-
1
-
-
0033849075
-
Overactive bladder significantly affects quality of life
-
Abrams, P., Kelleher, C.J., Kerr, L.A., Rogers, R.G. Overactive bladder significantly affects quality of life. Am J Manag Care 2000, 6(Suppl 11): S580-90.
-
(2000)
Am J Manag Care
, vol.6
, Issue.SUPPL. 11
-
-
Abrams, P.1
Kelleher, C.J.2
Kerr, L.A.3
Rogers, R.G.4
-
2
-
-
0035725404
-
How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study
-
Milsom, I., Abrams, P., Cardozo, L., Roberts, R.G., Thuroff, J., Wein, A.J. How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int 2001, 87: 760-6.
-
(2001)
BJU Int
, vol.87
, pp. 760-766
-
-
Milsom, I.1
Abrams, P.2
Cardozo, L.3
Roberts, R.G.4
Thuroff, J.5
Wein, A.J.6
-
3
-
-
0141566431
-
Prevalence and burden of overactive bladder in the United States
-
Stewart, W.F., Van Rooyen, J.B., Cundiff, G.W., et al. Prevalence and burden of overactive bladder in the United States. World J Urol 2003, 20: 327-36.
-
(2003)
World J Urol
, vol.20
, pp. 327-336
-
-
Stewart, W.F.1
Van Rooyen, J.B.2
Cundiff, G.W.3
-
6
-
-
0031985364
-
Pharmacokinetics and metabolism of darifenacin in the mouse, rat, dog, and man
-
Beaumont, K.C., Cussans, N.J., Nichols, D.J., Smith, D.A. Pharmacokinetics and metabolism of darifenacin in the mouse, rat, dog, and man. Xenobiotica 1998, 28: 63-75.
-
(1998)
Xenobiotica
, vol.28
, pp. 63-75
-
-
Beaumont, K.C.1
Cussans, N.J.2
Nichols, D.J.3
Smith, D.A.4
-
8
-
-
0033553589
-
Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland
-
Moriya, H., Takagi, Y., Nakanishi, T., Hayashi, M., Tani, T., Hitotsu, I. Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland. Life Sci 1999, 64: 2351-8.
-
(1999)
Life Sci
, vol.64
, pp. 2351-2358
-
-
Moriya, H.1
Takagi, Y.2
Nakanishi, T.3
Hayashi, M.4
Tani, T.5
Hitotsu, I.6
-
12
-
-
0035992628
-
3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland
-
3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland. Naunyn-Schmiedeberg's Arch Pharmacol 2002, 366: 97-103.
-
(2002)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.366
, pp. 97-103
-
-
Ikeda, K.1
Kobayashi, S.2
Suzuki, M.3
-
13
-
-
0002491968
-
3 antagonist
-
3 antagonist [abstract]. Pharmacol Res 1995, 31(Suppl): 54.
-
(1995)
Pharmacol Res
, vol.31
, Issue.SUPPL.
, pp. 54
-
-
Wallis, R.M.1
Burges, R.A.2
Cross, P.E.3
MacKenzie, A.R.4
Newgreen, D.T.5
Quinn, P.6
-
14
-
-
0002774274
-
Comparison of the functional muscarinic receptor selectivity of darifenacin with tolterodine and oxybutynin
-
Abst. 107P
-
Newgreen, D.T., Naylor, A.M. Comparison of the functional muscarinic receptor selectivity of darifenacin with tolterodine and oxybutynin [abstract]. Br J Pharmacol 1996, 117(Suppl): Abst. 107P.
-
(1996)
Br J Pharmacol
, vol.117
, Issue.SUPPL.
-
-
Newgreen, D.T.1
Naylor, A.M.2
-
15
-
-
1242301622
-
3 antimuscarinic agent, in the anesthetised dog
-
Abst. 515
-
3 antimuscarinic agent, in the anesthetised dog [abstract]. Eur Urol Suppl 2002, 1(1): 131, Abst. 515.
