-
2
-
-
0019199109
-
Metabolism of acrylonitrile to cyanide: In vitro studies
-
Abreu, M. E., and Ahmed, A. E. (1980). Metabolism of acrylonitrile to cyanide: In vitro studies. Drug. Metab. Dispos. 8, 376-379.
-
(1980)
Drug. Metab. Dispos.
, vol.8
, pp. 376-379
-
-
Abreu, M.E.1
Ahmed, A.E.2
-
3
-
-
0026480664
-
Pulmonary toxicity of acrylonitrile: Covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung
-
Ahmed, A. E., Abdel-Aziz, A. H., Abdel-Rahman, S. Z., Haque, A. K., Nouraldeen, A. M., and Shouman, S. A. (1992). Pulmonary toxicity of acrylonitrile: Covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung. Toxicology 76, 1-4.
-
(1992)
Toxicology
, vol.76
, pp. 1-4
-
-
Ahmed, A.E.1
Abdel-Aziz, A.H.2
Abdel-Rahman, S.Z.3
Haque, A.K.4
Nouraldeen, A.M.5
Shouman, S.A.6
-
4
-
-
0019996893
-
Distribution and covalent interaction of acrylonitrile in the rat
-
Ahmed, A. E., Farooqui, M. Y. H., Upreti, R. K., and El-Shabrawy, O. (1982). Distribution and covalent interaction of acrylonitrile in the rat. Toxicology 23, 159-175.
-
(1982)
Toxicology
, vol.23
, pp. 159-175
-
-
Ahmed, A.E.1
Farooqui, M.Y.H.2
Upreti, R.K.3
El-Shabrawy, O.4
-
6
-
-
77957180437
-
Quantitative whole body autoradiographic disposition of glycol ether in mice: Effect of route of administration
-
Ahmed, A. E., Jacob, S., and Au, W. W. (1994). Quantitative whole body autoradiographic disposition of glycol ether in mice: Effect of route of administration. Fundam. Appl. Toxicol. 22, 266-276.
-
(1994)
Fundam. Appl. Toxicol.
, vol.22
, pp. 266-276
-
-
Ahmed, A.E.1
Jacob, S.2
Au, W.W.3
-
9
-
-
0019406020
-
Acrylonitrile: In vivo metabolism in rats and mice
-
Ahmed, A. E., and Patel, K. (1981). Acrylonitrile: In vivo metabolism in rats and mice. Drug Metab. Dispos. 9, 219-222.
-
(1981)
Drug Metab. Dispos.
, vol.9
, pp. 219-222
-
-
Ahmed, A.E.1
Patel, K.2
-
10
-
-
0000259380
-
Aliphatic nitriles: Metabolism and toxicity
-
(J. W. Bridges and L. F. Chasseaud, Eds.), Wiley, New York
-
Ahmed, A. E., and Trieff, N. M. (1983). Aliphatic nitriles: Metabolism and toxicity. In Progress in Drug Metabolism (J. W. Bridges and L. F. Chasseaud, Eds.), Vol. 7, pp. 229-294. Wiley, New York.
-
(1983)
Progress in Drug Metabolism
, vol.7
, pp. 229-294
-
-
Ahmed, A.E.1
Trieff, N.M.2
-
11
-
-
0028046087
-
Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats
-
Burka, L. T., Sanchez, I. M., Ahmed, A. E., and Ghanayem, B. I. (1994). Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats. Arch. Toxicol. 68, 611-618.
-
(1994)
Arch. Toxicol.
, vol.68
, pp. 611-618
-
-
Burka, L.T.1
Sanchez, I.M.2
Ahmed, A.E.3
Ghanayem, B.I.4
-
12
-
-
0011847759
-
Physical properties and biological activity
-
(A. Burger, Ed.), Ch. 9
-
Camarata, A., and Martin, A. N. (1970). Physical properties and biological activity. In Medicinal Chemistry (A. Burger, Ed.), Ch. 9, pp. 118-163.
