Formation of photoproducts and cytotoxicity of bilirubin irradiated with turquoise and blue phototherapy light

Acta Paediatrica, International Journal of Paediatrics

Volumn 94, Issue 10, 2005, Pages 1448-1454

  Roll, Ellen Bruzell ^a,b,c   Christensen, Terje ^a  

^a NORWEGIAN RADIATION PROTECTION AUTHORITY   (Norway)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c Nordisk Institutt for Odontologiske Materialer   (Norway)

Author keywords

Bilirubin; Photochemistry; Phototherapy; Phototoxicity; Wavelength

Indexed keywords

BILIRUBIN; BILIRUBIN DERIVATIVE; HUMAN SERUM ALBUMIN; LUMIRUBIN; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; APOPTOSIS; ARTICLE; BLUE LIGHT; CELL DAMAGE; CELL DEATH; CELL DIVISION; CELL GROWTH; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; GEOMETRY; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IRRADIATION; ISOMER; LIGHT; LIGHT EXPOSURE; LIGHT IRRADIANCE; LYMPHOMA CELL; MITOSIS INDEX; MOUSE; NONHUMAN; PHOTOCHEMISTRY; PHOTOOXIDATION; PHOTOTHERAPY; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TURQUOISE LIGHT;

ANIMALS; APOPTOSIS; BILIRUBIN; CELL DEATH; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLOR; MICE; PHOTOBIOLOGY; PHOTOSENSITIZING AGENTS; PHOTOTHERAPY; PROBABILITY; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 27144452320     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1080/08035250510032655     Document Type: Article

References (29)

1. Vecchi C, Donzelli GP, Migliorini MG, Sbrana G, Pratesi R. New light in phototherapy. Lancet 1982;14:390.
2. Ennever JF. Blue light, green light, white light, more light: treatment of neonatal jaundice. In: Maisels MJ, editor. Neonatal jaundice. Clin Perinatol 1990;17:467-81.
3. Onishi S, Itoh S, Isobe K. Wavelength dependence of the relative rate constants for the main geometric and structural photoisomerization of bilirubin IXα bound to human serum albumin. Biochem J 1986;236:23-9.
4. Sideris EG, Papageorgiou GC, Charalampous SC, Vitsa EM. A spectrum response study on single strand DNA breaks, sister chromatide exchanges, and lethality induced by phototherapy lights. Pediatr Res 1981;5:1019-23.
5. Rosenstein BS, Ducore JM, Cummings SW. The mechanism of bilirubin-photosensitized DNA strand breakage in human cells exposed to phototherapy light. Mutation Res 1983;112: 397-406.
6. Christensen T, Støttum A, Brunborg G, Reitan JB. Unwanted side effects and optimization of phototherapy. In: Douglas RH, Moan J, Dall'Acqua F, editors. Light in biology and medicine. 1st ed. New York: Plenum Press; 1988. p. 153-9.
7. Wu FY, Iijima K, Nishida A, Higurashi M. Sister chromatid exchanges in the peripherial lymphocytes of newborns with Down syndrome after in vitro exposure to blue or green light. Mutat Res 1996;367:261-4.
8. Donzelli GP, Pratesi S, Rapisardi G, Agati G, Fusi F, Pratesi R. 1-day phototherapy of neonatal jaundice with blue-green lamp. Lancet 1995;346:184-5.
9. Agati G, Pratesi R, Fusi F, Roll EB, Christensen T, Lindemann R, et al. Testing a fluorescent lamp for neonatal jaundice phototherapy [abstract]. In: Book of abstracts of the 9th Congress of the European Society for Photobiology; 2001 Sep. 3-8; Lillehammer, Norway. European Society for Photobiology; 2001. p. 111.
10. Ebbesen F, Agati G, Pratesi R. Phototherapy with turquoise versus blue light. Arch Dis Child Fetal Neonatal Ed 2003;88:F430-1.
11. Sisson TRC, Glauser SC, Glauser EM, Tasman W, Kuwabara T. Retinal changes produced by phototherapy. J Pediatrics 1970;77:221-7.
12. Christensen T. Cytotoxicity of bilirubin photoproducts. Photobiochem Photobiophys 1986;10:253-60.
13. Christensen T, Kinn G, Granli T, Amundsen I. Cells, bilirubin and light. Formation of photoproducts and cellular effects at denned wavelengths. Acta Paediatr 1994;83:7-12.
14. Christensen T, Kinn G, Gradzka I, Jaworska A, Roll EB. Photosensitizing effects of bilirubin. First Internet Conference on Photochemistry and Photobiology. Internet Journal of Science Biological Chemistry 1997 [cited April 2003];3. Available from URL: http://www.photobiology.com/v1/contrib/e42.htm
15. Christensen T, Roll EB, Jaworska A, Kinn G. Bilirubin- and light-induced cell death in a murine lymphoma cell line. J Photochem Photobiol B 2000;58:170-4.
16. Bruzell Roll, E. Bilirubin-induced cell death during continuous and intermittent phototherapy and in the dark. Acta Pediatr 2005;94:1437-42.
17. Li Y-J, Shackter E. Oxidative stress inhibits apoptosis in human lymphoma cells. J Biol Chem 1999;274:19792-8.
18. Agati G, Fusi F, Pratesi S, Galvan P, Donzelli GP. Bilirubin photoisomerization products in serum and urine from a Crigler-Najjar type I patient treated by phototherapy. J Photochem Photobiol B 1998;47:181-9.
19. Ennever JF, Knox I, Speck WT. Differences in bilirubin isomer composition in infants treated with green and white light phototherapy. J Clin Invest 1986;109:119-22.
20. McDonagh AF, Agati G, Fusi F, Pratesi R. Quantum yields for laser photocyclization of bilirubin in the presence of human serum albumin. Dependence of quantum yield on excitation wavelength. Photochem Photobiol 1989;50:305-9.
21. Agati G, Fusi F, Donzelli GP, Pratesi R. Quantum yield and skin filtering effects on the formation rate of lumirubin. J Photochem Photobiol B 1993;18:197-203.
22. Onishi S, Itoh S, Isobe K, Ochi M, Kunikata T, Imai T. Effect of the binding of bilirubin to either the first class or the second class of binding sites of the human serum albumin molecule on its photochemical reaction. Biochem J 1989;257: 711-4.
23. Malhotra V, Greenberg JW, Dunn IX, Ennever JF. Fatty acid enhancement of the quantum yield for the formation of lumirubin from bilirubin bound to human albumin. Pediatr Res 1987;21:530-3.
24. Christensen T, Kinn G. Bilirubin bound to cells does not form photoisomers. Acta Paediatr 1993;82:22-5.
25. Ennever JF, McDonagh AF, Speck WT. Phototherapy for neonatal jaundice: optimal wavelengths of light. J Pediatr 1983; 103:295-9.
26. Agati G, Fusi F, Pratesi R. Configurational photoisomerization of bilirubin "in vitro". II. A comparative study of phototherapy fluorescent lamps and lasers. Photochem Photobiol 1985; 41:381-92.
27. Troup GJ, Agati G, Fusi F, Pratesi R. Photophysics of the variable quantum yield of asymmetric bilirubin. Aust J Phys 1996;49:673-81.
28. Madsen LP. The effectiveness of eye protection during high-intensity phototherapy. Acta Paediatr 1993;82:91.
29. Matthes R, Bernhardt J, McKinlay A, editors. Guidelines on limiting exposure to non-ionizing radiation. Munich: International Commission on Non-Ionising Radiation Protection; 1999; ICNIRP 7/99.