Effect of pimobendan on cardiopulmonary baroreflex control of sympathetic nerve activity in healthy young men

Autonomic Neuroscience: Basic and Clinical

Volumn 122, Issue 1-2, 2005, Pages 100-106

  Maruyama, Michiro ^a   Takamura, Masayuki ^a   Takata, Shigeo ^a   Murai, Hisayoshi ^a   Usui, Soichiro ^a   Furusho, Hiroshi ^a   Sakagami, Satoru ^a   Yuasa, Toyoshi ^b   Shimakura, Atsuhiro ^c   Kaneko, Shuichi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b ISHIKAWA PREFECTURAL CENTRAL HOSPITAL   (Japan)

^c Toyama Teishin Hospital   (Japan)

Author keywords

Cardiopulmonary baroreceptor; Muscle sympathetic nerve activity; Pimobendan

Indexed keywords

PIMOBENDAN;

ADULT; ARTERIAL PRESSURE; ARTICLE; CARDIOPULMONARY HEMODYNAMICS; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; ELECTROCARDIOGRAM; HAND GRIP; HEART INDEX; HEART OUTPUT; HUMAN; LOWER BODY NEGATIVE PRESSURE; MALE; NERVE CONDUCTION; NORMAL HUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYMPATHETIC NERVE; SYMPATHETIC TONE;

ADULT; BAROREFLEX; BLOOD PRESSURE; CARDIOTONIC AGENTS; HEART RATE; HUMANS; MALE; MYOCARDIAL CONTRACTION; PYRIDAZINES; SYMPATHETIC NERVOUS SYSTEM;

EID: 26944431580     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2005.08.008     Document Type: Article

References (29)

