Simvastatin has deleterious effects on human first trimester placental explants

Human Reproduction

Volumn 20, Issue 10, 2005, Pages 2866-2872

  Kenis, I ^a   Tartakover Matalon, Shelly ^a   Cherepnin, N ^a   Drucker, L ^a   Fishman, A ^a   Pomeranz, M ^a   Lishner, M ^a,b  

^a MEIR MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Migration; Pregnancy; Proliferation; Simvastatin; Trophoblast

Indexed keywords

CASPASE 3 INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; MATRIGEL; MEVALONIC ACID; MONOCLONAL ANTIBODY KI 67; SIMVASTATIN;

APOPTOSIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTROPHOBLAST; DRUG CONTRAINDICATION; ENZYME INHIBITION; EXPLANT; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MIGRATION INHIBITION; PHASE CONTRAST MICROSCOPE; PLACENTA FUNCTION; PLACENTAL TRANSFER; PREGNANCY COMPLICATION; PROGESTERONE RELEASE; TERATOGENICITY; TISSUE CULTURE; TISSUE PREPARATION; TROPHOBLAST;

ANIMALIA;

EID: 27144474896     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dei120     Document Type: Article

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