메뉴 건너뛰기




Volumn 41, Issue 7, 2005, Pages 441-452

Darifenacin in the treatment of overactive bladder

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CIMETIDINE; CLARITHROMYCIN; DARIFENACIN; DICYCLOVERINE; DIGOXIN; DILTIAZEM; ERYTHROMYCIN; FLAVOXATE; FLECAINIDE; FLUCONAZOLE; ITRACONAZOLE; KETOCONAZOLE; MUSCARINIC M3 RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; NEFAZODONE; NELFINAVIR; OXYBUTYNIN; PAROXETINE; PROPIVERINE; QUINIDINE; RITONAVIR; TERBINAFINE; THIORIDAZINE; TOLTERODINE; TRICYCLIC ANTIDEPRESSANT AGENT; TROSPIUM CHLORIDE; VERAPAMIL; WARFARIN;

EID: 26844463381     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2005.41.7.891719     Document Type: Review
Times cited : (11)

References (57)
  • 1
    • 0033849075 scopus 로고    scopus 로고
    • Overactive bladder significantly affects quality of life
    • Abrams, P., Kelleher, C.J., Kerr, L.A., Rogers, R.G. Overactive bladder significantly affects quality of life. Am J Manag Care 2000, 6(Suppl 11): S580-90.
    • (2000) Am J Manag Care , vol.6 , Issue.SUPPL. 11
    • Abrams, P.1    Kelleher, C.J.2    Kerr, L.A.3    Rogers, R.G.4
  • 2
    • 0035725404 scopus 로고    scopus 로고
    • How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study
    • Milsom, I., Abrams, P., Cardozo, L., Roberts, R.G., Thuroff, J., Wein, A.J. How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU Int 2001, 87: 760-6.
    • (2001) BJU Int , vol.87 , pp. 760-766
    • Milsom, I.1    Abrams, P.2    Cardozo, L.3    Roberts, R.G.4    Thuroff, J.5    Wein, A.J.6
  • 3
    • 0141566431 scopus 로고    scopus 로고
    • Prevalence and burden of overactive bladder in the United States
    • Stewart, W.F., Van Rooyen, J.B., Cundiff, G.W., et al. Prevalence and burden of overactive bladder in the United States. World J Urol 2003, 20: 327-36.
    • (2003) World J Urol , vol.20 , pp. 327-336
    • Stewart, W.F.1    Van Rooyen, J.B.2    Cundiff, G.W.3
  • 6
    • 0031985364 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of darifenacin in the mouse, rat, dog, and man
    • Beaumont, K.C., Cussans, N.J., Nichols, D.J., Smith, D.A. Pharmacokinetics and metabolism of darifenacin in the mouse, rat, dog, and man. Xenobiotica 1998, 28: 63-75.
    • (1998) Xenobiotica , vol.28 , pp. 63-75
    • Beaumont, K.C.1    Cussans, N.J.2    Nichols, D.J.3    Smith, D.A.4
  • 8
    • 0033553589 scopus 로고    scopus 로고
    • Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland
    • Moriya, H., Takagi, Y., Nakanishi, T., Hayashi, M., Tani, T., Hitotsu, I. Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland. Life Sci 1999, 64: 2351-8.
    • (1999) Life Sci , vol.64 , pp. 2351-2358
    • Moriya, H.1    Takagi, Y.2    Nakanishi, T.3    Hayashi, M.4    Tani, T.5    Hitotsu, I.6
  • 12
    • 0035992628 scopus 로고    scopus 로고
    • 3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland
    • 3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland. Naunyn-Schmiedeberg's Arch Pharmacol 2002, 366: 97-103.
