Acute lymphoblastic leukemia in a patient with congenital neutropenia without G-CSF-R and ELA2 mutations [19]

Leukemia

Volumn 19, Issue 9, 2005, Pages 1710-1711

  Yetgin, S ^a   Germeshausen, M ^b   Touw, I ^c   Koc A ^a   Olcay, L ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT; CD19 ANTIGEN; CD20 ANTIGEN; CD22 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; ELASTASE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; HEMOGLOBIN; HLA DR ANTIGEN; IMMUNOGLOBULIN G; PANCREATIC ELASTASE II; SERINE PROTEINASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; B CELL LEUKEMIA; BACTERIAL INFECTION; BONE MARROW BIOPSY; CASE REPORT; DEATH; EOSINOPHIL; FEMALE; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN TISSUE; INFANT; LETTER; LEUKEMIA REMISSION; LEUKOCYTE COUNT; LYMPHOBLAST; LYMPHOCYTE; MONOCYTE; NEUTROPENIA; NEUTROPHIL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECURRENT INFECTION; SEPTICEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; DNA MICROARRAY; ENZYMOLOGY; GENETICS; METHODOLOGY;

FEMALE; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE; NEUTROPENIA; NEUTROPHILS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; SERINE ENDOPEPTIDASES;

EID: 26944451745     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2403850     Document Type: Letter

References (8)

1. Dong F, Dale DC, Bonilla MA, Freedman M, Fasth A, Neijens HJ et al. Mutations in the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia. Leukemia 1997; 11: 120-125.
2. Druhan LJ, Ai J, Massullo P, Kindwall-Keller T, Ranalli MA, Avalos BR. Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia. Blood 2005; 105: 584-591.
3. Freedman MH, Bonilla MA, Fier C, Bolyard AA, Scarlata D, Boxer LA et al. Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy. Blood 2000; 96: 429-436.
4. Dale DC, Person RE, Bolyard AA, Aprikyan AG, Bos C, Bonilla MA et al. Mutation in the gene encoding neutrophil elastase in congenital and cyclic neutropenia. Blood 2000; 96: 2317-2322.
5. Cassinat B, Bellanne-Chantelot C, Notz-Carrere A, Menot ML, Vaury C, Micheau M et al. Screening for G-CSF receptor mutations in patients with secondary myeloid or lymphoid transformation of severe congenital neutropenia. A report from the French Neutropenia Register. Leukemia 2004; 18: 1553-1555.
6. Germeshausen M, Ballmaier M, Schulze H, Welte K, Flohr T, Beiske K et al. Granulocyte colony-stimulating factor receptor mutations in a patient with acute lymphoblastic leukemia secondary to severe congenital neutropenia. Blood 2001; 97: 829-831.
7. Poncz M, Solowiejczyk D, Harpel B, Mory Y, Schwartz E, Surrey S. Construction of human gene libraries from small amounts of peripheral blood. Analysis of beta-like globin. Hemoglobin 1982; 6: 27-36.
8. Bellanne-Chantelot C, Clauin S, Leblanc T, Cassinat B, Rodrigues-Lima F, Beaufils S et al. Mutations in the ELA2 gene correlate with more severe expression of neutropenia: A study of 81 patients from French Neutropenia Register. Blood 2004; 103: 4119-4125.