Acute renal failure in dogs after the ingestion of grapes or raisins: A retrospective evaluation of 43 dogs (1992-2002)

Journal of Veterinary Internal Medicine

Volumn 19, Issue 5, 2005, Pages 663-674

  Eubig, Paul A ^a   Brady, Melinda S ^b   Gwaltney Brant, Sharon M ^a   Khan, Safdar A ^a   Mazzaferro, Elisa M ^c   Morrow, Carla M K ^b  

^a ASPCA ANIMAL POISON CONTROL CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c Wheat Ridge Animal Hospital   (United States)

Author keywords

Calcium X phosphorus product; Canine; Clinical toxicology; Hypercalcemia; Kidneys

Indexed keywords

CREATININE; PHOSPHATE;

ACUTE KIDNEY FAILURE; ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; DIARRHEA; DIFFERENTIAL DIAGNOSIS; DOG; DOG DISEASE; FEMALE; GRAPE; HYPERCALCEMIA; KIDNEY; MALE; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; UREA NITROGEN BLOOD LEVEL; UREMIA; VOMITING;

ANIMALS; BLOOD UREA NITROGEN; CREATININE; DIAGNOSIS, DIFFERENTIAL; DIARRHEA; DOG DISEASES; DOGS; FEMALE; HYPERCALCEMIA; KIDNEY; KIDNEY FAILURE, ACUTE; MALE; PHOSPHATES; PROGNOSIS; RETROSPECTIVE STUDIES; UREMIA; VITIS; VOMITING;

ANIMALIA; ATAXIA; CANIS FAMILIARIS; VITACEAE; VITIS SP.;

EID: 26844516069     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2005)19[663:ARFIDA]2.0.CO;2     Document Type: Article

References (57)

