CIZ gene rearrangements in acute leukemia: Report of a diagnostic FISH assay and clinical features of nine patients [13]

Leukemia

Volumn 19, Issue 9, 2005, Pages 1696-1699

  La Starza, R ^a   Aventin, A ^b   Crescenzi, B ^a   Gorello, P ^a   Specchia, G ^c   Cuneo, A ^d   Angioni, A ^e   Bilhou Nabera, C ^f   Boque C ^g   Foa R ^h   Uyttebroeck, A ⁱ   Talmant, P ^j   Cimino, G ^h   Martelli, M F ^a   Marynen, P ^k   Mecucci, C ^a   Hagemeijer, A ^k  

^a UNIVERSITY OF PERUGIA   (Italy)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^c UNIVERSITY OF FOGGIA   (Italy)

^d UNIVERSITY OF FERRARA   (Italy)

^e BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^f HAUT LÉVÊQUE HOSPITAL   (France)

^g CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^h SAPIENZA UNIVERSITY OF ROME   (Italy)

ⁱ Department of Paediatric Hematology ^*  (Belgium)

^j HÔTEL DIEU   (France)

^k DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

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Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BCR ABL PROTEIN; CD19 ANTIGEN; CD33 ANTIGEN; GENE PRODUCT; MICROSOMAL AMINOPEPTIDASE; PROTEIN CIZ; TRANSCRIPTION FACTOR E2A; UNCLASSIFIED DRUG; TRANSACTIVATOR PROTEIN; ZNF384 PROTEIN, HUMAN;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ANTIGEN EXPRESSION; BELGIUM; BONE MARROW TRANSPLANTATION; CHILD; CHROMOSOME 12P; CHROMOSOME 19P; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FRANCE; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETIC MARKER; HUMAN; INTERPHASE; KARYOTYPE; LETTER; MALE; METAPHASE; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; SPAIN; TRISOMY 13; Y CHROMOSOME; ACUTE LYMPHOCYTIC LEUKEMIA; CASE REPORT; GENE ORDER; GENETICS; METHODOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; GENE ORDER; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; TRANS-ACTIVATORS;

EID: 26944442820     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2403842     Document Type: Letter

References (4)

1. Martini A, La Starza R, Janssen H, Bilhou-Nabera C, Corveleyn A, Somers R et al. Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia. Cancer Res 2002; 62: 5408-5412.
2. Zucman J, Delattre O, Desmaze C, Plougastel B, Joubert I, Melot T et al. Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoint. Genes Chromosomes Cancer 1992; 5: 271-277.
3. Krance RA, Raimondi SC, Dubowy R, Estrada J, Borowitz M, Behm F et al. T(12;17)(p13;q21) in early pre-13 acute lymphoid leukemia. Leukemia 1992; 6: 251-255.
4. Cimino G, Elia L, Mancini M, Annino L, Anaclerico B, Fazi P, et al., for the GIMEMA Group. Clinico-biologic features and treatment outcome of adult pro-B-ALL patients enrolled in the GIMEMA 0496 study: Absence of the ALL1/AF4 and of the BCR/ABL fusion genes correlates with a significantly better clinical outcome. Blood 2003; 102: 2014-2020.