    • (2002) Naunyn-Schmiedeberg's Arch Pharmacol , vol.366 , pp. 97-103
    • Ikeda, K.1    Kobayashi, S.2    Suzuki, M.3
  • 14
    • 0002774274 scopus 로고    scopus 로고
    • Comparison of the functional muscarinic receptor selectivity of darifenacin with tolterodine and oxybutynin
    • Abst. 107P
    • Newgreen, D.T., Naylor, A.M. Comparison of the functional muscarinic receptor selectivity of darifenacin with tolterodine and oxybutynin [abstract]. Br J Pharmacol 1996, 117(Suppl): Abst. 107P.
    • (1996) Br J Pharmacol , vol.117 , Issue.SUPPL.
    • Newgreen, D.T.1    Naylor, A.M.2
  • 17
    • 0000068279 scopus 로고    scopus 로고
    • The effects of darifenacin and oxybutynin on bladder function and salivation in the conscious rat
    • Abst. 205P
    • Williamson, I.J.R., Newgreen, D.T., Naylor, A.M. The effects of darifenacin and oxybutynin on bladder function and salivation in the conscious rat [abstract]. Br J Pharmacol 1997, 120(Suppl): Abst. 205P.
    • (1997) Br J Pharmacol , vol.120 , Issue.SUPPL.
    • Williamson, I.J.R.1    Newgreen, D.T.2    Naylor, A.M.3
  • 18
    • 3142619868 scopus 로고    scopus 로고
    • In vivo bladder selectivity of the novel muscarinic antagonist, darifenacin, in the conscious minipig
    • Abst. 202P
    • Davies, C.L., Dodd, M.G., Merner, P.A., Rankin, A.J. In vivo bladder selectivity of the novel muscarinic antagonist, darifenacin, in the conscious minipig [abstract]. Br J Pharmacol 1996, 117(Suppl): Abst. 202P.
    • (1996) Br J Pharmacol , vol.117 , Issue.SUPPL.
    • Davies, C.L.1    Dodd, M.G.2    Merner, P.A.3    Rankin, A.J.4
  • 19
    • 0343274607 scopus 로고    scopus 로고
    • Effect of darifenacin on muscarinic responses in normal and unstable human detrusor smooth muscle cells
    • Abst. 9a
    • Chua, C.B., Harris, D.R., Marsh, K.A., Hill, S.J., Bates, C.P. Effect of darifenacin on muscarinic responses in normal and unstable human detrusor smooth muscle cells [abstract]. Neurourol Urodyn 1997, 16: 355-6, Abst. 9a.
    • (1997) Neurourol Urodyn , vol.16 , pp. 355-356
    • Chua, C.B.1    Harris, D.R.2    Marsh, K.A.3    Hill, S.J.4    Bates, C.P.5
  • 20
    • 26844571966 scopus 로고    scopus 로고
    • Comparison of pharmacological effects on various antimuscarinic drugs on human isolated urinary bladder
    • Abst. 57
    • Yoshida, M., Miyamae, K., Murakami, S., Yono, M., Inadome, A., Ueda, S. Comparison of pharmacological effects on various antimuscarinic drugs on human isolated urinary bladder [abstract]. Neurourol Urodyn 2001, 20: 462-3, Abst. 57.
    • (2001) Neurourol Urodyn , vol.20 , pp. 462-463
    • Yoshida, M.1    Miyamae, K.2    Murakami, S.3    Yono, M.4    Inadome, A.5    Ueda, S.6
  • 21
    • 0344394920 scopus 로고    scopus 로고
    • Pharmacological effects of darifenacin on human isolated urinary bladder
    • Miyamae, K., Yoshida, M., Murakami, S., et al. Pharmacological effects of darifenacin on human isolated urinary bladder. Pharmacology 2003, 69: 205-11.
    • (2003) Pharmacology , vol.69 , pp. 205-211
    • Miyamae, K.1    Yoshida, M.2    Murakami, S.3
  • 22
    • 84878677688 scopus 로고    scopus 로고
    • Affinity of darifenacin for the p-glycoprotein efflux pump: A mechanism contributing to the CNS sparing profile?
