The impact of nicotine on osseointegration: An experimental study in the femur and tibia of rabbits

Clinical Oral Implants Research

Volumn 16, Issue 4, 2005, Pages 389-395

  Balatsouka, Dimitra ^a   Gotfredsen, Klaus ^a   Lindh, Christian H ^b   Berglundh, Tord ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Bone healing; Histomorphometry; Implants; Nicotine; Removal torque test; Resonance frequency analysis; Smoking

Indexed keywords

COTININE; DIAGNOSTIC AGENT; FLUORESCENT DYE; GANGLION STIMULATING AGENT; NICOTINE; PLACEBO; TITANIUM;

ANIMAL; ARTICLE; BIOMECHANICS; BLOOD; BONE REGENERATION; CHEMISTRY; DRUG EFFECT; FEMALE; FEMUR; INFUSION PUMP; MECHANICAL STRESS; PATHOLOGY; RABBIT; SUBCUTANEOUS DRUG ADMINISTRATION; SURFACE PROPERTY; TIBIA; TOOTH IMPLANTATION; TORQUE; VIBRATION;

ANIMALS; BIOMECHANICS; COTININE; DENTAL IMPLANTS; FEMALE; FEMUR; FLUORESCENT DYES; GANGLIONIC STIMULANTS; INFUSION PUMPS; INJECTIONS, SUBCUTANEOUS; NICOTINE; OSSEOINTEGRATION; PLACEBOS; RABBITS; STRESS, MECHANICAL; SURFACE PROPERTIES; TIBIA; TITANIUM; TORQUE; VIBRATION;

EID: 26944445119     PISSN: 09057161     EISSN: 16000501     Source Type: Journal    
DOI: 10.1111/j.1600-0501.2004.01151.x     Document Type: Article

References (30)