-
(2002)
Eur Urol Suppl
, vol.1
, Issue.1
, pp. 131
-
-
Gupta, P.1
Anderson, C.2
Carter, A.3
Casey, J.4
Newgreen, D.5
-
16
-
-
8844239350
-
3 selectivity
-
Abst. 458
-
3 selectivity [abstract]. Eur Urol Suppl 2003, 2(1): 117, Abst. 458
-
(2003)
Eur Urol Suppl
, vol.2
, Issue.1
, pp. 117
-
-
Alexandrou, A.1
Claringbold, A.2
Harris, J.3
McAllister, K.4
Pullen, S.5
Gupta, P.6
Clarke, N.P.7
-
17
-
-
0000068279
-
The effects of darifenacin and oxybutynin on bladder function and salivation in the conscious rat
-
Abst. 205P
-
Williamson, I.J.R., Newgreen, D.T., Naylor, A.M. The effects of darifenacin and oxybutynin on bladder function and salivation in the conscious rat [abstract]. Br J Pharmacol 1997, 120(Suppl): Abst. 205P.
-
(1997)
Br J Pharmacol
, vol.120
, Issue.SUPPL.
-
-
Williamson, I.J.R.1
Newgreen, D.T.2
Naylor, A.M.3
-
18
-
-
3142619868
-
In vivo bladder selectivity of the novel muscarinic antagonist, darifenacin, in the conscious minipig
-
Abst. 202P
-
Davies, C.L., Dodd, M.G., Merner, P.A., Rankin, A.J. In vivo bladder selectivity of the novel muscarinic antagonist, darifenacin, in the conscious minipig [abstract]. Br J Pharmacol 1996, 117(Suppl): Abst. 202P.
-
(1996)
Br J Pharmacol
, vol.117
, Issue.SUPPL.
-
-
Davies, C.L.1
Dodd, M.G.2
Merner, P.A.3
Rankin, A.J.4
-
19
-
-
0343274607
-
Effect of darifenacin on muscarinic responses in normal and unstable human detrusor smooth muscle cells
-
Abst. 9a
-
Chua, C.B., Harris, D.R., Marsh, K.A., Hill, S.J., Bates, C.P. Effect of darifenacin on muscarinic responses in normal and unstable human detrusor smooth muscle cells [abstract]. Neurourol Urodyn 1997, 16: 355-6, Abst. 9a.
-
(1997)
Neurourol Urodyn
, vol.16
, pp. 355-356
-
-
Chua, C.B.1
Harris, D.R.2
Marsh, K.A.3
Hill, S.J.4
Bates, C.P.5
-
20
-
-
26844571966
-
Comparison of pharmacological effects on various antimuscarinic drugs on human isolated urinary bladder
-
Abst. 57
-
Yoshida, M., Miyamae, K., Murakami, S., Yono, M., Inadome, A., Ueda, S. Comparison of pharmacological effects on various antimuscarinic drugs on human isolated urinary bladder [abstract]. Neurourol Urodyn 2001, 20: 462-3, Abst. 57.
-
(2001)
Neurourol Urodyn
, vol.20
, pp. 462-463
-
-
Yoshida, M.1
Miyamae, K.2
Murakami, S.3
Yono, M.4
Inadome, A.5
Ueda, S.6
-
21
-
-
0344394920
-
Pharmacological effects of darifenacin on human isolated urinary bladder
-
Miyamae, K., Yoshida, M., Murakami, S., et al. Pharmacological effects of darifenacin on human isolated urinary bladder. Pharmacology 2003, 69: 205-11.
-
(2003)
Pharmacology
, vol.69
, pp. 205-211
-
-
Miyamae, K.1
Yoshida, M.2
Murakami, S.3
-
22
-
-
84878677688
-
Affinity of darifenacin for the p-glycoprotein efflux pump: A mechanism contributing to the CNS sparing profile?