    • December 14-16, Newcastle UK
    • Skerjanec, A., Devineni, D. Affinity of darifenacin for the p-glycoprotein efflux pump: a mechanism contributing to the CNS sparing profile? [abstract]. British Pharmacological Society Winter Meeting December 14-16, 2004, Newcastle UK.
    • (2004) British Pharmacological Society Winter Meeting
    • Skerjanec, A.1    Devineni, D.2
  • 23
    • 0345374663 scopus 로고    scopus 로고
    • Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability
    • Kerbusch, T., Wählby, U., Milligan, P.A., Karlsson, M.O. Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulation-dependent bioavailability. Br J Clin Pharmacol 2003, 56: 639-52.
    • (2003) Br J Clin Pharmacol , vol.56 , pp. 639-652
    • Kerbusch, T.1    Wählby, U.2    Milligan, P.A.3    Karlsson, M.O.4
  • 24
    • 8844226852 scopus 로고    scopus 로고
    • No effect of food on pharmacokinetics of darifenacin in multiple doses
    • Abst. 346
    • Nichols, D.J. No effect of food on pharmacokinetics of darifenacin in multiple doses [abstract]. Pharmacol Toxicol 2001, 89 (Suppl 1): 89, Abst. 346.
    • (2001) Pharmacol Toxicol , vol.89 , Issue.SUPPL. 1 , pp. 89
    • Nichols, D.J.1
  • 26
    • 84878703632 scopus 로고    scopus 로고
    • Novartis Europharm Limited, UK, October European Medicines Agency (EMEA)
    • Emselex Summary of Product Characteristics (SmPC). Novartis Europharm Limited, UK, October 2004. Available from the European Medicines Agency (EMEA): http://www.emea. eu.int/humandocs/Humans/EPAR/emselex/emse elex.htm.
    • (2004) Emselex Summary of Product Characteristics (SmPC)
  • 27
    • 2942671579 scopus 로고    scopus 로고
    • Darifenacin does not affect the pharmacokinetics of a combined oral contraceptive (Microgynon®) in healthy women
    • Abst. 49(268)
    • Salvatore, S. Darifenacin does not affect the pharmacokinetics of a combined oral contraceptive (Microgynon®) in healthy women [abstract]. Int Urogynecol J 2001, 12(Suppl 3): S32, Abst. 49(268).
    • (2001) Int Urogynecol J , vol.12 , Issue.SUPPL. 3
    • Salvatore, S.1
  • 28
    • 1642276168 scopus 로고    scopus 로고
    • 3 selective receptor antagonist, is an effective and well-tolerated once-daily treatment for overactive bladder
    • 3 selective receptor antagonist, is an effective and well-tolerated once-daily treatment for overactive bladder. Eur Urol 2004, 45: 420-9.
    • (2004) Eur Urol , vol.45 , pp. 420-429
    • Haab, F.1    Stewart, L.2    Dwyer, P.3
  • 32
    • 18544379289 scopus 로고    scopus 로고
    • A pooled analysis of three phase III studies to investigate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist, in the treatment of overactive bladder
    • Chapple, C.R., Steers, W., Norton, P., et al. A pooled analysis of three phase III studies to investigate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist, in the treatment of overactive bladder. BJU Int 2005, 95: 993-1001.
    • (2005) BJU Int , vol.95 , pp. 993-1001
    • Chapple, C.R.1    Steers, W.2    Norton, P.3
  • 33
    • 0033021357 scopus 로고    scopus 로고
    • Factors involved in the success of anti-muscarinic treatment
    • Abrams, P., Larsson, G., Chapple, C., Wein, A.J. Factors involved in the success of anti-muscarinic treatment. BJU Int 1999, 83(Suppl 2): 42-7.
