Distinct M50 and M100 auditory gating deficits in schizophrenia

Psychophysiology

Volumn 42, Issue 4, 2005, Pages 417-427

  Hanlon, Faith M ^a,b,c,d   Miller, Gregory A ^d,e   Thoma, Robert J ^a,c,d   Irwin, Jessica ^a   Jones, Aaron ^a   Moses, Sandra N ^h   Huang, Mingxiong ^f,g   Weisend, Michael P ^a,c   Paulson, Kim M ^a   Edgar, J Christopher ^e   Adler, Lawrence E ^h,i   Cañive, Jose M ^a,d,j  

^a NEW MEXICO VA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c MIND RESEARCH NETWORK   (United States)

^d UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^f ROTMAN RESEARCH INSTITUTE   (Canada)

^g VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^h VETERANS AFFAIRS MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF COLORADO   (United States)

^j VA Medical Center   (United States)

more..

Author keywords

Auditory sensory gating; M100; M50; Magnetoencephalography; Schizophrenia

Indexed keywords

ADULT; ARTICLE; CHANNEL GATING; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DIPOLE; FEMALE; HUMAN; LEFT HEMISPHERE; MAGNETOENCEPHALOGRAPHY; MALE; PERCEPTION DEAFNESS; PRIORITY JOURNAL; REGRESSION ANALYSIS; RIGHT HEMISPHERE; SCHIZOPHRENIA; CLINICAL TRIAL; HEARING; HEMISPHERIC DOMINANCE; IMAGE PROCESSING; PHYSIOLOGY; PSYCHOLOGY;

ADULT; AUDITORY PERCEPTION; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETOENCEPHALOGRAPHY; MALE; SCHIZOPHRENIC PSYCHOLOGY;

EID: 26944440572     PISSN: 00485772     EISSN: 14698986     Source Type: Journal    
DOI: 10.1111/j.1469-8986.2005.00299.x     Document Type: Article

References (66)