-
December 14-16, Newcastle UK
-
Skerjanec, A., Devineni, D. Affinity of darifenacin for the p-glycoprotein efflux pump: a mechanism contributing to the CNS sparing profile? [abstract]. British Pharmacological Society Winter Meeting December 14-16, 2004, Newcastle UK.
-
(2004)
British Pharmacological Society Winter Meeting
-
-
Skerjanec, A.1
Devineni, D.2
-
23
-
-
0345374663
-
Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability
-
Kerbusch, T., Wählby, U., Milligan, P.A., Karlsson, M.O. Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability. Br J Clin Pharmacol 2003, 56: 639-52.
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 639-652
-
-
Kerbusch, T.1
Wählby, U.2
Milligan, P.A.3
Karlsson, M.O.4
-
24
-
-
8844226852
-
No effect of food on pharmacokinetics of darifenacin in multiple doses
-
Abst. 346
-
Nichols, D.J. No effect of food on pharmacokinetics of darifenacin in multiple doses [abstract]. Pharmacol Toxicol 2001, 89 (Suppl 1): 89, Abst. 346.
-
(2001)
Pharmacol Toxicol
, vol.89
, Issue.SUPPL. 1
, pp. 89
-
-
Nichols, D.J.1
-
26
-
-
84878703632
-
-
Novartis Europharm Limited, UK, October European Medicines Agency (EMEA)
-
Emselex Summary of Product Characteristics (SmPC). Novartis Europharm Limited, UK, October 2004. Available from the European Medicines Agency (EMEA): http://www.emea. eu.int/humandocs/Humans/EPAR/emselex/emse elex.htm.
-
(2004)
Emselex Summary of Product Characteristics (SmPC)
-
-
-
27
-
-
2942671579
-
Darifenacin does not affect the pharmacokinetics of a combined oral contraceptive (Microgynon®) in healthy women
-
Abst. 49(268)
-
Salvatore, S. Darifenacin does not affect the pharmacokinetics of a combined oral contraceptive (Microgynon®) in healthy women [abstract]. Int Urogynecol J 2001, 12(Suppl 3): S32, Abst. 49(268).
-
(2001)
Int Urogynecol J
, vol.12
, Issue.SUPPL. 3
-
-
Salvatore, S.1
-
28
-
-
1642276168
-
3 selective receptor antagonist, is an effective and well-tolerated once-daily treatment for overactive bladder
-
3 selective receptor antagonist, is an effective and well-tolerated once-daily treatment for overactive bladder. Eur Urol 2004, 45: 420-9.
-
(2004)
Eur Urol
, vol.45
, pp. 420-429
-
-
Haab, F.1
Stewart, L.2
Dwyer, P.3
-
30
-
-
14644417909
-
3 selective receptor antagonist
-
erratum 2005, 95: 1385-6
-
3 selective receptor antagonist. BJU Int 2005, 95: 580-6, erratum 2005, 95: 1385-6.
-
(2005)
BJU Int
, vol.95
, pp. 580-586
-
-
Steers, W.1
Corcos, J.2
Foote, J.3
Kralidis, G.4
-
32
-
-
18544379289
-
A pooled analysis of three phase III studies to investigate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist, in the treatment of overactive bladder
-
Chapple, C.R., Steers, W., Norton, P., et al. A pooled analysis of three phase III studies to investigate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist, in the treatment of overactive bladder. BJU Int 2005, 95: 993-1001.
-
(2005)
BJU Int
, vol.95
, pp. 993-1001
-
-
Chapple, C.R.1
Steers, W.2
Norton, P.3
-
33
-
-
0033021357
-
Factors involved in the success of anti-muscarinic treatment
-
Abrams, P., Larsson, G., Chapple, C., Wein, A.J. Factors involved in the success of anti-muscarinic treatment. BJU Int 1999, 83(Suppl 2): 42-7.