    • (1999) BJU Int , vol.83 , Issue.SUPPL. 2 , pp. 42-47
    • Abrams, P.1    Larsson, G.2    Chapple, C.3    Wein, A.J.4
  • 34
    • 0038244779 scopus 로고    scopus 로고
    • Assessment of an electronic daily diary in patients with overactive bladder
    • Quinn, P., Goka, J., Richardson, H. Assessment of an electronic daily diary in patients with overactive bladder. BJU Int 2003, 91: 647-52.
    • (2003) BJU Int , vol.91 , pp. 647-652
    • Quinn, P.1    Goka, J.2    Richardson, H.3
  • 35
    • 26844482788 scopus 로고    scopus 로고
    • Approaches for determining the efficacy of treatment for overactive bladder: Assessment of responder rates to darifenacin in a pooled analysis of phase III studies
    • Abst. 558
    • Abrams, P., Lheritier, K., Steel, M. Approaches for determining the efficacy of treatment for overactive bladder: assessment of responder rates to darifenacin in a pooled analysis of phase III studies [abstract]. Eur Urol Suppl 2005, 4: 142(Abst. 558).
    • (2005) Eur Urol Suppl , vol.4 , pp. 142
    • Abrams, P.1    Lheritier, K.2    Steel, M.3
  • 36
    • 21244437845 scopus 로고    scopus 로고
    • Urinary continence during darifenacin therapy for overactive bladder (overactive bladder): Pooled data from phase III trials
    • Abst. 229
    • Abrams, P., Foote, J., Lheritier, K. Urinary continence during darifenacin therapy for overactive bladder (overactive bladder): pooled data from phase III trials [abstract]. Eur Urol Suppl 2005, 4: 60 (Abst. 229).
    • (2005) Eur Urol Suppl , vol.4 , pp. 60
    • Abrams, P.1    Foote, J.2    Lheritier, K.3
  • 37
    • 8444252588 scopus 로고    scopus 로고
    • Responder rates, a better way to express drug efficacy: Data from darifenacin pooled phase III studies
    • (August 25-27, Paris, France), Abst. 389
    • Abrams, P., Foote, J., Lheritier, K., Steel, M. Responder rates, a better way to express drug efficacy: data from darifenacin pooled phase III studies [abstract]. 34th Annual Meeting of the International Continence Society (August 25-27, Paris, France) 2004, Abst. 389 http://www. continet. org/publications/ 2004/pdf/0389.pdf.
    • (2004) 34th Annual Meeting of the International Continence Society
    • Abrams, P.1    Foote, J.2    Lheritier, K.3    Steel, M.4
  • 38
    • 0011884156 scopus 로고    scopus 로고
    • 3 antagonist for overactive bladder: Comparison with oxybutynin on ambulatory urodynamic monitoring and salivary flow
    • (September 18-21, Seoul, South Korea), Abst 221
    • 3 antagonist for overactive bladder: comparison with oxybutynin on ambulatory urodynamic monitoring and salivary flow [abstract]. 31st Annual Meeting of the International Continence Society (September 18-21, Seoul, South Korea) 2001, Abst 221. http://www.continet.org/publications/2001/ pdf/0221.pdf.
    • (2001) 31st Annual Meeting of the International Continence Society
    • Mundy, A.R.1    Abrams, P.2    Chapple, C.R.3    Neal, D.E.4
  • 39
    • 32044463731 scopus 로고    scopus 로고
    • 3 SRA), compared with oxybutynin in the treatment of patients with overactive bladder
    • in press
    • 3 SRA), compared with oxybutynin in the treatment of patients with overactive bladder. World J Urol 2005, in press.
    • (2005) World J Urol
    • Zinner, N.1    Tuttle, J.2    Marks, L.3
  • 40
    • 33747887310 scopus 로고    scopus 로고
    • 3 selective receptor antagonist, compared with oxybutynin in the treatment of patients with overactive bladder
    • (August 25-27, Paris, France), Abst. 378
    • 3 selective receptor antagonist, compared with oxybutynin in the treatment of patients with overactive bladder [abstract]. 34th Annual Meeting of the International Continence Society, (August 25-27, Paris, France) 2004, Abst. 378 http://www. continet.org/publications/2004/pdf/ 0378.pdf.