1. Adler, L. E., Cawthra, E. M., Donovan, K. A., Harris, J. G., Nagamoto, H. T., Olincy, A., et al. (2005). Improved P50 auditory gating with ondansetron in medicated schizophrenia patients. American Journal of Psychiatry, 162, 386-388.
2. Adler, L. E., Gerhardt, G. A., Franks, R., Baker, N., Nagamoto, H., Drebing, C., et al. (1990). Sensory physiology and catecholamines in schizophrenia and mania. Psychiatry Research, 31, 297-309.
3. Adler, L. E., Olincy, A., Cawthra, E. M., McRae, K. A., Harris, J. G., Nagamoto, H. T., et al. (2004). Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients. American Journal of Psychiatry, 161, 1822-1828.
4. Adler, L. E., Pachtman, E., Franks, R. D., Pecevich, M., Waldo, M. C., & Freedman, R. (1982). Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia. Biological Psychiatry, 17, 639-654.
5. Arciniegas, D., Olincy, A., Topkoff, J., McRae, K., Cawthra, E., Filley, C. M., et al. (2000). Impaired auditory gating and P50 non-suppression following traumatic brain injury. Journal of Neuropsychiatry Clinical Neuroscience, 12, 77-85.
6. Arnfred, S. M., Chen, A. C. N., Glenthoj, B. Y., & Hemmingsen, R. P. (2003). Normal P50 gating in unmedicated schizophrenia outpatients. American Journal of Psychiatry, 160, 2236-2238.
7. Blumenfeld, L. D., & Clementz, B. A. (1999). Hemispheric differences on auditory evoked response suppression in schizophrenia. NeuroReport, 10, 2587-2591.
8. Boutros, N. N., Belger, A., Campbell, D., D'Souza, C., & Krystal, J. (1999). Comparison of four components of sensory gating in schizophrenia and normal subjects: A preliminary report. Psychiatry Research, 88, 119-130.
9. Boutros, N. N., Korzyukov, O., Jansen, B., Feingold, A., & Bell, M. (2004). Sensory gating deficits during the mid-latency phase of information processing in medicated schizophrenia patients. Psychiatry Research, 126, 203-215.
10. Boutros, N. N., Overall, J., & Zouridakis, G. (1991). Test-retest reliability of the P50 mid-latency auditory evoked response. Psychiatry Research, 39, 181-192.
11. Boutros, N. N., Zouridakis, G., & Overall, J. (1991). Replication and extension of P50 findings in schizophrenia. Clinical Electroencephalography, 22, 40-45.
12. Bramon, E., Rabe-Hesketh, S., Sham, P., Murray, R. M., & Frangou, S. (2004). Meta-analysis of the P300 and P50 waveforms in schizophrenia. Schizophrenia Research, 70, 315-329.
13. Cardenas, V. A., Gerson, J., & Fein, G. (1993). The reliability of P50 suppression as measured by the conditioning/testing ratio is vastly improved by dipole modeling. Biological Psychiatry, 33, 335-344.
14. Chao, L. L., & Knight, R. T. (1998). Contribution of human prefrontal cortex to delay performance. Journal of Cognitive Neuroscience, 10, 167-177.
15. Clementz, B. A., & Blumenfeld, L. D. (2001). Multichannel electroencephalographic assessment of auditory evoked response suppression in schizophrenia. Experimental Brain Research, 139, 377-390.
16. Clementz, B. A., Blumenfeld, L. D., & Cobb, S. (1997). The gamma band response may account for poor P50 suppression in schizophrenia. NeuroReport, 8, 3889-3893.
17. Clementz, B. A., Dzau, J. R., Blumenfeld, L. D., Matthews, S., & Kissler, J. (2003). Ear of stimulation determines schizophrenia-normal brain activity differences in an auditory paired-stimuli paradigm. European Journal of Neuroscience, 18, 2853-2858.
18. Clementz, B. A., Geyer, M. A., & Braff, D. L. (1997). P50 suppression among schizophrenia and normal comparison subjects: A methodological analysis. Biological Psychiatry, 41, 1035-1044.
19. Deldin, P. J., Miller, G. A., & Gergen, J. A. (1991). Partial evidence for P50 suppression in schizophrenia. Poster session presented at the annual meeting of the Society for Research in Psychopathology, Boston.
20. Edgar, J. C., Huang, M. X., Weisend, M. P., Sherwood, A., Miller, G. A., Adler, L. E., et al. (2003). Interpreting abnormality: An EEG and MEG study of P50 and the auditory paired-stimulus paradigm. Biological Psychology, 65, 1-20.
21. Fein, G., Biggins, C., & MacKay, S. (1996). Cocaine abusers have reduced auditory P50 amplitude and suppression compared to both normal controls and alcoholics. Biological Psychiatry, 39, 955-965.
22. First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (1996). Structured Clinical Interview for DSM-IV Axis I Disorders (SCID), Clinician Version. Washington, DC: American Psychiatric Press.
23. Franks, R. D., Adler, L. E., Waldo, M. C., Alpert, J., & Freedman, R. (1983). Neurophysiological studies of sensory gating in mania: Comparison with schizophrenia. Biological Psychiatry, 18, 989-1005.