-
(1970)
Medicinal Chemistry
, pp. 118-163
-
-
Camarata, A.1
Martin, A.N.2
-
13
-
-
0024596196
-
Disposition of methacrylonitrile in rats and distribution in blood components
-
Cavazos, R., Jr., Farooqui, M. Y. H., Day, W. W., Villarreal, M. I., and Massa, E. (1989). Disposition of methacrylonitrile in rats and distribution in blood components. J. Appl. Toxicol. 9, 53-57.
-
(1989)
J. Appl. Toxicol.
, vol.9
, pp. 53-57
-
-
Cavazos R., Jr.1
Farooqui, M.Y.H.2
Day, W.W.3
Villarreal, M.I.4
Massa, E.5
-
14
-
-
0024231108
-
Interaction of methacrylonitrile with glutathione
-
Day, W. W., Cavazos, R., Jr., and Farooqui, M. Y. H. (1988). Interaction of methacrylonitrile with glutathione. Res. Commun. Chem. Pathol. Pharmacol. 62, 267-278.
-
(1988)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.62
, pp. 267-278
-
-
Day, W.W.1
Cavazos R., Jr.2
Farooqui, M.Y.H.3
-
15
-
-
0019974167
-
Mortality among rubber workers. VI. Men with exposure to acrylonitrile
-
Delzell, E., and Monson, R. R. (1982). Mortality among rubber workers. VI. Men with exposure to acrylonitrile. J. Occup. Med. 24, 767-769.
-
(1982)
J. Occup. Med.
, vol.24
, pp. 767-769
-
-
Delzell, E.1
Monson, R.R.2
-
16
-
-
0002590216
-
Toxicology of acrylonitrile (vinyl cyanide). 1. A study of the acute toxicity
-
Dudley, H. C., and Neal, P. A. (1942). Toxicology of acrylonitrile (vinyl cyanide). 1. A study of the acute toxicity. J. Ind. Hyg. Toxicol. 24, 27-36.
-
(1942)
J. Ind. Hyg. Toxicol.
, vol.24
, pp. 27-36
-
-
Dudley, H.C.1
Neal, P.A.2
-
18
-
-
0025444201
-
Metabolism of methacrylonitrile to cyanide: In vitro studies
-
Farooqui, M. Y. H., Diaz, R. G., and Cavazos, R., Jr. (1990). Metabolism of methacrylonitrile to cyanide: In vitro studies. J. Biochem. Toxicol. 5, 109-114.
-
(1990)
J. Biochem. Toxicol.
, vol.5
, pp. 109-114
-
-
Farooqui, M.Y.H.1
Diaz, R.G.2
Cavazos R., Jr.3
-
19
-
-
0026099218
-
Toxicology of methacrylonitrile
-
Farooqui, M. Y. H., and Mumtaz, M. M. (1991). Toxicology of methacrylonitrile. Toxicology 65, 239-250.
-
(1991)
Toxicology
, vol.65
, pp. 239-250
-
-
Farooqui, M.Y.H.1
Mumtaz, M.M.2
-
21
-
-
0020574194
-
Acrylonitrile-induced gastroin-testinal hemorrhage and the effects of metabolism modulation in rats
-
Ghanayem, B. I., and Ahmed, A. E. (1983). Acrylonitrile-induced gastroin-testinal hemorrhage and the effects of metabolism modulation in rats. Toxicol. Appl. Pharmacol. 68, 290-296.
-
(1983)
Toxicol. Appl. Pharmacol.
, vol.68
, pp. 290-296
-
-
Ghanayem, B.I.1
Ahmed, A.E.2
-
22
-
-
0011855052
-
-
Abstract 1304
-
Ghanayem, B. I., Demby, K. B., Merrill, T. E., and Burka, L. T. (1994). Toxicologist 14, Abstract 1304, p. 336.
-
(1994)
Toxicologist
, vol.14
, pp. 336
-
-
Ghanayem, B.I.1
Demby, K.B.2
Merrill, T.E.3
Burka, L.T.4
-
23
-
-
0026739479
-
Effects of dose, strain, and dosing vehicle on methacrylonitrile disposition in rats and identification of a novel-exhaled metabolite
-
Ghanayem, B. I., Sanchez, I. M., and Burka, L. T. (1992). Effects of dose, strain, and dosing vehicle on methacrylonitrile disposition in rats and identification of a novel-exhaled metabolite. Drug Metab. Dispos. 20, 643-652.