    • (2004) 34th Annual Meeting of the International Continence Society
    • Zinner, N.1    Tuttle, J.2    Marks, L.3
  • 41
    • 0030802061 scopus 로고    scopus 로고
    • Explicit criteria for determining potentially inappropriate medication use by the elderly
    • Beers, M.H. Explicit criteria for determining potentially inappropriate medication use by the elderly. Arch Intern Med 1997, 157: 1531-6.
    • (1997) Arch Intern Med , vol.157 , pp. 1531-1536
    • Beers, M.H.1
  • 42
    • 0345600187 scopus 로고    scopus 로고
    • Updating the Beers Criteria for potentially inappropriate medication use in older adults
    • Pick, D.M., Cooper, J.W., Wade, W.E., Waller, J.L., Maclean, J.R., Beers, M.H. Updating the Beers Criteria for potentially inappropriate medication use in older adults. Arch Intern Med 2003, 163: 2716-24.
    • (2003) Arch Intern Med , vol.163 , pp. 2716-2724
    • Pick, D.M.1    Cooper, J.W.2    Wade, W.E.3    Waller, J.L.4    Maclean, J.R.5    Beers, M.H.6
  • 44
    • 0030667817 scopus 로고    scopus 로고
    • A new questionnaire to assess the quality of life of urinary incontinent women
    • Kelleher, C.J., Cardozo, L.D., Khullar, V., Salvatore, S. A new questionnaire to assess the quality of life of urinary incontinent women. Br J Obstet Gynaecol 1997, 104: 1374-9.
    • (1997) Br J Obstet Gynaecol , vol.104 , pp. 1374-1379
    • Kelleher, C.J.1    Cardozo, L.D.2    Khullar, V.3    Salvatore, S.4
  • 45
    • 0038626769 scopus 로고    scopus 로고
    • Multinational study of reliability and validity of the King's Health Questionnaire in patients with overactive bladder
    • Reese, P.R., Pleil, A.M., Okano, G.J., Kelleher, C.J. Multinational study of reliability and validity of the King's Health Questionnaire in patients with overactive bladder. Qual Life Res 2003, 12: 427-42.
    • (2003) Qual Life Res , vol.12 , pp. 427-442
    • Reese, P.R.1    Pleil, A.M.2    Okano, G.J.3    Kelleher, C.J.4
  • 46
    • 26844548532 scopus 로고    scopus 로고
    • 3 selective receptor antagonist, in patients with overactive bladder
    • Abst. 1136
    • 3 selective receptor antagonist, in patients with overactive bladder [abstract]. BJU Int 2004, 94(Suppl 2): Abst. 1136.
    • (2004) BJU Int , vol.94 , Issue.SUPPL. 2
    • Chapple, C.1    Kelleher, C.2    Perrault, L.3
  • 47
    • 84878684643 scopus 로고    scopus 로고
    • Patient perceived quality of treatment is a valid method to assess the satisfaction, preference and willingness of patients to re-use treatment for overactive bladder
    • Abst. 69
    • Steel, M., Kahler, K. Patient perceived quality of treatment is a valid method to assess the satisfaction, preference and willingness of patients to re-use treatment for overactive bladder [abstract]. Prog Urol 2004, 14(Suppl 3): 23, Abst. 69.
    • (2004) Prog Urol , vol.14 , Issue.SUPPL. 3 , pp. 23
    • Steel, M.1    Kahler, K.2
  • 48
    • 84878686121 scopus 로고    scopus 로고
    • Patient satisfaction, preference, and willingness to reuse darifenacin in the treatment of overactive bladder
    • Abst. 1139
    • Glavind, K., Perrault, L. Patient satisfaction, preference, and willingness to reuse darifenacin in the treatment of overactive bladder [abstract]. BJU Int 2004, 94(Suppl 2): Abst. 1139.
