Folate system correlations in DNA microarray data

BMC Cancer

Volumn 5, Issue , 2005, Pages

  Radivoyevitch, Tomas ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FOLIC ACID; PURINE; THYMIDINE PHOSPHATE; MESSENGER RNA; PURINE DERIVATIVE; THYMIDYLATE SYNTHASE;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; DNA DAMAGE; DNA MICROARRAY; GENE EXPRESSION SYSTEM; GROWTH INHIBITION; HUMAN; IONIZING RADIATION; MATHEMATICAL MODEL; PREDICTION; PURINE SYNTHESIS; RADIATION EXPOSURE; STEADY STATE; ACUTE LYMPHOBLASTIC LEUKEMIA; ALGORITHM; BIOLOGICAL MODEL; BIOLOGY; CHEMICAL MODEL; DNA REPAIR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; KINETICS; METABOLISM; METHODOLOGY; STATISTICAL ANALYSIS; THEORETICAL MODEL; TIME;

ALGORITHMS; CELL PROLIFERATION; COMPUTATIONAL BIOLOGY; DATA INTERPRETATION, STATISTICAL; DNA DAMAGE; DNA REPAIR; FOLIC ACID; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KINETICS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, THEORETICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PURINES; RADIATION, IONIZING; RNA, MESSENGER; THYMIDYLATE SYNTHASE; TIME FACTORS;

EID: 26844577193     PISSN: 14712407     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-5-95     Document Type: Article

References (23)

1. Morrison PF, Allegra CJ: Folate cycle kinetics in human breast cancer cells. J Biol Chem 1989, 264(18):10552-10566.
2. Curtin NJ, Hughes AN: Pemetrexed disodium, a novel antifolate with multiple targets. Lancet Oncol 2001, 2(5):298-306.
3. Shih C, Habeck LL, Mendelsohn LG, Chen VJ, Schultz RM: Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA). Adv Enzyme Regul 1998, 38:135-152.
4. Yin MB, Guimaraes MA, Zhang ZG, Arredondo MA, Rustum YM: Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor. Cancer Res 1992, 52(21):5900-5905.
5. Spiegelman S, Sawyer R, Nayak R, Ritzi E, Stolfi R, Martin D: Improving the anti-tumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation. Proc Natl Acad Sci USA 1980, 77(8):4966-4970.
6. Ross ME, Zhou X, Song G, Shurtleff SA, Girtman K, Williams WK, Liu HC, Mahfouz R, Raimondi SC, Lenny N, Patel A, Downing JR: Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. Blood 2003, 102(8):2951-2959.
7. Yeoh EJ, Ross ME, Shurtleff SA, Williams WK, Patel D, Mahfouz R, Behm FG, Raimondi SC, Relling MV, Patel A, Cheng C, Campana D, Wilkins D, Zhou X, Li J, Liu H, Pui CH, Evans WE, Naeve C, Wong L, Downing JR: Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell 2002, 1(2):133-143.
8. Jen KY, Cheung VG: Transcriptional response of lymphoblastoid cells to ionizing radiation. Genome Res 2003, 13(9):2092-2100.
9. Zheng PZ, Wang KK, Zhang QY, Huang QH, Du YZ, Zhang QH, Xiao DK, Shen SH, Imbeaud S, Eveno E, Zhao CJ, Chen YL, Fan HY, Waxman S, Auffray C, Jin G, Chen SJ, Chen Z, Zhang J: Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proc Natl Acad Sci U S A 2005.
10. Oppenheim AV, Willsky AS, Young IT: Signals and Systems. Prentice Hall, Englewood Cliffs, NJ; 1983:763-763.
11. Ihaka R, Gentleman R: R:a language for data analysis and graphics. Journal of Computational and graphical statistics 1996, 5:299-314.
12. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J: Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004, 5(10):R80.
13. Radivoyevitch T: SBMLR. [http://www.bioconductor.org/repository/devel/package/html/SBMLR.html].
14. Radivoyevitch T: Radivoyevitch Lab. [http://epbiradivot.cwru.edu/].
15. Systems Biology Markup Language [http://sbml.org]
16. Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Gor V, Goryanin II, Hedley WJ, Hodgman TC, Hofmeyr JH, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer U, Le Novere N, Loew LM, Lucio D, Mendes P, Minch E, Mjolsness ED, Nakayama Y, Nelson MR, Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi K, Tomita M, Wagner J, Wang J: The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics 2003, 19(4):524-531.
17. Finney A, Hucka M: Systems biology markup language: Level 2 and beyond. Biochem Soc Trans 2003, 31(Pt 6):1472-1473.
18. Dervieux T, Brenner TL, Hon YY, Zhou Y, Hancock ML, Sandlund JT, Rivera GK, Ribeiro RC, Boyett JM, Pui CH, Relling MV, Evans WE: De novo purine synthesis inhibition and antileukemic effects of mercaptopurine alone or in combination with methotrexate in vivo. Blood 2002, 100(4):1240-1247.
19. Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U: Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet 2004, 36(2):147-150.
20. Tanaka H, Arakawa H, Yamaguchi T, Shiraishi K, Fukuda S, Matsui K, Takei Y, Nakamura Y: A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage. Nature 2000, 404(6773):42-49.
21. Kuo ML, Kinsella TJ: Expression of ribonucleotide reductase after ionizing radiation in human cervical carcinoma cells. Cancer Res 1998, 58(10):2245-2252.
22. Kuo ML, Hwang HS, Sosnay PR, Kunugi KA, Kinsella TJ: Overexpression of the R2 subunit of ribonucleotide reductase in human nasopharyngeal cancer cells reduces radiosensitivity. Cancer J 2003, 9(4):277-285.
23. Tai N, Schmitz JC, Liu J, Lin X, Bailly M, Chen TM, Chu E: Translational autoregulation of thymidylate synthase and dihydrofolate reductase. Front Biosci 2004, 9:2521-2526.