-
(1992)
Drug Metab. Dispos.
, vol.20
, pp. 643-652
-
-
Ghanayem, B.I.1
Sanchez, I.M.2
Burka, L.T.3
-
24
-
-
0019825946
-
In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids
-
Guengerich, F. P., Geiger, L. E., Hogy, L. L., and Wright, P. L. (1981). In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids. Cancer Res. 41, 4925-4933.
-
(1981)
Cancer Res.
, vol.41
, pp. 4925-4933
-
-
Guengerich, F.P.1
Geiger, L.E.2
Hogy, L.L.3
Wright, P.L.4
-
25
-
-
0028863077
-
Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione
-
Kedderis, G. L., Batra, R., and Turner, M. J. (1995). Conjugation of acrylonitrile and 2-cyanoethylene oxide with hepatic glutathione. Toxicol. Appl. Pharmacol. 135, 9-18.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.135
, pp. 9-18
-
-
Kedderis, G.L.1
Batra, R.2
Turner, M.J.3
-
26
-
-
0027258742
-
Dose dependent urinary excretion of acrylonitrile metabolites by rats and mice
-
Kedderis, G. L., Sumner, S. C. J., Held, S. D., Batra, R., Turner, M. J., Jr., Roberts, A. E., and Fennel, T. R. (1993). Dose dependent urinary excretion of acrylonitrile metabolites by rats and mice. Toxicol. Appl. Pharmacol. 120, 288-297.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.120
, pp. 288-297
-
-
Kedderis, G.L.1
Sumner, S.C.J.2
Held, S.D.3
Batra, R.4
Turner M.J., Jr.5
Roberts, A.E.6
Fennel, T.R.7
-
27
-
-
84920303808
-
Toxic effect of methacrylonitrile on the body of experimental animals after chronic exposure
-
Kurzalieve, S. A., and Zueve, A. N. (1988). Toxic effect of methacrylonitrile on the body of experimental animals after chronic exposure. Gig. Tr. Prof. Zabol (USSR) 4, 51-52.
-
(1988)
Gig. Tr. Prof. Zabol (USSR)
, vol.4
, pp. 51-52
-
-
Kurzalieve, S.A.1
Zueve, A.N.2
-
28
-
-
0017586264
-
Carcinogenicity bioassays on rats of acrylonitrile administered by inhalation and by ingestion
-
Maltoni, C., Ciliberti, A., and Maio, D. V. (1977). Carcinogenicity bioassays on rats of acrylonitrile administered by inhalation and by ingestion. Med. Lav. 68, 401-411.
-
(1977)
Med. Lav.
, vol.68
, pp. 401-411
-
-
Maltoni, C.1
Ciliberti, A.2
Maio, D.V.3
-
29
-
-
77957176597
-
The reactivities of selected acrylate esters toward glutathione and deoxyribonucleosides in vitro: Structure activity relationships
-
McCarthy, T. J., Hayes, E. P., Schwartz, C. S., and Witz, G. (1994). The reactivities of selected acrylate esters toward glutathione and deoxyribonucleosides in vitro: Structure activity relationships. Fundam. Appl. Toxicol. 22, 543-548.
-
(1994)
Fundam. Appl. Toxicol.
, vol.22
, pp. 543-548
-
-
McCarthy, T.J.1
Hayes, E.P.2
Schwartz, C.S.3
Witz, G.4
-
30
-
-
0000068813
-
Comparative toxicity of methacrylonitrile and acrylonitrile
-
McOmie, W. A. (1949). Comparative toxicity of methacrylonitrile and acrylonitrile. J. Ind. Hyg. Toxicol. 31, 113-121.
-
(1949)
J. Ind. Hyg. Toxicol.
, vol.31
, pp. 113-121
-
-
McOmie, W.A.1
-
31
-
-
0004234130
-
-
Allyn & Bacon, Boston
-
Morrison, R. T., and Boyd, R. N. (1963). Organic Chemistry, pp. 120-121, 733-739. Allyn & Bacon, Boston.