1. Akhter, M.P., Iwaniec, U.T., Haynatzki, G.R., Fung, Y.K., Cullen, D.M. Recker, R.R. (2003) Effects of nicotine on bone mass and strength in aged female rats. Journal of Orthopaedic Research 21 : 14 19.
2. Bain, C.A. Moy, P.K. (1993) The association between the failure of dental implants and cigarette smoking. International Journal of Maxillofacial Implants 8 : 609 615.
3. Balatsouka, D., Gotfredsen, K., Lindh, C.H. Berglundh, T. (2005) The impact of nicotine on bone healing and osseointegration. An experimental study in rabbits. Clinical Oral Implants Research 16 : 268 276.
4. Benowitz, N.L. Jacob, P. III. (1994) Metabolism of nicotine to cotinine studied by a dual stable isotope method. Clinical Pharmacology and Therapeutics 56 : 483 493.
5. Cesar Neto, J.B., Duarte, P.M., Sallum, E.A., Barbieri, D., Moreno, H. Jr. Nociti, F.H. Jr. (2003) A comparative study on the effect of nicotine administration and cigarette smoke inhalation on bone healing around titanium implants. Journal of Periodontology 74 : 1454 9.
6. Ekfeldt, A., Christiansson, U., Eriksson, T., Linden, U., Lundqvist, S., Rundcrantz, T., Johansson, L.A., Nilner, K. Billström, C. (2001) A retrospective analysis of factors associated with multiple implant failures in maxillae. Clinical Oral Implants Research 12 : 462 467.
7. Esposito, M., Hirsch, J.M., Lekholm, U. Thomsen, P. (1998) Biological factors contributing to failures of osseointegrated oral implants (II). Etiopathogenesis. European Journal of Oral Sciences 106 : 721 764.
8. Friberg, B., Sennerby, L., Linden, B., Gröndahl, K. Lekholm, U. (1999) Stability measurements of one-stage Brånemark implants during healing in mandibles. A clinical resonance frequency study. International Journal of Oral and Maxillofacial Surgery 28 : 266 272.
9. Gorman, L.M., Lambert, P.M., Morris, H.F., Ochi, S. Winkler, S. (1994) The effect of smoking on implant survival at second-stage surgery: DICRG Interim Report No. 5. Implant Dentistry 3 : 165 168.
10. Gotfredsen, K., Nimb, L., Hjörting-Hansen, E., Jensen, J.S. Holmen, A. (1992) Histomorphometric and removal torque analysis for TiO2-blasted titanium implants. An experimental study on dogs. Clinical Oral Implants Research 3 : 77 84.
11. Hollinger, J.O., Schmitt, J.M., Hwang, K. Buck, D. (1999) Impact of nicotine on bone healing. Journal of Biomedical Materials Research 45 : 294 301.
12. Hultin, M., Fischer, J., Gustafsson, A., Kallus, T. Klinge, B. (2000) Factors affecting late fixture loss and marginal bone loss around teeth and dental implants. Clinical Oral Implants Research 2 : 203 208.
13. Ivanoff, C.J., Sennerby, L. Lekholm, U. (1996) Influence of mono-and bicortical anchorage on the integration of titanium implants. A study in the rabbit tibia. International Journal of Oral and Maxillofacial Surgery 25 : 229 235.
14. Johansson, C.B., Han, C.H., Wennerberg, A. Albrektsson, T. (1998) A quantitative comparison of machined commercially pure titanium and titanium-aluminium-vanadium implant in rabbit bone. International Journal of Oral & Maxillofacial Implants 13 : 315 321.
15. Kan, J.Y.K., Rungcharassaeng, K., Lozada, J.L. Goodacre, C.J. (1999) Effects of smoking on implant success in grafted maxillary sinuses. The Journal of Prosthetic Dentistry 82 : 307 311.
16. Lindquist, L.W., Carlsson, G.E. Jemt, T. (1997) Association between marginal bone loss around osseointegrated mandibular implants and smoking habits: a 10-year follow-up study. Journal of Dental Research 76 : 1667 1674.
17. Meredith, N. (1998) Assessment of implant stability as a prognostic determinant. The International Journal of Prosthodontics 11 : 491 501.
18. Meredith, N. (2000) Implant stability, function and clinical success, Resonance Frequency Analysis Symposium, Gothenburg, Sweden.
19. Meredith, N., Alleyne, D. Cawley, P. (1996) Quantitative determination of the stability of the implant-tissue interface using resonance frequency analysis. Clinical Oral Implants Research 7 : 261 267.
20. Nociti, F.H., Stefani, C.M., Sallum, E.A., Duarte, P.M. Sallum, A.W. (2002) Nicotine and bone density around titanium implants: a histometric study in rabbits. Implant Dentistry 11 : 176 182.
21. Patel, T.Ch., Erulkar, J.S., Grauer, J.N., Troiano, N.W., Panjabi, M.M. Friedlaender, G.E. (2001) Osteogenic Protein-1 overcomes the inhibitory effect of nicotine on posterolateral lumbar fusion. Spine 26 : 1656 1661.
22. Raikin, S.M., Landsman, J.C., Alexander, V.A., Froimson, M.I. Plaxton, N.A. (1998) Effect of nicotine on the rate and strength of long bone fracture healing. Clinical Orhopaedics and Related Research 353 : 231 237.
23. Schwartz Arad, D., Samet, N., Samet, N. Mamlider, A. (2002) Smoking and complications of endosseous dental implants. Journal of Periodontology 73 : 153 157.
24. Sennerby, L. Roos, J. (1998) Surgical determinants of clinical success of osseointegrated oral implants: a review of the literature. The International Journal of Prosthodontics 11 : 408 420.
25. Sennerby, L., Thomsen, P. Ericsson, L. (1992) A morphometric and biomechanic comparison of titanium implants inserted in rabbit cortical and cancellous bone. International Journal of Oral & Maxillofacial Implants 7 : 62 71.
26. Stefani, C.M., Nogueira Filho, G.R., Sallum, E.A. Nociti, F.H. (2002) Influence of nicotine administration on different implant surfaces: a histometric study in rabbits. Journal of Periodontology 73 : 206 212.
27. Syversen, U., Nordsletten, L., Falch, J.A., Madsen, J.E., Nilsen, O.G. Waldum, H.L. (1999) Effect of lifelong nicotine inhalation on bone mass and mechanical properties in female rat femurs. Calcified Tissue International 65 : 246 249.
28. Ueng, S.W., Lee, M.Y., Li, A.F., Lin, S.S., Tai, C.L. Shih, C.H. (1997) Effect of intermittent cigarette smoke inhalation on tibial lengthening: experimental study on rabbits. The Journal of Trauma 42 : 231 8.
29. Weyant, R.J. (1994) Characteristics associated with the loss and peri-implant tissue health of endosseous dental implants. International Journal of Oral & Maxillofacial Implants 9 : 95 102.
30. Wing, K.J., Fisher, C.G., O'Connell, J.X. Wing, P.C. (2000) Stopping nicotine exposure before surgery. The effect on spinal fusion in a rabbit model. Spine 25 : 30 34.