    • (2004) BJU Int , vol.94 , Issue.SUPPL. 2
    • Glavind, K.1    Perrault, L.2
  • 49
    • 84878692157 scopus 로고    scopus 로고
    • Darifenacin versus oxybutynin for overactive bladder (OAB)
    • (October 13-17, Orlando, USA), Abst./Poster 4029
    • Abrams, P., Steel, M., Ebinger, U. Darifenacin versus oxybutynin for overactive bladder (OAB) [abstract]. WONCA/AAFP meeting (October 13-17, Orlando, USA) 2004, Abst./Poster 4029.
    • (2004) WONCA/AAFP Meeting
    • Abrams, P.1    Steel, M.2    Ebinger, U.3
  • 50
    • 33745196639 scopus 로고    scopus 로고
    • Central nervous system (CNS)-related adverse events in patients with overactive bladder (overactive bladder) treated with darifenacin versus tolterodine
    • Abst. 1134
    • Foote, J., Glavind, K., Kay, G. Central nervous system (CNS)-related adverse events in patients with overactive bladder (overactive bladder) treated with darifenacin versus tolterodine [abstract]. BJU Int 2004, 94(Suppl 2): Abst. 1134.
    • (2004) BJU Int , vol.94 , Issue.SUPPL. 2
    • Foote, J.1    Glavind, K.2    Kay, G.3
  • 51
    • 0036664806 scopus 로고    scopus 로고
    • 3 receptor selectivity
    • 3 receptor selectivity. Eur Urol Suppl 2002, 1 (Suppl): 23-8.
    • (2002) Eur Urol Suppl , vol.1 , Issue.SUPPL. , pp. 23-28
    • Andersson, K.-E.1
  • 53
    • 0038665188 scopus 로고    scopus 로고
    • Tolterodine and memory: Dry but forgetful
    • Womack, K.B., Heilman, K.M. Tolterodine and memory: dry but forgetful. Arch Neurol 2003, 60: 771-3.
    • (2003) Arch Neurol , vol.60 , pp. 771-773
    • Womack, K.B.1    Heilman, K.M.2
  • 54
    • 26844464517 scopus 로고    scopus 로고
    • Pharmacodynamic effects of darifenacin, a muscarinic receptor antagonist for the treatment of overactive bladder, in healthy volunteers
    • in press
    • Kay, G., Wesnes, K. Pharmacodynamic effects of darifenacin, a muscarinic receptor antagonist for the treatment of overactive bladder, in healthy volunteers. BJU Int 2005, in press.
    • (2005) BJU Int
    • Kay, G.1    Wesnes, K.2
  • 55
    • 12544253619 scopus 로고    scopus 로고
    • Assessment of cognitive function in the elderly population: Effects of darifenacin
    • Lipton, R.B., Kolodner, K., Wesnes, K. Assessment of cognitive function in the elderly population: effects of darifenacin. J Urol 2005, 173: 493-8.
    • (2005) J Urol , vol.173 , pp. 493-498
    • Lipton, R.B.1    Kolodner, K.2    Wesnes, K.3
  • 56
    • 0029935956 scopus 로고    scopus 로고
    • 1 muscarinic acetylcholine receptors in rat ventricular myocytes
    • 1 muscarinic acetylcholine receptors in rat ventricular myocytes. Circ Res 1996, 79: 86-93.
    • (1996) Circ Res , vol.79 , pp. 86-93
    • Sharma, V.K.1    Colecraft, H.M.2    Wang, D.X.3
  • 57
    • 23944509028 scopus 로고    scopus 로고
    • 3 selective receptor antagonist for the treatment of overactive bladder
    • 3 selective receptor antagonist for the treatment of overactive bladder. J Clin Pharm 2005, 45: 1038-47.
    • (2005) J Clin Pharm , vol.45 , pp. 1038-1047
    • Serra, D.B.1    Affrime, M.B.2    Bedigian, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.