-
(1999)
BJU Int
, vol.83
, Issue.SUPPL. 2
, pp. 42-47
-
-
Abrams, P.1
Larsson, G.2
Chapple, C.3
Wein, A.J.4
-
34
-
-
0038244779
-
Assessment of an electronic daily diary in patients with overactive bladder
-
Quinn, P., Goka, J., Richardson, H. Assessment of an electronic daily diary in patients with overactive bladder. BJU Int 2003, 91: 647-52.
-
(2003)
BJU Int
, vol.91
, pp. 647-652
-
-
Quinn, P.1
Goka, J.2
Richardson, H.3
-
35
-
-
26844482788
-
Approaches for determining the efficacy of treatment for overactive bladder: Assessment of responder rates to darifenacin in a pooled analysis of phase III studies
-
Abst. 558
-
Abrams, P., Lheritier, K., Steel, M. Approaches for determining the efficacy of treatment for overactive bladder: assessment of responder rates to darifenacin in a pooled analysis of phase III studies [abstract]. Eur Urol Suppl 2005, 4: 142(Abst. 558).
-
(2005)
Eur Urol Suppl
, vol.4
, pp. 142
-
-
Abrams, P.1
Lheritier, K.2
Steel, M.3
-
36
-
-
21244437845
-
Urinary continence during darifenacin therapy for overactive bladder (overactive bladder): Pooled data from phase III trials
-
Abst. 229
-
Abrams, P., Foote, J., Lheritier, K. Urinary continence during darifenacin therapy for overactive bladder (overactive bladder): pooled data from phase III trials [abstract]. Eur Urol Suppl 2005, 4: 60 (Abst. 229).
-
(2005)
Eur Urol Suppl
, vol.4
, pp. 60
-
-
Abrams, P.1
Foote, J.2
Lheritier, K.3
-
37
-
-
8444252588
-
Responder rates, a better way to express drug efficacy: Data from darifenacin pooled phase III studies
-
(August 25-27, Paris, France), Abst. 389
-
Abrams, P., Foote, J., Lheritier, K., Steel, M. Responder rates, a better way to express drug efficacy: data from darifenacin pooled phase III studies [abstract]. 34th Annual Meeting of the International Continence Society (August 25-27, Paris, France) 2004, Abst. 389 http://www. continet. org/publications/ 2004/pdf/0389.pdf.
-
(2004)
34th Annual Meeting of the International Continence Society
-
-
Abrams, P.1
Foote, J.2
Lheritier, K.3
Steel, M.4
-
38
-
-
0011884156
-
3 antagonist for overactive bladder: Comparison with oxybutynin on ambulatory urodynamic monitoring and salivary flow
-
(September 18-21, Seoul, South Korea), Abst 221
-
3 antagonist for overactive bladder: comparison with oxybutynin on ambulatory urodynamic monitoring and salivary flow [abstract]. 31st Annual Meeting of the International Continence Society (September 18-21, Seoul, South Korea) 2001, Abst 221. http://www.continet.org/publications/2001/ pdf/0221.pdf.
-
(2001)
31st Annual Meeting of the International Continence Society
-
-
Mundy, A.R.1
Abrams, P.2
Chapple, C.R.3
Neal, D.E.4
-
39
-
-
32044463731
-
3 SRA), compared with oxybutynin in the treatment of patients with overactive bladder
-
in press
-
3 SRA), compared with oxybutynin in the treatment of patients with overactive bladder. World J Urol 2005, in press.
-
(2005)
World J Urol
-
-
Zinner, N.1
Tuttle, J.2
Marks, L.3
-
40
-
-
33747887310
-
3 selective receptor antagonist, compared with oxybutynin in the treatment of patients with overactive bladder
-
(August 25-27, Paris, France), Abst. 378
-
3 selective receptor antagonist, compared with oxybutynin in the treatment of patients with overactive bladder [abstract]. 34th Annual Meeting of the International Continence Society, (August 25-27, Paris, France) 2004, Abst. 378 http://www. continet.org/publications/2004/pdf/ 0378.pdf.
