Study on the efficiency of hard gelatin capsules coating in a spouted bed

Drying Technology

Volumn 23, Issue 9-11, 2005, Pages 2039-2053

  Oliveira, Helder V A ^a   Peixoto, Maria P G ^a   Freitas, Luis A P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Fluid dynamics; Methacrylic polymer; Stability; Suspension viscosity

Indexed keywords

CHEMICAL EQUIPMENT; COATING TECHNIQUES; DRUG PRODUCTS; ORGANIC POLYMERS; STABILITY; SUSPENSIONS (FLUIDS); VISCOSITY OF LIQUIDS;

HARD GELATIN CAPSULES; METHACRYLIC POLYMER; SPOUTED BED; SUSPENSION VISCOSITY;

FLUID DYNAMICS;

SPOUTED BED;

EID: 27144488158     PISSN: 07373937     EISSN: 15322300     Source Type: Journal    
DOI: 10.1080/07373930500210499     Document Type: Article

References (25)

1. Oliveira, H.V.A.; Freitas, L.A.P. Efficiency of the enteric coating of capsules. Proceedings of the XXX Brazilian Congress on Particulate Systems (COBRASP, ENEMP), São Carlos, SP, Brazil, October 20-23, 2002.
2. Donida, M.W.; Rocha, S.C.S. Coating of urea with an aqueous polymeric suspension in a two-dimensional spouted bed. Drying Technology 2002, 20 (3), 685-704.
3. Queiroz-Filho, A.V.; Piccolo, S.V.; Rocha, S.C.S. Evaluation of the tablets coating in a 2-dimensional spouted bed using 3 atomization positions. In Proceedings of XXIV Brazilian Congress on Particulate Systems (COBRASP, ENEMP), Uberlândia, MG, Brazil, October 21-24, 1996; Vol. 1, 93-98.
4. Rocha, S.C.S. Coating of tablets. In Special Topics in Drying, 1st Ed.; Freire, J.T.; Sartori, D.J.M., Eds.; Universidade Federal de São Carlos: São Carlos, São Paulo, Brazil, 1992; 295-330.
5. Prista, L.N.; Alves, A.C.; Morgado, R. Pharmaceutical Technic and Galenic Pharmacy, 4th Ed.; Fundação Calouste Gulbenkian, Lisboa, 1996; 659-864.
6. Huyghebaert, N.; Na Vermeire, J.P.R. Alternative method for enteric coating of HPMC capsules resulting in ready-to-use enteric-coated capsules. European Journal of Pharmaceutical Scienes 2004, 21 (5), 617-623.
7. Passos, M.L.; Mujumdar, A.S.; Raghavan, V.G.S. Spouted beds for drying: Principles and design considerations. Advances in Drying 1987, 4, 359-398.
8. Kucharski, J.; Kmiec, A. Hydrodynamics, heat and mass transfer during coating of tablets in spouted bed. Canadian Journal Chemical Engineering 1983, 61 (3), 435-439.
9. Kucharski, J.; Kmiec, A. Analysis of Simultaneous Drying and Coating of Tablets in a Spouted Bed. In Proceedings of the XV International Drying Symposium. Cambridge, MA, August 13-16, 1996, Vol. 2, 204-217.
10. Kucharski, J.; Kmiec, A. Kinetics of granulation process during coating of tablets in a spouted bed. Chemical Engineering Science 1989, 44 (8), 1627-1636.
11. Rocha, S.C.S.; Ayub, G.E. Transferência de calor gás-particula no recobrimento de comprimidos em leito de jorro bidimensional. Proceedings of the XXI Congress on Particulate Systems (COBRASP, ENEMP), Ouro Preto, MG, October 20-22, 1993.
12. Oliveira, W.P.; Koury, J.R.; Freire, J.T. Analysis of particle coating by spouted bed process. International Journal Pharmaceutics 1997, 158 (1), 1-9.
13. Freitas, L.A.P.; Freire, J.T. Development of a spouted bed coater for tablets. In Proceedings of the II Congress European sur la Fluidisation. Bilbao, Spain, September 8-11, 1997.
14. Publio, M.C.P.; Aguiar, M.L.; Oliveira, W.P. Application of gastric resistant coating on tablets by the Wuster process. In Proceedings of 3rd European Thermal Sciences Conference, Edizioni ETS, Heidelberg, Germany, September 10-13,2000.
15. Espinaço, A.L.; Kfuri, C.R.; Freitas, L.A.P. A study on the coating efficiency in spouted bed. In Proceedings of the XXIX Congress on Particulate Systems (COBRASP, ENEMP), São João Del Rey, MG, Brazil, October 14-17, 2001.
16. Espinaço, A.L.; Freitas, L.A.P. Release kinetic of spouted bed coated tablets. In Proceedings of the XXX Congress on Particulate Systems (COBRASP, ENEMP), UFSCar, São Carlos, SP, Brazil, 2002.
17. Oliveira, W.P.; Freire, J.T. Aspectos tecnológicos dos processos de recobrimento de partículas. In Proceedings of XXI Congress on Particulate Systems (COBRASP, ENEMP), Campinas, SP, Brazil, October 15-17,1991.
18. USP XXIII. United States Pharmacopeia, 23rd Ed.; United States Pharmacopeial Convention: Rockville, MD, 1995.
19. Epstein, N.; Grace, J.R. Spouting of particulate solids. In Handbook of Powder Science & Technology; Fayed, M.E., Otten, L., Eds.; Van Nostrand Reinhold: New York, 1997; 5090-5536.
20. Box, M.; Hunter, W.G.; Hunter, J.S. Statistics for Experimenters, 1st Ed.; John Wiley & Sons: New York, 1978.
21. Cole, E.T. Enteric coated HPMC capsules designed to achieve intestinal targeting. International Journal of Pharmaceutics 2002, 231 (1), 83-95.
22. Zank, J.; Kind, M.; Schlünder, E.U. Particle growth in a continuously operated fluidized bed granulator. Drying Technology 2001, 19 (8), 1755-1772.
23. Aulton, M.E.; Hogan, J.E.; Twitchell, A.M. Physicochemical properties of HPMC and their role in the film coating process and the quality of coated product. In Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, 2nd Ed.; McGinity, J.W., Ed.; Marcel Dekker: New York, 1997; 227-266.
24. Mehta, A.H.; Enders, N.A.; Mahjour, M.; Fawzi, M.B. A comparative evaluation of aqueous enteric polymers in capsule coating. Pharmaceutical Technology 1986, 10 (10), 36-46.
25. Ghebre-Sellassie, I.; Nesbitt, R.U.; Wang, J. Eudragit aqueous dispersions as pharmaceutical controlled release coatings. In Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, 2nd Ed.; McGinity, J.W. Ed.; Marcel Dekker: New York, 1997.