-
(1963)
Organic Chemistry
, pp. 120-121
-
-
Morrison, R.T.1
Boyd, R.N.2
-
32
-
-
0018864318
-
Epidemiologic studies of workers exposed to acrylonitrile
-
O'Berg, M. T. (1980). Epidemiologic studies of workers exposed to acrylonitrile. J. Occup. Med. 22, 245-252.
-
(1980)
J. Occup. Med.
, vol.22
, pp. 245-252
-
-
O'Berg, M.T.1
-
33
-
-
0022403626
-
Epidemiologic studies of workers exposed to acrylonitrile: An update
-
O'Berg, M. T., Chen, J. L., Burke, C. A., Walrath, J., and Pell, S. (1985). Epidemiologic studies of workers exposed to acrylonitrile: An update. J. Occup. Med. 27, 835-840.
-
(1985)
J. Occup. Med.
, vol.27
, pp. 835-840
-
-
O'Berg, M.T.1
Chen, J.L.2
Burke, C.A.3
Walrath, J.4
Pell, S.5
-
34
-
-
0002397191
-
Acrylonitrile toxicity, mechanism of action, therapeutic uses
-
Paulet, G., and Desnos, J. (1961). Acrylonitrile toxicity, mechanism of action, therapeutic uses. Arch. Int. Pharmacodyn. Ther. 131, 54-83.
-
(1961)
Arch. Int. Pharmacodyn. Ther.
, vol.131
, pp. 54-83
-
-
Paulet, G.1
Desnos, J.2
-
35
-
-
0014285440
-
The mammalian toxicity of methacrylonitrile
-
Pozzani, U. C., Kinkead, E. R., and King, J. M. (1968). The mammalian toxicity of methacrylonitrile. Am. Ind. Hyg. Assoc. J. 29, 202-210.
-
(1968)
Am. Ind. Hyg. Assoc. J.
, vol.29
, pp. 202-210
-
-
Pozzani, U.C.1
Kinkead, E.R.2
King, J.M.3
-
36
-
-
84969077380
-
A two-year carcinogenicity study with acrylonitrile following inhalation exposure to rats. Final report
-
Midland, MI
-
Quast, J. F., Schuetz, D. J., Balmer, M. F., Gushow, T. S., Park, C. N., and McKenna, M. J. (1980a). A two-year carcinogenicity study with acrylonitrile following inhalation exposure to rats. Final report. Dow Toxicol. Res. Lab., Midland, MI.
-
(1980)
Dow Toxicol. Res. Lab.
-
-
Quast, J.F.1
Schuetz, D.J.2
Balmer, M.F.3
Gushow, T.S.4
Park, C.N.5
McKenna, M.J.6
-
37
-
-
0011894465
-
A two-year toxicity and oncogenicity study with acrylonitrile incorporated into drinking water of rats. Final report
-
Midland, MI
-
Quast, J. F., Wade, C. E., Humiston, C. C., Carreon, R. M., Hermann, E. A., Park, C. N., and Schwetz, B. A. (1980b). A two-year toxicity and oncogenicity study with acrylonitrile incorporated into drinking water of rats. Final report. Dow Toxicol. Res. Lab., Midland, MI.
-
(1980)
Dow Toxicol. Res. Lab.
-
-
Quast, J.F.1
Wade, C.E.2
Humiston, C.C.3
Carreon, R.M.4
Hermann, E.A.5
Park, C.N.6
Schwetz, B.A.7
-
38
-
-
0002214319
-
Top 50 chemical production stagnated last year
-
Reish, M. S. (1992). Top 50 chemical production stagnated last year. Chem. Eng. News 70, 16-22.
-
(1992)
Chem. Eng. News
, vol.70
, pp. 16-22
-
-
Reish, M.S.1
-
39
-
-
0024343102
-
Metabolism of acrylonitrile to 2-cyanoethylene oxide in F-344 rat liver microsomes and lung cells
-
Roberts, A. E., Lacy, S. A., Pilon, D., Turner, M. J., Jr., and Rickert, D. E. (1989). Metabolism of acrylonitrile to 2-cyanoethylene oxide in F-344 rat liver microsomes and lung cells. Drug. Metab. Dispos. 17, 481-486.
-
(1989)
Drug. Metab. Dispos.