-
(2004)
34th Annual Meeting of the International Continence Society
-
-
Zinner, N.1
Tuttle, J.2
Marks, L.3
-
41
-
-
0030802061
-
Explicit criteria for determining potentially inappropriate medication use by the elderly
-
Beers, M.H. Explicit criteria for determining potentially inappropriate medication use by the elderly. Arch Intern Med 1997, 157: 1531-6.
-
(1997)
Arch Intern Med
, vol.157
, pp. 1531-1536
-
-
Beers, M.H.1
-
42
-
-
0345600187
-
Updating the Beers Criteria for potentially inappropriate medication use in older adults
-
Pick, D.M., Cooper, J.W., Wade, W.E., Waller, J.L., Maclean, J.R., Beers, M.H. Updating the Beers Criteria for potentially inappropriate medication use in older adults. Arch Intern Med 2003, 163: 2716-24.
-
(2003)
Arch Intern Med
, vol.163
, pp. 2716-2724
-
-
Pick, D.M.1
Cooper, J.W.2
Wade, W.E.3
Waller, J.L.4
Maclean, J.R.5
Beers, M.H.6
-
44
-
-
0030667817
-
A new questionnaire to assess the quality of life of urinary incontinent women
-
Kelleher, C.J., Cardozo, L.D., Khullar, V., Salvatore, S. A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 1997, 104: 1374-9.
-
(1997)
Br J Obstet Gynaecol
, vol.104
, pp. 1374-1379
-
-
Kelleher, C.J.1
Cardozo, L.D.2
Khullar, V.3
Salvatore, S.4
-
45
-
-
0038626769
-
Multinational study of reliability and validity of the King's Health Questionnaire in patients with overactive bladder
-
Reese, P.R., Pleil, A.M., Okano, G.J., Kelleher, C.J. Multinational study of reliability and validity of the King's Health Questionnaire in patients with overactive bladder. Qual Life Res 2003, 12: 427-42.
-
(2003)
Qual Life Res
, vol.12
, pp. 427-442
-
-
Reese, P.R.1
Pleil, A.M.2
Okano, G.J.3
Kelleher, C.J.4
-
46
-
-
26844548532
-
3 selective receptor antagonist, in patients with overactive bladder
-
Abst. 1136
-
3 selective receptor antagonist, in patients with overactive bladder [abstract]. BJU Int 2004, 94(Suppl 2): Abst. 1136.
-
(2004)
BJU Int
, vol.94
, Issue.SUPPL. 2
-
-
Chapple, C.1
Kelleher, C.2
Perrault, L.3
-
47
-
-
84878684643
-
Patient perceived quality of treatment is a valid method to assess the satisfaction, preference and willingness of patients to re-use treatment for overactive bladder
-
Abst. 69
-
Steel, M., Kahler, K. Patient perceived quality of treatment is a valid method to assess the satisfaction, preference and willingness of patients to re-use treatment for overactive bladder [abstract]. Prog Urol 2004, 14(Suppl 3): 23, Abst. 69.
-
(2004)
Prog Urol
, vol.14
, Issue.SUPPL. 3
, pp. 23
-
-
Steel, M.1
Kahler, K.2
-
48
-
-
84878686121
-
Patient satisfaction, preference, and willingness to reuse darifenacin in the treatment of overactive bladder
-
Abst. 1139
-
Glavind, K., Perrault, L. Patient satisfaction, preference, and willingness to reuse darifenacin in the treatment of overactive bladder [abstract]. BJU Int 2004, 94(Suppl 2): Abst. 1139.