1. Nelson KE. The grape. In: Eskin NAM, ed. Quality and Preservation of Fruits. Boca Raton, FL: CRC Press; 1991:125-167.
2. US Department of Agriculture. Citrus Fruits. 2003 Summary. US Department of Agriculture, National Agricultural Statistics Service, 2003. Available at: http://usda.mannlib.cornell.edu/reports/nassr/fruit/. Accessed August 27, 2004.
3. US Department of Agriculture. Noncitrus Fruits and Nuts. 2003 Summary. US Department of Agriculture, National Agricultural Statistics Service, 2004. Available at: http://usda.mannlib.cornell.edu/reports/nassr/fruit/. Accessed August 27, 2004.
4. Galet P. Grape Varieties. London, United Kingdom: Cassell Illustrated; 2002:6-11.
5. California Agricultural Statistics Service. California Grape Acreage - 2003. California Agricultural Statistics Service, 2004. Available at: ftp://www.nass.usda.gov/pub/nass/ca/Acreage/2003/200306gabtb00.pdf. Accessed August 27, 2004.
6. US Department of Agriculture. World Table Grape Situation and Outlook - April 2004. US Department of Agriculture, Foreign Agricultural Service, 2004. Available at: http://www.fas.usda.gov/htp/horticulture/grapes.html. Accessed August 27, 2004.
7. Striegler RK, Berg GT, Morris JR. Raisin production and processing. In: Somogyi LP, Barrett DM, Hui YH, eds. Processing Fruits: Science and Technology, Vol 2. Major Processed Products. Lancaster, PA: Technomic Publishing Co; 1996:235-263.
8. US Department of Agriculture. California's Central Valley: Center of U.S. Raisin Industry. Fruit and Tree Nuts Outlook/FTS-303/Mar. 25, 2003: 20-24. US Department of Agriculture, Economic Research Service, 2003. Available at: http://ers.usda.gov/Briefing/FruitAndTreeNuts. Accessed August 27, 2004.
9. Gwaltney-Brant S, Holding JK, Donaldson CW, et al. Renal failure associated with the ingestion of grapes or raisins in dogs. J Am Vet Med Assoc 2001;218:1555-1556.
10. Penny D, Henderson SM, Brown PJ. Raisin poisoning in a dog. Vet Rec 2003;152:308.
11. Campbell A, Bates N. Raisin poisoning in dogs. Vet Rec 2003;152:376.
12. Mazzaferro EM, Eubig PA, Hackett TB, et al. Acute renal failure associated with raisin or grape ingestion in 4 dogs. J Vet Emerg Crit Care 2004;14:203-212.
13. Behrend EN, Grauer GF, Mani I, et al. Hospital-acquired acute renal failure in dogs: 29 Cases (1983-1992). J Am Vet Med Assoc 1996;208:537-541.
14. Lane IF, Grauer GF, Fettman MJ. Acute renal failure. Part II. Diagnosis, management, and prognosis. Comp Cont Ed Pract Vet 1994;16:625-645.
15. Burn DJ, Bates D. Neurology and the kidney. J Neurol Neurosurg Psychiatr 1998;65:810-821.
16. Wolf AM. Canine uremic encephalopathy. J Am Anim Hosp Assoc 1980;16:735-738.
17. Kruger JM, Osborne CA, Nachreiner RA, et al. Hypercalcemia and renal failure. Vet Clin North Am Small Anim Pract 1996;26:1417-1445.
18. Talcott PA, Mather GG, Kowitz EH. Accidental ingestion of a cholecalciferol-containing rodent bait in a dog. Vet Hum Toxicol 1991;33:252-256.
19. Milliner DS, Zinsmeister AR, Lieberman E, et al. Soft tissue calcification in pediatric patients with end-stage renal disease. Kidney Int 1990;38:931-936.
20. Chew DJ. Fluid therapy during intrinsic renal failure. In: DiBartola SP, ed. Fluid Therapy in Small Animal Practice, 2nd ed. Philadelphia, PA: WB Saunders; 2000:410-427.
21. Labato MA. Strategies for management of acute renal failure. Vet Clin North Am Small Anim Pract 2001;31:1265-1287.
22. Finkel KW, DuBose TD Jr. Metabolic acidosis. In: DuBose TD Jr, Hamm LL, eds. Acid-base and Electrolyte Disorders: A Companion to Brenner & Rector's The Kidney. Philadelphia, PA: Elsevier Science; 2002:55.
23. Saunders HM. Ultrasonography of the pancreas. Probl Vet Med 1991;3:583-603.
24. Cornelius LM, Finco DR, Culver DH. Physiologic effects of rapid infusion of Ringer's lactate solution into dogs. Am J Vet Res 1978;39:1185-1190.
25. Lamb CR. Pancreatic edema in dogs with hypoalbuminemia or portal hypertension. J Vet Intern Med 1999;13:498-500.
26. Hess RS, Saunders HM, Van Winkle TJ, et al. Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in dogs with fatal acute pancreatitis: 70 Cases (1986-1995). J Am Vet Med Assoc 1998;213:665-670.
27. Kang JY. The gastrointestinal tract in uremia. Dig Dis Sci 1993;38:257-268.