1. W. Delius, K.-E. Hagbarth, A. Hongell, and B.G. Wallin General characteristics of sympathetic activity in human muscle nerves Acta Physiol. Scand. 84 1972 65 81
2. M.E. Dibner-Dunlap, M.L. Smith, T. Kinugawa, and M.D. Thames Enalaprilat augments arterial and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with heart failure J. Am. Coll. Cardiol. 27 1996 358 364
3. D.E. Donald, and J.T. Shepherd Reflexes from the heart and lungs: physiological curiosities or important regulatory mechanisms Cardiovasc. Res. 12 1978 449 469
4. D.W. Ferguson, M.D. Thames, and A.L. Mark Effects of propranolol on reflex vascular responses to orthostatic stress in humans: role of ventricular baroreceptors Circulation 67 1983 802 807
5. D.W. Ferguson, W.J. Berg, J.S. Sanders, P.J. Roach, J.S. Kempf, and M.G. Kienzle Sympathoinhibitory responses to digitalis glycosides in heart failure patients: direct evidence from sympathetic neural recordings Circulation 80 1989 65 77
6. D.W. Ferguson, W.J. Berg, P.J. Roach, R.M. Oren, A.L. Mark, and J.S. Kempf Effects of heart failure on baroreflex control of sympathetic neural activity Am. J. Cardiol. 69 1992 523 531
7. J.S. Floras Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure J. Am. Coll. Cardiol. 22 Suppl. A 1993 72A 84A
8. A.C. Guyton, C.E. Jones, and T.G. Coleman Indicator-dilution methods for determining cardiac output A.C. Guyton C.E. Jones T.G. Coleman Circulatory Physiology: Cardiac Output and its Regulation 1973 W.B. Saunders Company Philadelphia 40 80
9. F. Hagemeijer Calcium sensitization with pimobendan: pharmacology, haemodynamic improvement, and sudden death in patients with chronic congestive heart failure Eur. Heart J. 14 1993 551 566
10. P.J. Lacolley, B.M. Pannier, M.A. Slama, J.L. Cuche, A.P.G. Hoeks, S. Laurent, G.M. London, and M.E. Safar Carotid arterial haemodynamics after mild degrees of lower-body negative pressure in man Clin. Sci. 83 1992 535 540
11. D.T. Mason, and E. Braunwald A simplified plethysmographic system for the measurement of systemic arterial pressure and peripheral blood flow Am. Heart J. 64 1962 796 804
12. P.A. Modesti, G. Polidori, I. Bertolozzi, S. Vanni, and I. Cecioni Impairment of cardiopulmonary receptor sensitivity in the early phase of heart failure Heart 90 2004 30 36
13. P.K. Mohanty, J.A. Arrowood, K.A. Ellenbogen, and M.D. Thames Neurohumoral and hemodynamic effects of lower body negative pressure in patients with congestive heart failure Am. Heart J. 118 1989 78 85
14. Y. Nagata Flecainide augments muscle sympathetic nerve activity in humans Circ. J. 66 2002 377 381
15. B. Öberg, and P. Thorén Studies on left ventricular receptors, signalling in non-medullated vagal afferents Acta Physiol. Scand. 85 1972 145 163
16. B. Pannier, M.A. Slama, G.M. London, M.E. Safar, and J.L. Cuche Carotid arterial hemodynamics in response to LBNP in normal subjects: methodological aspects J. Appl. Physiol. 79 1995 1546 1555
17. P. Ponikowski, D.P. Francis, M.F. Piepoli, L.C. Davies, T.P. Chua, C.H. Davos, V. Florea, W. Banasiak, P.A. Poole-Wilson, A.J.S Coats, and S.D. Anker Enhanced ventilatory response to exercise in patients with chronic heart failure and preserved exercise tolerance: marker of abnormal cardiorespiratory reflex control and predictor of poor prognosis Circulation 103 2001 967 972
18. U. Scherrer, S.F. Vissing, and R.G. Victor Effects of lower-body negative pressure on sympathetic nerve responses to static exercise in humans: microneurographic evidence against cardiac baroreflex modulation of the exercise pressor reflex Circulation 78 1988 49 59
19. H. Senzaki, T. Isoda, N. Paolocci, U. Ekelund, J.M. Hare, and D.A. Kass Improved mechanoenergetics and cardiac rest and reserve function of in vivo failing heart by calcium sensitizer EMD-57033 Circulation 101 2000 1040 1048
20. S. Sundberg, J. Lilleberg, M.S. Nieminen, and L. Lehtonen Hemodynamic and neurohumoral effects of levosimendan, a new calcium sensitizer, at rest and during exercise in healthy men Am. J. Cardiol. 75 1995 1061 1066
21. G. Sundlof, and B.G. Wallin Effect of lower body negative pressure on human muscle nerve sympathetic activity J. Physiol. 278 1978 525 532
22. M.D. Thames, D.E. Donald, and J.T. Shepherd Behavior of cardiac receptors with nonmyelinated vagal afferents during spontaneous respiration in cats Circ. Res. 41 1977 694 701
23. J.A. Taylor, J.R. Halliwill, T.E. Brown, J. Hayano, and D.L. Eckberg 'Non-hypotensive' hypovolaemia reduces ascending aortic dimensions in humans J. Physiol. 493 1995 289 298
24. The Pimobendan-Enalapril Study Group W.J. Remme Long-term efficacy and safety of pimobendan in moderate heart failure: a double-blind parallel 6-month comparison with enalapril Eur. Heart J. 15 1994 947 956
25. The Pimobendan in Congestive Heart Failure (PICO) Investigators Effect of pimobendan on exercise capacity in patients with heart failure: main results from the Pimobendan in Congestive Heart Failure (PICO) trial Heart 76 1996 223 231
26. The Pimobendan Multicenter Research Group S.H. Kubo Beneficial effects of pimobendan on exercise tolerance and quality of life in patients with heart failure: results of a multicenter trial Circulation 85 1992 942 949
27. The Pimobendan Multicenter Research Group T.S. Rector, and J.N. Cohn Assessment of patient outcome with the Minnesota living with heart failure questionnaire: relatively and validity during a randomized, double-blind, placebo-controlled trial of pimobendan Am. Heart J. 124 1992 1017 1025
28. P.N. Thorén Characteristics of left ventricular receptors with nonmedullated vagal afferents in cats Circ. Res. 40 1977 415 421
29. J.C. van Meel, and W. Diederen Hemodynamic profile of the cardiotonic agent pimobendan J. Cardiovasc. Pharmacol. 14 Suppl. 2 1989 S1 S6