, vol.17
, pp. 481-486
-
-
Roberts, A.E.1
Lacy, S.A.2
Pilon, D.3
Turner M.J., Jr.4
Rickert, D.E.5
-
41
-
-
0017762498
-
Acrylonitrile and tissue glutathione: Differential effect of acute and chronic interactions
-
Szabo, S., Baily, K. A., Boor, P. J., and Jaeger, R. J. (1977). Acrylonitrile and tissue glutathione: Differential effect of acute and chronic interactions. Biochem. Biophys. Res. Commun. 79, 32-37.
-
(1977)
Biochem. Biophys. Res. Commun.
, vol.79
, pp. 32-37
-
-
Szabo, S.1
Baily, K.A.2
Boor, P.J.3
Jaeger, R.J.4
-
42
-
-
0018824370
-
Pathogenesis of experimental adrenal hemorrhagic necrosis ("apoplexy"). Ultrastructural, biochemical, neuropharmacological and blood coagulation studies with acrylonitrile in the rat
-
Szabo, S., Huttner, I., Kovacs, K., Horvath, E., Szabo, D., and Horner, H. C. (1980). Pathogenesis of experimental adrenal hemorrhagic necrosis ("apoplexy"). Ultrastructural, biochemical, neuropharmacological and blood coagulation studies with acrylonitrile in the rat. Lab. Invest. 42, 533-546.
-
(1980)
Lab. Invest.
, vol.42
, pp. 533-546
-
-
Szabo, S.1
Huttner, I.2
Kovacs, K.3
Horvath, E.4
Szabo, D.5
Horner, H.C.6
-
43
-
-
0021262884
-
Studies on the mechanism of acute toxicity of nitriles in mice
-
Tanii, H., and Hashimoto, K. (1984). Studies on the mechanism of acute toxicity of nitriles in mice. Arch. Toxicol. 55, 47-54.
-
(1984)
Arch. Toxicol.
, vol.55
, pp. 47-54
-
-
Tanii, H.1
Hashimoto, K.2
-
44
-
-
0023640335
-
Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: Influence of dose and route of administration
-
Tardif, R., Talbot, D., Gerin, M., and Brodeur, J. (1987). Urinary excretion of mercapturic acids and thiocyanate in rats exposed to acrylonitrile: Influence of dose and route of administration. Toxicol. Lett. 39, 255-261.
-
(1987)
Toxicol. Lett.
, vol.39
, pp. 255-261
-
-
Tardif, R.1
Talbot, D.2
Gerin, M.3
Brodeur, J.4
-
45
-
-
0028131146
-
Determination of tissue partition coefficients for volatile tissue-reactive chemicals: Acrylonitrile and its metabolite 2-cyanoethylene oxide
-
Teo, S. K., Kedderis, G. L., and Gargas, M. L. (1994). Determination of tissue partition coefficients for volatile tissue-reactive chemicals: Acrylonitrile and its metabolite 2-cyanoethylene oxide. Toxicol. Appl. Pharmacol. 128, 92-96.
-
(1994)
Toxicol. Appl. Pharmacol.
, vol.128
, pp. 92-96
-
-
Teo, S.K.1
Kedderis, G.L.2
Gargas, M.L.3
-
46
-
-
0002250291
-
The technique of whole body autoradiography. Cryosection of large specimens. Special issue on whole body autoradiography. Science tools
-
Uppsaala, Sweden
-
Ullberg, S. (1977). The technique of whole body autoradiography. Cryosection of large specimens. Special issue on whole body autoradiography. Science Tools, The LKB Instrument Journal, Uppsaala, Sweden.
-
(1977)
The LKB Instrument Journal
-
-
Ullberg, S.1
-
47
-
-
0027517417
-
Comparison of cancer risks projected from animal bioassays to epidemiologic studies of acrylonitrile exposed workers
-
Ward, C. E., and Starr, T. B. (1993). Comparison of cancer risks projected from animal bioassays to epidemiologic studies of acrylonitrile exposed workers. Regul. Toxicol. Pharmacol. 18, 214-232.
-
(1993)
Regul. Toxicol. Pharmacol.
, vol.18
, pp. 214-232
-
-
Ward, C.E.1
Starr, T.B.2
|