24. Freedman, R., Adler, L. E., Gerhardt, G. A., Waldo, M., Baker, N., Rose, G. M., et al. (1987). Neurobiological studies of sensory gating in schizophrenia. Schizophrenia Bulletin, 13, 669-678.
25. Freedman, R., Adler, L. E., & Leonard, S. (1999). Alternative phenotypes for the complex genetics of schizophrenia. Biological Psychiatry, 45, 551-558.
26. Freedman, R., Adler, L. E., Waldo, M. C., Pachtman, E., & Franks, R. D. (1983). Neurophysiological evidence for a defect in inhibitory pathways in schizophrenia: Comparison of medicated and drug-free patients. Biological Psychiatry, 18, 537-551.
27. Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., et al. (1997). Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proceedings of the National Academy of Sciences of the United States of America, 94, 587-592.
28. Friston, K. J. (1999). Schizophrenia and the disconnection hypothesis. Acta Psychiatrica Scandinavica Supplementum, 395, 68-79.
29. Hajek, M., Huonker, R., Boehle, C., Volz, H. P., Nowak, H., & Sauer, H. (1997). Abnormalities of auditory evoked magnetic fields and structural changes in the left hemisphere of male schizophrenics-A magnetoencephalographic- magnetic resonance imaging study. Biological Psychiatry, 42, 609-616.
30. Hsieh, M. H., Liu, K., Liu, S. K., Chiu, M. J., Hwu, H. G., & Chen, A. C. N. (2004). Memory impairment and auditory evoked potential gating deficit in schizophrenia. Psychiatry Research: Neuroimaging, 130, 161-169.
31. Huang, M. X., Edgar, J. C., Thoma, R. J., Hanlon, F. M., Moses, S. N., Lee, R. R., et al. (2003). Predicting EEG responses using MEG sources in superior temporal gyrus reveals source asynchrony in patients with schizophrenia. Clinical Neurophysiology, 114, 835-850.
32. Huotilainen, M., Winkler, I., Alho, K., Escera, C., Virtanen, J., Ilmoniemi, R. J., et al. (1998). Combined mapping of human auditory EEG and MEG responses. Electroencephalography and Clinical Neurophysiology, 108, 370-379.
33. Jerger, K., Biggins, C., & Fein, G. (1992). P50 suppression is not affected by attentional manipulations. Biological Psychiatry, 31, 365-377.
34. Jessen, F., Kucharski, C., Fries, T., Papassotiropoulos, A., Hoenig, K., Maier, W., et al. (2001). Sensory gating deficit expressed by a disturbed suppression of the P50 event-related potential in patients with Alzheimer's disease. American Journal of Psychiatry, 158, 1319-1321.
35. Jin, Y., Potkin, S. G., Patterson, J. V., Sandman, C. A., Hetrick, W. P., & Bunney, W. E., Jr. (1997). Effects of P50 temporal variability on sensory gating in schizophrenia. Psychiatry Research, 70, 71-81.
36. Judd, L. L., McAdams, L., Budnick, B., & Braff, D. L. (1992). Sensory gating deficits in schizophrenia: New results. American Journal of Psychiatry, 149, 488-493.
37. Kasai, K., Shenton, M. E., Salisbury, D. F., Hirayasu, Y., Onitsuka, T., Spencer, M. H., et al. (2003). Progressive decrease of left heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia. Archives of General Psychiatry, 60, 766-775.
38. Kathmann, N., & Engel, R. R. (1990). Sensory gating in normals and schizophrenics: A failure to find strong P50 suppression in normals. Biological Psychiatry, 27, 1216-1226.
39. Kisley, M. A., Noecker, T. L., & Guinther, P. M. (2004). Comparison of sensory gating to mismatch negativity and self-reported perceptual phenomena in healthy adults. Psychophysiology, 41, 604-612.
40. Knight, R. T., Scabini, D., & Woods, D. L. (1989). Prefrontal cortex gating of auditory transmission in humans. Brain Research, 504, 338-342.
41. Leahy, R. M., Mosher, J. C., Spencer, M. E., Huang, M. X., & Lewine, J. D. (1998). A study of dipole localization accuracy for MEG and EEG using a human skull phantom. Electroencephalography and Clinical Neurophysiology, 107, 159-173.
42. Leonard, S., Gault, J., Hopkins, J., Logel, J., Vianzon, R., Short, M., et al. (2002). Association of promoter variants in the alpha 7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Archives of General Psychiatry, 59, 1085-1096.
43. Lewine, J. D., & Orrison, W. W., Jr. (1995). Magnetoencephalography and magnetic source imaging. In W. W. Orrison Jr., J. D. Lewine, J. A. Sanders, & M. F. Hartshorne (Eds.), Functional brain imaging (pp. 369-471). St. Louis: Mosby.
44. Light, G. A., Geyer, M. A., Clementz, B. A., Cadenhead, K. S., & Braff, D. L. (2000). Normal P50 suppression in schizophrenia patients treated with atypical antipsychotic medications. American Journal of Psychiatry, 157, 767-771.
45. Mäkelä, J. P., Hämäläinen, M., Hari, R., & McEvoy, L. (1994). Whole-head mapping of middle-latency auditory evoked magnetic fields. Electroencephalography and Clinical Neurophysiology, 92, 414-421.