28. Neuman NB. Acute pancreatic hemorrhage associated with iatrogenic hypercalcemia in a dog. J Am Vet Med Assoc 1975;166:381-383.
29. Frick TW, Mithofer K, Fernandez-del Castillo C, et al. Hypercalcemia causes acute pancreatitis by pancreatic secretory block, intracellular zymogen accumulation, and acinar cell injury. Am J Surg 1995;169:167-172.
30. Vaden SL, Levine J, Breitschwerdt EB. A retrospective case-control of acute renal failure in 99 dogs. J Vet Intern Med 1997;11:58-64.
31. Thrall MA, Grauer GF, Mero KN. Clinicopathologic findings in dogs and cats with ethylene glycol intoxication. J Am Vet Med Assoc 1984;184:37-41.
32. Grauer GF. Prevention of acute renal failure. Vet Clin North Am Small Anim Pract 1996;26:1447-1459.
33. Brown SA, Engelhardt JA. Drug-related nephropathies. Part I. Mechanisms, diagnosis, and management. Comp Cont Ed Pract Vet 1987;9:148-160.
34. de Broe ME, Roch-Ramel F. Renal handling of drugs and xenobiotics. In: de Broe ME, Porter GA, Bennett WM, et al, eds. Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals. Dordrecht, The Netherlands: Kluwer; 1998:13-30.
35. Maxie MG. The urinary system. In: Jubb KVF, Kennedy PC, Palmer N, eds. Pathology of Domestic Animals, 4th ed, Vol 2. San Diego, CA: Academic Press; 1993:487-489.
36. Eaton DL, Klaassen CD. Principles of toxicology. In: Klaassen CD, ed. Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th ed. New York, NY: McGraw-Hill; 2001:15-26.
37. Rademaker M. Do women have more adverse drug reactions? Am J Clin Dermatol 2001;2:349-351.
38. Carlton WW, Engelhardt JA. Chloroform nephrosis, male mouse. In: Jones TC, Mohr U, Hunt RD, eds. Urinary System. Monographs on Pathology of Laboratory Animals. New York, NY: Springer-Verlag; 1986:225-229.
39. Borghoff SJ, Short BG, Swenberg JA. Biochemical mechanisms and pathobiology of α 2u-globulin nephropathy. Annu Rev Pharmacol Toxicol 1990;30:349-367.
40. Rumbeiha WK, Fitzgerald SD, Kruger JM, et al. Use of pamidronate disodium to reduce cholecalciferol-induced toxicosis in dogs. Am J Vet Res 2000;61:9-13.
41. Grauer GF, Thrall MA, Henre BA, et al. Early clinicopathologic findings in dogs ingesting ethylene glycol. Am J Vet Res 1984;45:2299-2303.
42. Hall JO. Lily nephrotoxicity. In: August JR, ed. Consultations in Feline Internal Medicine 4. Philadelphia, PA: WB Saunders; 2001:308-310.
43. Langston CE. Acute renal failure caused by lily ingestion in six cats. J Am Vet Med Assoc 2002;220:49-52.
44. Adin CA, Cowgill LD. Treatment and outcome of dogs with leptospirosis: 36 Cases (1990-1998). J Am Vet Med Assoc 2000;216:371-375.
45. Greene CE, Miller MA, Brown CA. Leptospirosis. In: Greene CE, ed. Infectious Diseases of the Dog and Cat, 2nd ed. Philadelphia, PA: WB Saunders; 1998:273-281.
46. Bolin CA. Diagnosis of leptospirosis: A reemerging disease of companion animals. Semin Vet Med Surg (Small Anim) 1996;11:166-171.
47. Allen TA, Jaenke RS. Pyelonephritis in the dog. Comp Cont Ed Pract Vet 1985;7:421-428.
48. Drusch S, Ragab W. Mycotoxins in fruits, fruit juices, and dried fruits. J Food Prot 2003;66:1514-1527.
49. Szczech GM, Carlton WW, Tuite J. Ochratoxicosis in beagle dogs. II. Pathology. Vet Pathol 1973;10:219-231.
50. plasma. Toxicology 1996;106:167-177.
51. Krogh P. Role of ochratoxin in disease causation. Food Chem Toxicol 1992;30:213-224.
52. Cabras P, Angioni A. Pesticide residues in grapes, wine, and their processing products. J Agric Food Chem 2000;48:967-973.
53. US Food and Drug Administration. Pesticide Program Residue Monitoring. 2002 Report and Database. US Food and Drug Administration, Center for Food Safety and Applied Nutrition, 2004. Available at: http://www.cfsan.fda.gov/~dms/ pesrpts.html. Accessed August 27, 2004.
54. Eshel G, Broide E, Azizi E. Phytobezoar following raisin ingestion in children. Pediatr Emerg Care 1988;4:192-193.
55. Rosendale ME. Decontamination strategies. Vet Clin North Am Small Anim Pract 2002;32:311-321.
56. Adams WH, Toal RL, Breider MA. Ultrasonographic findings in dogs and cats with oxalate nephrosis attributed to ethylene glycol intoxication: 15 Cases (1984-1988). J Am Vet Med Assoc 1991;199:492-496.
57. Poortinga EW, Hungerford LL. A case-control study of acute ibuprofen toxicity in dogs. Prev Vet Med 1998;35:115-124.