-
(2004)
BJU Int
, vol.94
, Issue.SUPPL. 2
-
-
Glavind, K.1
Perrault, L.2
-
49
-
-
84878692157
-
Darifenacin versus oxybutynin for overactive bladder (OAB)
-
(October 13-17, Orlando, USA), Abst./Poster 4029
-
Abrams, P., Steel, M., Ebinger, U. Darifenacin versus oxybutynin for overactive bladder (OAB) [abstract]. WONCA/AAFP meeting (October 13-17, Orlando, USA) 2004, Abst./Poster 4029.
-
(2004)
WONCA/AAFP Meeting
-
-
Abrams, P.1
Steel, M.2
Ebinger, U.3
-
50
-
-
33745196639
-
Central nervous system (CNS)-related adverse events in patients with overactive bladder (overactive bladder) treated with darifenacin versus tolterodine
-
Abst. 1134
-
Foote, J., Glavind, K., Kay, G. Central nervous system (CNS)-related adverse events in patients with overactive bladder (overactive bladder) treated with darifenacin versus tolterodine [abstract]. BJU Int 2004, 94(Suppl 2): Abst. 1134.
-
(2004)
BJU Int
, vol.94
, Issue.SUPPL. 2
-
-
Foote, J.1
Glavind, K.2
Kay, G.3
-
51
-
-
0036664806
-
3 receptor selectivity
-
3 receptor selectivity. Eur Urol Suppl 2002, 1 (Suppl): 23-8.
-
(2002)
Eur Urol Suppl
, vol.1
, Issue.SUPPL.
, pp. 23-28
-
-
Andersson, K.-E.1
-
52
-
-
0031583646
-
Oxybutynin and cognitive dysfunction
-
Donnellan, C.A., Fook, L., McDonald, P., Playfer, J.R. Oxybutynin and cognitive dysfunction. BMJ 1997, 315: 1363-4.
-
(1997)
BMJ
, vol.315
, pp. 1363-1364
-
-
Donnellan, C.A.1
Fook, L.2
McDonald, P.3
Playfer, J.R.4
-
53
-
-
0038665188
-
Tolterodine and memory: Dry but forgetful
-
Womack, K.B., Heilman, K.M. Tolterodine and memory: dry but forgetful. Arch Neurol 2003, 60: 771-3.
-
(2003)
Arch Neurol
, vol.60
, pp. 771-773
-
-
Womack, K.B.1
Heilman, K.M.2
-
54
-
-
26844464517
-
Pharmacodynamic effects of darifenacin, a muscarinic receptor antagonist for the treatment of overactive bladder, in healthy volunteers
-
in press
-
Kay, G., Wesnes, K. Pharmacodynamic effects of darifenacin, a muscarinic receptor antagonist for the treatment of overactive bladder, in healthy volunteers. BJU Int 2005, in press.
-
(2005)
BJU Int
-
-
Kay, G.1
Wesnes, K.2
-
55
-
-
12544253619
-
Assessment of cognitive function in the elderly population: Effects of darifenacin
-
Lipton, R.B., Kolodner, K., Wesnes, K. Assessment of cognitive function in the elderly population: effects of darifenacin. J Urol 2005, 173: 493-8.
-
(2005)
J Urol
, vol.173
, pp. 493-498
-
-
Lipton, R.B.1
Kolodner, K.2
Wesnes, K.3
-
56
-
-
0029935956
-
1 muscarinic acetylcholine receptors in rat ventricular myocytes
-
1 muscarinic acetylcholine receptors in rat ventricular myocytes. Circ Res 1996, 79: 86-93.
-
(1996)
Circ Res
, vol.79
, pp. 86-93
-
-
Sharma, V.K.1
Colecraft, H.M.2
Wang, D.X.3
-
57
-
-
23944509028
-
3 selective receptor antagonist for the treatment of overactive bladder
-
3 selective receptor antagonist for the treatment of overactive bladder. J Clin Pharm 2005, 45: 1038-47.
-
(2005)
J Clin Pharm
, vol.45
, pp. 1038-1047
-
-
Serra, D.B.1
Affrime, M.B.2
Bedigian, M.P.3
|