46. McCarley, R. W., Salisbury, D. F., Hirayasu, Y., Yurgelun-Todd, D. A., Tohen, M., Zarate, C., et al. (2002). Association between smaller left posterior superior temporal gyrus volume on magnetic resonance imaging and smaller left temporal P300 amplitude in first-episode schizophrenia. Archives of General Psychiatry, 59, 321-331.
47. McCarley, R. W., Shenton, M. E., O'Donnell, B. F., Faux, S. F., Kikinis, R., Nestor, P. G., et al. (1993). Auditory P300 abnormalities and left posterior superior temporal gyrus volume reduction in schizophrenia. Archives of General Psychiatry, 50, 190-197.
48. Miller, G. A., & Chapman, J. P. (2001). Misunderstanding analysis of covariance. Journal of Abnormal Psychology, 110, 40-48.
49. Näätänen, R., & Picton, T. (1987). The N1 wave of the human electric and magnetic response to sound: A review and an analysis of the component structure. Psychophysiology, 24, 375-425.
50. Nagamoto, H. T., Adler, L. E., Hea, R. A., Griffith, J. M., McRae, K. A., & Freedman, R. (1996). Gating of auditory P50 in schizophrenics: Unique effects of clozapine. Biological Psychiatry, 40, 181-188.
51. Nagamoto, H. T., Adler, L. E., Waldo, M. C., & Freedman, R. (1989). Sensory gating in schizophrenics and normal controls: Effects of changing stimulation interval. Biological Psychiatry, 25, 549-561.
52. Neylan, T. C., Fletcher, D. J., Lenoci, M., McCallin, K., Weiss, D. S., Schoenfeld, F. B., et al. (1999). Sensory gating in chronic posttraumatic stress disorder: Reduced auditory P50 suppression in combat veterans. Biological Psychiatry, 46, 1656-1664.
53. Onitsuka, T., Ninomiya, H., Sato, E., Yamamoto, T., & Tashiro, N. (2000). The effect of interstimulus intervals and between-block rests on the auditory evoked potential and magnetic field: Is the auditory P50 in humans an overlapping potential? Clinical Neurophysiology, 111, 237-245.
54. Pearlson, G. D., Barta, P. E., Powers, R. E., Menon, R. R., Richards, S. S., Aylward, E. H., et al. (1997). Ziskind-Somerfeld Research Award 1996. Medial and superior temporal gyral volumes and cerbral asymmetry in schizophrenia versus bipolar disorder. Biological Psychiatry, 41, 1-14.
55. Pelizzone, M., Hari, R., Mäkelä, J. P., Huttunen, J., Ahlfors, S., & Hämäläinen, M. (1987). Cortical origin of middle-latency auditory evoked responses in man. Neuroscience Letters, 82, 303-307.
56. Reite, M., Teale, P., Goldstein, L., Whalen, J., & Linnville, S. (1989). Late auditory magnetic sources may differ in the left hemisphere of schizophrenia patients. A preliminary report. Archives of General Psychiatry, 46, 565-572.
57. Reite, M., Teale, P., Zimmerman, J., Davis, K., & Whalen, J. (1988). Source location of a 50 msec latency auditory evoked field component. Electroencephalography and Clinical Neurophysiology, 70, 490-498.
58. Sarvas, J. (1987). Basic mathematical and electromagnetic concepts of the bio-magnetic inverse problem. Physics in Medicine & Biology, 32, 11-22.
59. Smith, D. A., Boutros, N. N., & Schwarzkopf, S. B. (1994). Reliability of P50 auditory event-related potential indices of sensory gating. Psychophysiology, 31, 495-502.
60. Teale, P., Reite, M., Rojas, D. C., Sheeder, J., & Arciniegas, D. (2000). Fine structure of the auditory M100 in schizophrenia and schizoaffective disorder. Biological Psychiatry, 48, 1109-1112.
61. Teale, P., Sheeder, J., Rojas, D. C., Walker, J., & Reite, M. (1998). Sequential source of the M100 exhibits inter-hemispheric asymmetry. NeuroReport, 9, 2647-2652.
62. Thoma, R. J., Hanlon, F. M., Moses, S. N., Edgar, J. C., Huang, M. X., Weisend, M. P., et al. (2003). Lateralization of auditory sensory gating and neuropsychological dysfunction in schizophrenia. American Journal of Psychiatry, 160, 1595-1605.
63. Thoma, R. J., Hanlon, F. M., Moses, S. N., Ricker, D., Huang, M. X., Edgar, C., et al. (2005). M50 sensory gating predicts negative symptoms in schizophrenia. Schizophrenia Research, 73, 311-318.
64. Waldo, M. C., Adler, L. E., & Freedman, R. (1988). Defects in auditory sensory gating and their apparent compensation in relatives of schizophrenics. Schizophrenia Research, 1, 19-24.
65. Yee, C. M., Nuechterlein, K. H., Morris, S. E., & White, P. M. (1998). P50 suppression in recent-onset schizophrenia: Clinical correlates and risperidone effects. Journal of Abnormal Psychology, 107, 691-698.
66. Yoshiura, T., Ueno, S., Iramina, K., & Masuda, K. (1995). Source localization of middle latency auditory evoked magnetic fields. Brain Research, 703, 139-144.