Evaluation of renal function in rhesus monkeys and comparison to beagle dogs following oral administration of the organic acid triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid)

Fundamental and Applied Toxicology

Volumn 36, Issue 1, 1997, Pages 47-53

  Timchalk, C ^a   Finco, D R ^b   Quast, J F ^a  

^a DOW CHEMICAL COMPANY   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; CARBOXYLIC ACID; PHENOLSULFONPHTHALEIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOG; DOSE RESPONSE; GLOMERULUS FILTRATION RATE; INULIN CLEARANCE; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; RHESUS MONKEY; SPECIES DIFFERENCE; TRICLOPYR; UREA NITROGEN BLOOD LEVEL;

EID: 26844507568     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.2285     Document Type: Article

References (30)

1. Altman, P. L., and Dittmer, D. S. (1974). Renal Function Test: Vertebrates. In Biology Data Book, 2nd ed., Vol. 3, pp. 562-572. Federation of Amer. Society for Exp. Biol., Bethesda, MD.
2. Bratton, A. C., and Marshall, E. K., Jr. (1939). A new coupling component for sulfanilamide determination. J. Biol. Chem. 128, 537-550.
3. Carmichael, N. G., Nolan, R. J., Perkins, J. M., Davies, R., and Warrington, S. J. (1989). Oral and dermal pharmacokinetics of triclopyr in human volunteers. Hum. Toxicol. 8, 431-437.
4. Cherkofsky, S. C. (1995). 1-Aminocyclopropanecarboxylic acid: Mouse to man interspecies pharmacokinetic comparisons and allometric relationships. J. Pharmacol. Sci. 84(10), 1231-1235.
5. Cole, B. R., Giangiacomo, J., Inglefinger, J. R., and Robson, A. M. (1972). Measurement of renal function without urine collection. N. Engl. J. Med. 287, 1109-1114.
6. Duncan, J. R., and Prasse, K. W. (1986). Veterinary Laboratory Medicine -Clinical Pathology, 2nd ed. Iowa State Univ. Press, Ames, IA.
7. Eisenbrandt, D. L., Landry, T. D., Firchau, H. M., Tsuda, S., and Quast, J. F. (1988). Dietary chronic toxicity and oncogenicity studies of triclopyr in rats and mice. Toxicologist 8, 704.
8. Finco, D. R. (1971). Simultaneous determination of phenolsulfonphthalein excretion and endogenous creatinine clearance in the normal dog. J. Am. Vet. Med. Assoc. 159, 336-340.
9. Finco, D. R. (1980). Kidney function. In Clinical Biochemistry of Domestic Animals (J. J. Kaneko, Ed.), pp. 337-400. Academic Press, New York.
10. Finco, D. R. (1989). Kidney function. In Clinical Biochemistry of Domestic Animals (J. J. Kaneko, Ed.), pp. 496-542. Academic Press, New York.
11. Finco, D. R. (1993). Endogenous creatinine clearance measurement of glomerular filtration rate in dogs, enzymatic method of creatinine assay. Am. J. Vet. Res. 54, 1575-1578.
12. Foreman, J. W. (1984). Renal handling of urate and other organic acids. In Canine Nephrology (K. C. Bovee, Ed.), Chap. 7, pp. 135-151. Harwal.
13. Gehring, P. J., and Betso, J. E. (1978). Phenoxy acids: Effects and fate in mammals. In Chlorinated Phenoxy Acids and Their Dioxins (C. Ramel, Ed.), Vol. 27, pp. 122-133. Ecol. Bull., Stockholm.
14. Heyrovsky, A. (1956). A new method for the determination of inulin in plasma and urine. Clin. Chim. Acta 1, 470-474.
15. Hook, J. B., Bailie, M. D., Johnson, J. T., and Gehring, P. J. (1974). In vitro analysis of transport of 2,4,5-trichlorophenoxyacetic acid by rat and dog kidney. Food Cosmet. Toxicol. 12, 209-218.
16. Hook, J. B., Cardona, R., Osborn, J. L., and Bailie, M. D. (1975). The renal handling of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) in the dog. Food Cosmet. Toxicol 14, 19-23.
17. Landry, T. D., Eisenbrandt, D. L., Gushow, T. S., Phillips, J. E., and Wackerly, D. L. (1985). Triclopyr: 13-week dietary toxicity study and 4-week pharmacokinetic study in Fischer 344 rats. Toxicologist 5, 1.
18. Mann, W. A., Welzel, G. E., Goldstein, R. S., Sozio, R. S., Cyronak, M. J., Kao, J., and Kinter, L. B. (1991). Characterization of the renal effects and renal elimination of sulotroban in the dog. J. Pharmacol. Exp. Ther. 259(3), 1231-1240.
19. Ochwadt, B. K., and Pitts, R. F. (1962). Disparity between phenol red and diodrast clearances in the dog. Am. J. Physiol. 187, 318-322.
20. Osborne, C. A., Low, D. G., and Finco, D. R. (1972). Canine and Feline Urology, pp. 70-73. Saunders, Philadelphia, PA.
21. Piper, W. N., Rose, J. Q., Leng, M. L., an Gehring, P. J. (1973). The fate of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) following oral administration to rats and dogs. Toxicol. Appl. Pharmacol. 26, 339-351.
22. Russel, F. G. M., Wouterse, A. C., and Van Ginneken, C. A. M. (1987). Physiological based pharmacokinetic model for the renal clearance of salicyluric acid and the interaction with phenolsulfonphthalein in the dog. Drug Metab. Dispos. 15, 695-701.
23. Russel, F. G. M., Wouterse, A. C., and Van Ginneken, C. A. M. (1989). Physiological based pharmacokinetic model for the renal clearance of iodopyracet and the interaction with probenecid in the dog. Biopharm. Drug Dispos. 10, 137-152.
24. Schuster, V. L., and Seldin, D. W. (1992). Renal clearance. In The Kidney: Physiology and Pathophysiology (D. W. Seldin and G. Giebisch, Eds.), pp. 943-973. Raven Press, New York.
25. Smith, H. W., Finkelstein, N., Aliminosa, L., Crawford, B., and Graber, M. (1945). The renal clearance of substituted hippuric acid derivatives and other aromatic acids in dog and man. J. Clin. Invest. 24, 388-404.
26. Steel, R. G. D., and Torrie, J. H. (1980). Principles and Procedures of Statistics, 2nd ed., McGraw-Hill, New York.
27. Timchalk, C., Dryzga, M. D., and Kastl, P. E. (1990). Pharmacokinetics and metabolism of triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) in Fischer 344 rats. Toxicology 62, 71-87.
28. Timchalk, C., Lacher, J. W., Dryzga, M. D., Pottenger, L. H., and Hansen, S. C. (1996). Pharmacokinetics and renal clearance of triclopyr in the male beagle dog. Toxicologist 30(2), 265.
29. Weiner, I. M. (1973). Transport of weak acids and bases. In Handbook of Physiology, Section 8: Renal Physiology, Chap. 17, pp. 521-554. American Physiol. Soc. Williams & Wilkins, Baltimore, MD.
30. Worthing, C. R. (1987). The Pesticide Manual, 8th ed., p. 824. British Crop Protection Council.