurogastroenterol Motil 14(4):365-374, 2002
23. Drewes AM, Schipper KP, Dimcevski G, et al.: Multimodal assessment of pain in the esophagus: a new experimental model Am J Physiol Gastrointest Liver Physiol 283(1):G95-G103, 2002
24. Drewes AM, Pedersen J, Liu W, Arendt-Nielsen L, Gregersen H: Controlled mechanical distension of the human oesophagus: Sensory and biomechanical findings. Scand J Gastroenterol 38:27-35, 2003
25. Pedersen J, Gao C, Egekvist H, et al.: Pain and biomechanical responses to distension of the duodenum in patients with systemic sclerosis. Gastroenterology 124: 1230-1239, 2003
26. Petersen P, Gao C, Rössel P, Qvist P, Arendt-Nielsen L, Gregersen H: Sensory and biomechanical responses to distension of the normal human rectum and sigmoid colon. Digestion 64:191-199, 2001
27. Bernstein LM, Baker LA: A clinical test for esophagitis. Gastroenterology 34:760-781, 1958
28. Nguyen P, Lee SD, Castell DO: Evidence of gender differences in esophageal pain threshold Am J Gastroenterol 90(6):901-905, 1995
29. Mearadji B, Penning C, Vu MK, van der Schaar PJ, van Petersen AS, Kamerling IM et al. Influence of gender on proximal gastric motor and sensory function. Am J Gastroenterol 96(7):2066-2073, 2001
30. Whitehead WE, Delvaux M: Standardization of barostat procedures for testing smooth muscle tone and sensory thresholds in the gastrointestinal tract. The Working Team of Glaxo-Wellcome Research, UK. Dig Dis Sci 42(2):223-241, 1997
31. Gregersen H, Orvar K, Christensen J: Biomechanical properties of duodenal wall and duodenal tone during phase I and phase II of the MMC. Am J Physiol 263:G795-G801, 1992
32. Triadafilopoulos G, Tsang HP, Segall GM: Hot water swallows improve symptoms and accelerate esophageal clearance in esophageal motility disorders. J Clin Gastroenterol 26:239-244, 1998
33. Sengupta J.N., Gebhart G.F: Gastrointestinal afferent fibers and sensation. In Physiology of the Gastrointestinal Tract. Johnson L (ed). New York, Raven Press, 1994, pp 484-519
34. Drewes AM, Schipper K-P, Dimcevski G, et al.: Multi-oesophagus. Eur J Pain 7:539-549, 2003
35. Bajaj P, Arendt-Nielsen L, Bajaj P, Madsen H: Sensory changes during the ovulatory phase of the menstrual cycle in healthy women. Eur J Pain 5:135-144, 2001
36. Curatolo M, Arendt-Nielsen L, Petersen-Felix S: Evidence, mechanisms, and clinical implications of central hypersensitivity in chronic pain after whiplash injury. Clin J Pain 20:469-476, 2004
37. Poulsen L, Arendt-Nielsen L, Brosen K, Nielsen KK, Gram LF, Sindrup SH: The hypoalgesic effect of imipramine in different human experimental pain models. Pain 60:287-293, 1995
38. Pedersen J, Reddy H, Funch-Jensen P, Arendt-Nielsen L, Gregersen H, Drewes AM: Differences between male and female responses to painful thermal and mechanical stimulation of the human esophagus. Dig Dis Sci 49:1065-1074, 2004
39. Nguyen P, Lee SD, Castell DO: Evidence of gender differences in esophageal pain threshold. Am J Gastroenterol 90:901-905, 1995
40. Shirazi S, Schulze-Delrieu K, Custer-Hagen T, Brown CK, Ren J: Motility changes in opossum esophagus from experimental esophagitis. Dig Dis Sci 34:1668-1676, 1989
41. Sarkar S, Hobson AR, Furlong PL, Woolf CJ, Thompson DG, Aziz Q: Central neural mechanisms mediating human visceral hypersensitivity Am J Physiol Gastrointest Liver Physiol 281:G1196-G1202, 2001
42. Leonard R, Johnson DH, Alpers, Christensen J, Jacobsen E: Physiology of the Gastrointestinal Tract. New York, Raven Press, 1994
43. Kern MK, Jaradeh S, Arndorfer RC, Jesmanowicz A, Hyde J, Shaker R: Gender differences in cortical representation of rectal distension in healthy humans. Am J Physiol Gastrointest Liver Physiol 281:G1512-G1523, 2001
44. Christensen J: Origin of sensation in the esophagus. Am J Physiol Gastrointest Liver Physiol 246:G221-G225, 1984
45. Christensen J, Williams TH, Jew J, O'Dorisio TM: Distribution of immunoreactive substance P in opossum esophagus. Dig Dis Sci 34:513-520, 1989
46. Pedersen J, Reddy H, Punch-Jensen P, Arendt-Nielsen L, Gregersen H, Drewes AM: Cold and heat pain assessment of the human oesophagus after experimental sensitisation with acid. Pain 110:393-399, 2004
47. Caterina MJ: Vanilloid receptors take a TRP beyond the sensory afferent. Pain 105:5-9, 2003
48. Maggi CA: The dual, sensory and "efferent" function of the capsaicin-sensitive primary sensory neurons in the urinary bladder and uretra. In Nervous Control of the Urogenital System. Maggi CA (ed). Chur: Harwood Academic Publishers GmbH, Poststrasse 22, 7000 Chur, Switzerland, 1993, pp 382-422
49. Arendt-Nielsen L, Laursen RJ, Drewes AM: Referred pain as an indicator for neural plasticity Prog Brain Res 129:343-356, 2000
50. Coderre TJ, Katz J, Vaccarino AL, Melzack R: Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence [see comments]. Pain 52:259-285, 1993
51. Kern MK, Jaradeh S, Arndorfer RC, Jesmanowicz A, Hyde J, Shaker R: Gender differences in cortical representation of rectal distension in healthy humans. Am J Physiol Gastrointest Liver Physiol 281:G1512-G1523, 2001
52. Lebars D, Dickenson AH, Besson JM: Diffuse noxious inhibitory controls (DNIC). 1. Effects on dorsal horn convergent neurons in the rat. Pain 6:283-304, 1979
53. Ren K, Dubner R: Descending modulation in persistent pain: an update. Pain 100:1-6, 2002
54. Ness TJ, Gebhart GF: Characterization of neurons responsive to noxious colorectal distension in the T13-L2 spinal cord of the rat. J Neurophysiol 60:1419-1438, 1988
55. Roza C, Laird JM, Cervero F: Spinal mechanisms underlying persistent pain and referred hyperalgesia in rats with an experimental ureteric stone. J Neurophysiol 79:1603-1612, 1998
56. Serrao M, Rossi P, Sandrini G, Parisi L, Amabile GA, Nappi G : Effects of diffuse noxious inhibitory controls on temporal summation of the RIII reflex in humans. Pain 112:353-360, 2004
57. Locke GR III, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ III: Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology 112:1448-1456, 1997
58. Nilsson M, Johnsen R, Ye W, Hveem K, Lagergren J: Prevalence of gastro-oesophageal reflux symptoms and the influence of age and sex. Scand J Gastroenterol 39:1040-1045, 2004
59. Thompson WG, Irvine EJ, Pare P, Ferrazzi S, Rance L: Functional gastrointestinal disorders in Canada: first population-based survey using Rome II criteria with suggestions for improving the questionnaire. Dig Dis Sci 47:225-235, 2002